Navigation Links
Childbirth increases risk of ACPA-negative rheumatoid arthritis
Date:6/13/2013

Madrid, Spain, 13 June 2013: Epidemiological data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that pregnancy carried to childbirth (parity) increases the risk of ACPA-negative* rheumatoid arthritis (RA).

The increased risk was demonstrated in women aged 18-44 who have had a child (2.1, 95% CI 1.4-3.2), but not in older women, and was more pronounced among those women with delivery during the first year of symptoms.

RA is an autoimmune disease characterised by inflammation of the joints and tendons. As a chronic condition, RA can cause pain, stiffness, progressive joint destruction and deformity, and reduce physical function, quality of life and life expectancy. Prevalence varies between 0.3% and 1%, with the disease more common in women than men.

"It has been suggested that the risk of RA is decreased during pregnancy but increased after delivery. Our data demonstrates that the increased risk after delivery is only associated with ACPA-negative RA and not ACPA-positive RA."

"Our findings of different impact of parity history on the two subgroups of RA add further evidence to the notion that RA comprises two different disease entities with different aetiology," said lead author of the study Cecilia Orellana, Institute of Environmental Medicine, Karolinska Institutet, Karolinska University, Stockholm, Sweden.

The Swedish population-based EIRA (Epidemiological Investigation of RA) case-control study was comprised of 2,035 female cases aged 18-70, and 2,911 matched controls collected between 1996 and 2009. Parity, post-partum period before onset of symptoms and age at first birth were assessed by means of a questionnaire.

"Further studies are needed to fully explore the biological mechanisms behind our findings, but reproductive factors may partly explain the notoriously higher incidence of RA among women" Ms Orellana concluded.


'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-020-733-15364
European League Against Rheumatism
Source:Eurekalert

Page: 1

Related medicine news :

1. Fear of Childbirth Linked to Longer Labor, Study Says
2. Childbirth After 30 Lowers Risk of Endometrial Cancer: Study
3. Vanderbilt study looks at benefits of progestogens to prevent early childbirth
4. Delaying childbirth may reduce risk of an aggressive form of breast cancer
5. Love Hormone May Aid Womens Recovery After Childbirth
6. Depression risk among women in the military deployed after childbirth
7. Military Women Exposed to Combat After Childbirth Face Depression
8. Most New Mothers Skip Sex for at Least 6 Weeks After Childbirth
9. The no worries approach fails to identify Australian women with childbirth fear
10. Hospitals Enact Policies to Curb Early Childbirth
11. Childbirth Injury Attorneys with McDonaldWorley.com Offering Lawsuit Reviews for Nationwide Claims
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... ... Angel”: a heartwarming and earnest tale of faith and believing in the path ... the creation of published author, Marjorie Lund-Fontaine, a former professional violinist, alumnus of The ... of her new book, Marjorie says, “‘The Angel’ was written as a fairytale, but ...
(Date:1/20/2017)... ... January 20, 2017 , ... D R ... Pressure (OPEP) device, was featured in a study indicating superior performance against competitive ... “Analysis of Three Oscillating Positive Expiratory Pressure Devices During Simulated Breathing“ was ...
(Date:1/20/2017)... , ... January 20, 2017 , ... “Knowledge is God’s ... guided by faith. “Knowledge is God’s Lighthouse” is the creation of published author, Gene ... novels, and poetry collections. , “I have been writing since high school and ...
(Date:1/19/2017)... ... January 20, 2017 , ... Today, the Centers for ... in four of CMS’s Alternative Payment Models (APMs) in 2017. Clinicians who participate in ... APMs are an important part of the Administration’s effort to build a system that ...
(Date:1/19/2017)... ... January 19, 2017 , ... Wells Pharmacy ... enhancement of their 503A compounding pharmacy located in Ocala, Florida. , Meeting ... and patients throughout the United States for high-quality human anti-aging and wellness ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , Jan. 19, 2017   Science Exchange ... excited to announce that the first five replication ...  (RP:CB) have been published in eLife today. Despite ... represents the first practical evaluation of reproducibility rates ... reproducible studies. Unlike other assessments of reproducibility, the ...
(Date:1/19/2017)... January 18, 2017 , , Marks E-QURE ... distribution agreement, following similar agreements in Israel ... Wound care is $2 5 billion ... E-QURE Corp. (OTCQB: EQUR), a leader in medical devices for the treatment of ... Médica Equipos Médicos S.A.S. (TeckMedica) in Colombia for the ...
(Date:1/19/2017)... The drug delivery technology market is projected ... 1,179.20 billion in 2016, at a CAGR of 7.2% ... diseases, increasing demand for biologics, technological advancements, and new ... this market. Whereas, self-administration & home care and rising ... opportunities for players operating in this market. On the ...
Breaking Medicine Technology: