Navigation Links
Childbirth increases risk of ACPA-negative rheumatoid arthritis
Date:6/13/2013

Madrid, Spain, 13 June 2013: Epidemiological data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that pregnancy carried to childbirth (parity) increases the risk of ACPA-negative* rheumatoid arthritis (RA).

The increased risk was demonstrated in women aged 18-44 who have had a child (2.1, 95% CI 1.4-3.2), but not in older women, and was more pronounced among those women with delivery during the first year of symptoms.

RA is an autoimmune disease characterised by inflammation of the joints and tendons. As a chronic condition, RA can cause pain, stiffness, progressive joint destruction and deformity, and reduce physical function, quality of life and life expectancy. Prevalence varies between 0.3% and 1%, with the disease more common in women than men.

"It has been suggested that the risk of RA is decreased during pregnancy but increased after delivery. Our data demonstrates that the increased risk after delivery is only associated with ACPA-negative RA and not ACPA-positive RA."

"Our findings of different impact of parity history on the two subgroups of RA add further evidence to the notion that RA comprises two different disease entities with different aetiology," said lead author of the study Cecilia Orellana, Institute of Environmental Medicine, Karolinska Institutet, Karolinska University, Stockholm, Sweden.

The Swedish population-based EIRA (Epidemiological Investigation of RA) case-control study was comprised of 2,035 female cases aged 18-70, and 2,911 matched controls collected between 1996 and 2009. Parity, post-partum period before onset of symptoms and age at first birth were assessed by means of a questionnaire.

"Further studies are needed to fully explore the biological mechanisms behind our findings, but reproductive factors may partly explain the notoriously higher incidence of RA among women" Ms Orellana concluded.


'/>"/>

Contact: EULAR Press Office
eularpressoffice@cohnwolfe.com
44-020-733-15364
European League Against Rheumatism
Source:Eurekalert

Page: 1

Related medicine news :

1. Fear of Childbirth Linked to Longer Labor, Study Says
2. Childbirth After 30 Lowers Risk of Endometrial Cancer: Study
3. Vanderbilt study looks at benefits of progestogens to prevent early childbirth
4. Delaying childbirth may reduce risk of an aggressive form of breast cancer
5. Love Hormone May Aid Womens Recovery After Childbirth
6. Depression risk among women in the military deployed after childbirth
7. Military Women Exposed to Combat After Childbirth Face Depression
8. Most New Mothers Skip Sex for at Least 6 Weeks After Childbirth
9. The no worries approach fails to identify Australian women with childbirth fear
10. Hospitals Enact Policies to Curb Early Childbirth
11. Childbirth Injury Attorneys with McDonaldWorley.com Offering Lawsuit Reviews for Nationwide Claims
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... “Vintage and Harvest A Cultivation of Christian ... Bible teacher residing in North Carolina with his wife, Anna Marie. He and his ... six grandchildren. David is also the author of “Shadow and Substance.” , “Love, the ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... In 2016 ... now estimates that there could be four million Zika-related cases in the Americas within ... with numbers of US cases reported per year skyrocketing to an estimated 329,000. Yet, ...
(Date:3/23/2017)... Virginia (PRWEB) , ... March 23, 2017 , ... ... public health services to their communities, 16 more public health departments have been ... week’s decisions bring another 4.5 million people into the expanding network of communities ...
(Date:3/23/2017)... ... ... The IoT (Internet of Things) is revolutionizing the way the world operates. ... individual consumers alike. Laboratories can maximize their profit margin by increasing throughput. ... to $11 trillion dollars by the year 2025. McKinsey expects the IoT to have ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... and businesses of the Norwalk and Vermillion areas, celebrates the newest charity ... is a nonprofit, community-based substance abuse prevention and peer recovery support organization ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... -- The Board of Directors of Nordic Nanovector ... including the complete 2016 Annual Accounts with notes. The report ... website in the section Investor Relations/Reports and presentations/Annual Reports. ... For further ... Financial Officer Cell: +47-91-51-95-76 Email: ir@nordicnanovector.com ...
(Date:3/23/2017)... Research and Markets has announced the addition ... Replacement Procedure By Technique, Repair Procedure By Technique, By Region, By ... ... forecasted to grow at a CAGR of 13.35% during 2016-2021 ... rising aging population, growth in population with heart disease and rising ...
(Date:3/23/2017)... 2017 As a result of diagnostic ... prevalence of allergic diseases, cutting edge developments in ... the ways in which pharmaceutical and biotech companies ... to be both a high quality meeting and ... groups, immunologists, research scholars and doctors. The event ...
Breaking Medicine Technology: