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Child-specific doses for pediatric PET patients
Date:2/1/2010

imaging for the best diagnosis possible.

Image quality for PET depends strongly on the patient's weight and body build. In other words, the larger and heavier the patient, the more injection dose or possibly a longer scan time is needed to obtain a quality image. For patients who are lighter and have less body masssuch as in pediatric patientsless injection dose or a reduced scan time may still allow for high-quality images.

"The results of this study show that, due to children's relatively small size and light weight, it is possible to reduce radiological dose (or scan time) while preserving image quality as compared to PET imaging in adults," said Dr. Accorsi, whose research was supported through a Research Fellow Award by the Society for Pediatric Radiology Research and Education Foundation. "Minimizing exposure to radiation is important to all patients, but especially for young children."

CHOP-Penn researchers acquired and analyzed data from 73 patients. The patients' weight ranged from 25 pounds to 200 pounds. Researchers report in their study that when following an injection protocol proportional to weight, the data quality of PET images was found to improve with decreasing weight. The study provides practical injection protocols to trade this advantage for decreased scan time or dose at constant image quality.

Studies such as the one published in JNM are helping physicists and physicians gather new data about improving dose regimens to get the highest-quality diagnostic image while using the lowest amount of radiation practical, adhering to the "As Low As Reasonably Achievable" (ALARA) principle.


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Contact: Amy Shaw
ashaw@snm.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

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