Navigation Links
Child-specific doses for pediatric PET patients
Date:2/1/2010

Reston, Va. Studies have shown positron emission tomography's (PET) value as a minimally invasive, painless and safe diagnostic tool for many pediatric conditions. In a study published in the February issue of The Journal of Nuclear Medicine (JNM), researchers at the Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn) gathered data that may provide clinicians with new formulasspecific to pediatricsto calculate the amount of radiotracer that should be injected based on the patient's weight.

"These findings mean that PETa very common nuclear medicine procedurecan be used in children with methods that are even more patient-specific than those currently employed," said Roberto Accorsi, Ph.D., former research assistant professor of radiology at CHOP-Penn and lead author of the study.

This study is one more contribution to the medical imaging community's overall efforts to reduce radiation dose to children. Nuclear medicine specialists are continuously refining methodologies in order to preserve image quality and minimize radiation exposure during pediatric PET exams. Since medical research published in recent years highlights the health risks of exposure to ionizing radiation, many have looked to the medical community for ways to curb exposure during medical imaging exams. Although the nuclear medicine exam's benefits to the patient far outweigh any potential risks associated with radiation, the nuclear medicine community seeks to uphold practices that are consistent and mindful of patients' concerns.

In nuclear medicine, there are well-established guidelines for administering radiopharmaceutical doses for adults; however, there is little guidance for administering pediatric doses. Thus, the CHOP-Penn study sets out to examine how nuclear medicine physicians can take into consideration a child's lighter weight and body size and adjust the dose and scan time accordingly, while maintaining high-quality imaging for the best diagnosis possible.

Image quality for PET depends strongly on the patient's weight and body build. In other words, the larger and heavier the patient, the more injection dose or possibly a longer scan time is needed to obtain a quality image. For patients who are lighter and have less body masssuch as in pediatric patientsless injection dose or a reduced scan time may still allow for high-quality images.

"The results of this study show that, due to children's relatively small size and light weight, it is possible to reduce radiological dose (or scan time) while preserving image quality as compared to PET imaging in adults," said Dr. Accorsi, whose research was supported through a Research Fellow Award by the Society for Pediatric Radiology Research and Education Foundation. "Minimizing exposure to radiation is important to all patients, but especially for young children."

CHOP-Penn researchers acquired and analyzed data from 73 patients. The patients' weight ranged from 25 pounds to 200 pounds. Researchers report in their study that when following an injection protocol proportional to weight, the data quality of PET images was found to improve with decreasing weight. The study provides practical injection protocols to trade this advantage for decreased scan time or dose at constant image quality.

Studies such as the one published in JNM are helping physicists and physicians gather new data about improving dose regimens to get the highest-quality diagnostic image while using the lowest amount of radiation practical, adhering to the "As Low As Reasonably Achievable" (ALARA) principle.


'/>"/>

Contact: Amy Shaw
ashaw@snm.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

Related medicine news :

1. Overdoses From Prescription Painkillers on the Rise
2. More Than 4 Million Doses of H1N1 Vaccine Allocated to Pennsylvania Since Start of Vaccination Effort
3. Nearly 5 Million Doses of Nasal Swine Flu Vaccine Recalled
4. Variable Doses of Radiation Raise Safety Concerns for CT Procedures
5. Nearly 3 Million Doses of H1N1 Vaccine Allocated to Pennsylvania since Start of Vaccination Effort
6. Heart Failure Drug May Help More in Higher Doses
7. Medical Tests Hit Heart Patients With High Doses of Radiation
8. FDA Initiative Seeks to Reduce Accidental Overdoses
9. 1 Million More Doses of Swine Flu Vaccine on Hand
10. New research suggests how low doses of radiation can cause heart disease and stroke
11. Health Department Announces First Doses of H1N1 Vaccine Arrive in Pennsylvania
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... Braunfels, TX (PRWEB) , ... March 23, 2017 , ... ... new clinic, located at 960 Gruene Road in Building 2. The clinic is the ... Dr. Andrew Bennett, PT, says opening the company’s second New Braunfels location brings things ...
(Date:3/23/2017)... ... ... The IoT (Internet of Things) is revolutionizing the way the world operates. ... and individual consumers alike. Laboratories can maximize their profit margin by increasing throughput. ... trillion to $11 trillion dollars by the year 2025. McKinsey expects the IoT to ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... 82% of adults are unaware of the ... do not brush their teeth the minimum two times a day that dentists recommend. The ... missing 51 million hours of school and adults missing 164 million hours of work each ...
(Date:3/23/2017)... ... ... March is National Kidney Month – the perfect time to pause and ... health. Every day, two kidneys filter about 120 to 150 quarts of blood. Put ... waste, regulating fluid levels and blood pressure, supporting bone health and promoting red blood ...
(Date:3/23/2017)... ... March 23, 2017 , ... The StayWell Company announced today ... accreditation covers StayWell’s asthma, coronary artery disease, congestive heart failure, chronic obstructive pulmonary ... have excellent programs for the delivery and improvement of disease management and that ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... DUBLIN , Mar 23, 2017 Research ... Electrophoresis Market 2017-2021" report to their offering. ... The global capillary electrophoresis market ... The report, Global Capillary Electrophoresis Market 2017-2021, has ... industry experts. The report covers the market landscape and its growth ...
(Date:3/23/2017)... -- CENTRO DE IMAGEM DIAGNOSTICOS S.A. (" Company "), ... 6,404/76 and Instruction 358/02 of the Brazilian Securities and ... market in general that it entered yesterday, as a ... Imagem Ltda. (" CDI "), into an agreement for ... (" Partnership " and " Acquisition "). ...
(Date:3/23/2017)... -- Ascendis Pharma A/S (Nasdaq: ASND), a biopharmaceutical company ... unmet medical needs in rare diseases, today announced that ... on Monday, April 3 during ENDO 2017, the annual ... Florida , to discuss new data regarding its ... PTH and TransCon CNP). Ascendis is presenting ...
Breaking Medicine Technology: