Navigation Links
Childbirth increases risk of ACPA-negative rheumatoid arthritis
Date:6/13/2013

Madrid, Spain, 13 June 2013: Epidemiological data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that pregnancy carried to childbirth (parity) increases the risk of ACPA-negative* rheumatoid arthritis (RA).

The increased risk was demonstrated in women aged 18-44 who have had a child (2.1, 95% CI 1.4-3.2), but not in older women, and was more pronounced among those women with delivery during the first year of symptoms.

RA is an autoimmune disease characterised by inflammation of the joints and tendons. As a chronic condition, RA can cause pain, stiffness, progressive joint destruction and deformity, and reduce physical function, quality of life and life expectancy. Prevalence varies between 0.3% and 1%, with the disease more common in women than men.

"It has been suggested that the risk of RA is decreased during pregnancy but increased after delivery. Our data demonstrates that the increased risk after delivery is only associated with ACPA-negative RA and not ACPA-positive RA."

"Our findings of different impact of parity history on the two subgroups of RA add further evidence to the notion that RA comprises two different disease entities with different aetiology," said lead author of the study Cecilia Orellana, Institute of Environmental Medicine, Karolinska Institutet, Karolinska University, Stockholm, Sweden.

The Swedish population-based EIRA (Epidemiological Investigation of RA) case-control study was comprised of 2,035 female cases aged 18-70, and 2,911 matched controls collected between 1996 and 2009. Parity, post-partum period before onset of symptoms and age at first birth were assessed by means of a questionnaire.

"Further studies are needed to fully explore the biological mechanisms behind our findings, but reproductive factors may partly explain the notoriously higher incidence of RA among women" Ms Orellana concluded.


'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-020-733-15364
European League Against Rheumatism
Source:Eurekalert

Page: 1

Related medicine news :

1. Fear of Childbirth Linked to Longer Labor, Study Says
2. Childbirth After 30 Lowers Risk of Endometrial Cancer: Study
3. Vanderbilt study looks at benefits of progestogens to prevent early childbirth
4. Delaying childbirth may reduce risk of an aggressive form of breast cancer
5. Love Hormone May Aid Womens Recovery After Childbirth
6. Depression risk among women in the military deployed after childbirth
7. Military Women Exposed to Combat After Childbirth Face Depression
8. Most New Mothers Skip Sex for at Least 6 Weeks After Childbirth
9. The no worries approach fails to identify Australian women with childbirth fear
10. Hospitals Enact Policies to Curb Early Childbirth
11. Childbirth Injury Attorneys with McDonaldWorley.com Offering Lawsuit Reviews for Nationwide Claims
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... ... ... “Cursed with a Curse: The Truth about Tithing”: a ... when breaking free from this misconception. “Cursed with a Curse: The Truth about ... Christian Faith Publishing, Lysa M. Harrison’s new book is a powerful and thought-provoking ...
(Date:9/22/2017)... ... ... “Fruit of the Spirit: “Love””: a delightful adventure of two friends who ... the Spirit: “Love”” is the creation of published author, Halimah Jones, who was born ... is an avid writer, her inspiration for “Fruit of the Spirit: “Love”” blossomed from ...
(Date:9/21/2017)... ... September 21, 2017 , ... With ProSlideshow Portrait from ... easy to do. Users can select from up to two layers of subject matter ... of a mouse all within Final Cut Pro X. , With ProSlideshow ...
(Date:9/21/2017)... (PRWEB) , ... September 21, 2017 , ... ... **An FDAnews Management Report**, http://www.fdanews.com/products/54818-promotional-communication      , In the competitive world of ... can get while staying in compliance with FDA rules. , The FDA has ...
(Date:9/21/2017)... ... September 21, 2017 , ... Innovatum ... at the Global GS1 Healthcare Conference 2017 in Chicago, IL on October 17-19, ... ensuring label quality and improving patient safety. , Microscan , a ...
Breaking Medicine News(10 mins):
(Date:9/9/2017)... -- Dealmed Medical Supplies, New York City,s ... drugs, vaccines, and specialty medical products and services, announced ... acquire Vantage Medical Supplies, a major distributor of medical ... York . ... practices, will operate under the Dealmed name as of ...
(Date:9/7/2017)... , Sept. 7, 2017  For nearly two decades, New Life Agency ... Assisted Reproduction Insurance industry. Today, New Life Agency announces a powerful three-way ... ... ... http://pharmacarecard.com/ (PRNewsfoto/PharmaCareCard) ...
(Date:9/7/2017)... 7, 2017  Zimmer Biomet Holdings, Inc. (NYSE and ... announced that it will be participating in the Morgan ... the Grand Hyatt hotel in New York.  Zimmer Biomet ... a.m. Eastern Time. A live webcast of ... Relations website at http://investor.zimmerbiomet.com .   ...
Breaking Medicine Technology: