Navigation Links
Childhood Urinary Tract Infection May Bring Lasting Harm to Kidneys
Date:8/5/2014

By
HealthDay Reporter

TUESDAY, Aug. 5, 2014 (HealthDay News) -- Urinary tract infections are the most common serious bacterial infections in young children, and almost one of every eight kids who gets one will end up with scarring on the kidneys and an increased risk of kidney failure later in life.

Identifying those kids early is critical, and researchers now report that a combination of three factors -- high fever, detection of kidney abnormalities via ultrasound and identification of the type of bacteria involved -- spots such patients as accurately as a very unpleasant catheter-based test does.

"We found that you more or less can predict the children who are at higher risk by looking at three different things when they come in," said study author Dr. Nader Shaikh, an assistant professor at the University of Pittsburgh and a pediatrician at the Children's Hospital of Pittsburgh.

In the past, doctors used a combination catheter/X-ray to detect children at greater risk for kidney scarring.

The test required using a catheter to fill a child's bladder with a special dye. Doctors then asked the child to urinate while being X-rayed, so they could see whether urine flow indicated a kidney problem.

Doctors used the X-ray test often in the 1960s and 1970s, but in recent years they have been moving away from it, said Dr. Kenneth Roberts, a pediatrician in Greensboro, N.C., who wrote an editorial accompanying the new study.

"It's very uncomfortable, very distressing and entails a good amount of radiation," Roberts said. "It is not only not worth putting all children through that procedure, but with this study we now have information that shows it's simply not justified."

To see whether there is a better option for finding kids at greater risk of kidney scarring, Shaikh and his colleagues reviewed existing data from previous studies involving 1,280 children aged 18 and younger.

About 15 percent of these children suffered kidney scarring from a urinary tract infection. The researchers found that three factors were strongly associated with scarring:

  • Fever of at least 102 degrees.
  • Infection with a bacteria other than E. coli.
  • Ultrasound readings that detected an abnormality in the kidney.

A model based on these factors predicted nearly 45 percent of children who ended up developing kidney scars, a rate only 3 percent to 5 percent less effective than models involving blood tests or the catheter/X-ray examination, the researchers reported.

The findings were published online Aug. 4 in the journal JAMA Pediatrics.

The test's real power comes in its ability to rule out children at risk, Shaikh noted.

"The prediction is not perfect," he said. "For more or less, we can say these 80 percent of kids aren't going to scar, we don't have to worry about them."

Doctors can step up observation of kids at greater risk for kidney scarring. "The main focus should be to prevent subsequent infections for those children," Shaikh said. "Every time you get a [urinary tract infection], you get a chance of scarring again."

Roberts agreed.

"Now that we know the groups at greatest risk, maybe we can come up with methods for decreasing inflammation during this infection and possibly preventing scars," he said. "We can back off the things we're doing that are distressing to children, and think about novel ways to preserve the kidneys of these children."

More information

Visit the U.S. National Institute of Diabetes and Digestive and Kidney Diseases for more on urinary tract infections in children.

SOURCES: Nader Shaikh, M.D., M.P.H., assistant professor, University of Pittsburgh, and pediatrician, Children's Hospital of Pittsburgh; Kenneth Roberts, M.D., pediatrician, Greensboro, N.C.; Aug. 4, 2014, JAMA Pediatrics, online


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New study identifies promising, achievable solutions to Nigerias childhood mortality crisis
2. Symptomatic behaviour in childhood strongly predicts psychiatric treatment as a young adult
3. Study identifies potential treatment for lethal childhood leukemia
4. Childhood Obesity May Raise Odds of Adult Liver Cancer
5. IADR/AADR publish studies on severe early childhood caries - proposes new classification
6. Could the Childhood Obesity Epidemic Be Ebbing?
7. Better health in adulthood starts with early prevention in childhood
8. Environment key to preventing childhood disabilities
9. Treating childhood obesity: A family affair
10. Pneumonia and preterm birth complications are the leading causes of childhood death
11. Experimental Drug Helps Fight Some Childhood Cancers, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Childhood Urinary Tract Infection May Bring Lasting Harm to Kidneys 
(Date:2/8/2016)... , ... February 08, 2016 , ... Guruji Mahendra Kumar ... 10th and 11th, 2016 in honor of his birthday on February 10th. During ... Mahendra Trivedi is known by over 250,000 people from over 40 different countries ...
(Date:2/7/2016)... Metamora, Michigan (PRWEB) , ... February 07, 2016 ... ... pelvic organ prolapse with the latest techniques and the most minimally invasive approaches. ... pelvic organ prolapse, particularly after menopause. Other risk factors include surgery to the ...
(Date:2/7/2016)... ... February 07, 2016 , ... ... has added Kybella® to his medical and surgical expertise. Technically known as deoxycholic ... injectable medication used as a non-surgical alternative for reduction of fat below the ...
(Date:2/6/2016)... ... ... With the FCPX LUT: Summer pack from Pixel Film Studios, ... is a Lookup Table that contains a mathematical formula for modifying an image. The ... manipulating each pixel, LUT's can change each color range differently, it gives the user ...
(Date:2/5/2016)... SARASOTA, Florida (PRWEB) , ... February 05, 2016 , ... ... an event he has completed every year since it started in 2003. This year, ... attracting the attention of fellow runners and NBA team the Miami Heat. , This ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... , Feb. 8, 2016 Velano Vascular, a ... for hospitalized patients and their practitioners, announced today that ... funding. Velano will use the proceeds from this financing, ... completed in January 2015, to support the development and ... and pediatric populations. Philadelphia ...
(Date:2/8/2016)... Calif. , Feb. 8, 2016  HemaFlo Therapeutics, Inc. ... (USPTO) has issued US Patent Number 9,119,880 covering the use ... Dale Peterson , PhD, HemaFlo,s founder, said, "We are ... --> Dale Peterson , PhD, HemaFlo,s founder, ... a powerful technology." --> Dale Peterson ...
(Date:2/8/2016)... NORTHBROOK, Ill. , Feb. 8, 2016  Astellas Pharma ... today announced the promotion of James Robinson as ... the company,s operations in North and South America ... president, Astellas Pharma US, representing the commercial organization in ... assumed in 2013. Masao Yoshida , who ...
Breaking Medicine Technology: