Navigation Links
Child-specific doses for pediatric PET patients
Date:2/1/2010

Reston, Va. Studies have shown positron emission tomography's (PET) value as a minimally invasive, painless and safe diagnostic tool for many pediatric conditions. In a study published in the February issue of The Journal of Nuclear Medicine (JNM), researchers at the Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn) gathered data that may provide clinicians with new formulasspecific to pediatricsto calculate the amount of radiotracer that should be injected based on the patient's weight.

"These findings mean that PETa very common nuclear medicine procedurecan be used in children with methods that are even more patient-specific than those currently employed," said Roberto Accorsi, Ph.D., former research assistant professor of radiology at CHOP-Penn and lead author of the study.

This study is one more contribution to the medical imaging community's overall efforts to reduce radiation dose to children. Nuclear medicine specialists are continuously refining methodologies in order to preserve image quality and minimize radiation exposure during pediatric PET exams. Since medical research published in recent years highlights the health risks of exposure to ionizing radiation, many have looked to the medical community for ways to curb exposure during medical imaging exams. Although the nuclear medicine exam's benefits to the patient far outweigh any potential risks associated with radiation, the nuclear medicine community seeks to uphold practices that are consistent and mindful of patients' concerns.

In nuclear medicine, there are well-established guidelines for administering radiopharmaceutical doses for adults; however, there is little guidance for administering pediatric doses. Thus, the CHOP-Penn study sets out to examine how nuclear medicine physicians can take into consideration a child's lighter weight and body size and adjust the dose and scan time accordingly, while maintaining high-quality imaging for the best diagnosis possible.

Image quality for PET depends strongly on the patient's weight and body build. In other words, the larger and heavier the patient, the more injection dose or possibly a longer scan time is needed to obtain a quality image. For patients who are lighter and have less body masssuch as in pediatric patientsless injection dose or a reduced scan time may still allow for high-quality images.

"The results of this study show that, due to children's relatively small size and light weight, it is possible to reduce radiological dose (or scan time) while preserving image quality as compared to PET imaging in adults," said Dr. Accorsi, whose research was supported through a Research Fellow Award by the Society for Pediatric Radiology Research and Education Foundation. "Minimizing exposure to radiation is important to all patients, but especially for young children."

CHOP-Penn researchers acquired and analyzed data from 73 patients. The patients' weight ranged from 25 pounds to 200 pounds. Researchers report in their study that when following an injection protocol proportional to weight, the data quality of PET images was found to improve with decreasing weight. The study provides practical injection protocols to trade this advantage for decreased scan time or dose at constant image quality.

Studies such as the one published in JNM are helping physicists and physicians gather new data about improving dose regimens to get the highest-quality diagnostic image while using the lowest amount of radiation practical, adhering to the "As Low As Reasonably Achievable" (ALARA) principle.


'/>"/>

Contact: Amy Shaw
ashaw@snm.org
703-652-6773
Society of Nuclear Medicine
Source:Eurekalert

Related medicine news :

1. Overdoses From Prescription Painkillers on the Rise
2. More Than 4 Million Doses of H1N1 Vaccine Allocated to Pennsylvania Since Start of Vaccination Effort
3. Nearly 5 Million Doses of Nasal Swine Flu Vaccine Recalled
4. Variable Doses of Radiation Raise Safety Concerns for CT Procedures
5. Nearly 3 Million Doses of H1N1 Vaccine Allocated to Pennsylvania since Start of Vaccination Effort
6. Heart Failure Drug May Help More in Higher Doses
7. Medical Tests Hit Heart Patients With High Doses of Radiation
8. FDA Initiative Seeks to Reduce Accidental Overdoses
9. 1 Million More Doses of Swine Flu Vaccine on Hand
10. New research suggests how low doses of radiation can cause heart disease and stroke
11. Health Department Announces First Doses of H1N1 Vaccine Arrive in Pennsylvania
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes ... a mock evacuation of the facility as part of a disaster drill on October ... Hose EMS and Shelton City Emergency Manager, as well as the Connecticut Long ...
(Date:10/13/2017)... ... 2017 , ... Ellevate Network, the leading network for professional women, brought together ... equality at their inaugural Summit in New York City in June. The event was ... of over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... will be giving viewers the lowdown on sciatica in a new episode of ... that focuses on current events and innovation and investigates each subject in-depth with ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the loss ... author, William Nowers. Captain Nowers and his wife, Millie, have six children, ten ... the Navy. Following his career as a naval aviator and carrier pilot, he ...
(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... 2017  According to the Centers for Disease Control and Prevention (CDC), ... PhysicianOne Urgent Care is helping communities across Massachusetts , ... by offering no-cost* flu shots through the end of the month. ... insurance regulations. ... get a flu shot is by the end of October, according to ...
(Date:10/2/2017)... Oct. 2, 2017  Eli Lilly and Company (NYSE: ... for the third quarter of 2017 on Tuesday, October ... on that day with the investment community and media ... The conference call will begin at 9 a.m. Eastern ... a live webcast of the conference call through a ...
(Date:10/2/2017)... , Oct. 2, 2017 The Rebound mobile ... the struggle to reverse the tide of prescription drug addiction. ... regulating their medicine intake and stepping down their dosage in ... to launch in December 2017; the first 100,000 people to ... more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology: