Navigation Links
Chest radiation cancer patients with risk factors should have CV screening every 5-10 years
Date:7/16/2013

Sophia Antipolis, 16 July 2013: Cancer patients who receive chest radiation should be screened for heart disease every 5-10 years, according to the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology (ESC) and the American Society of Echocardiography (ASE).

Their recommendations are outlined in the first expert consensus statement on screening for radiation-induced heart disease (RIHD), published today in European Heart Journal Cardiovascular Imaging.1

Professor Patrizio Lancellotti, chair of the expert task force and president of the EACVI, said: "The prevalence of radiation-induced heart disease is increasing because the rate of cancer survival has improved. It's a long term risk, and RIHD manifests 5-20 years after the radiation dose."

He added: "Survivors of Hodgkin's lymphoma and breast cancer received high doses of radiation on their chest under the old treatment regimes. Over time these patients can develop RIHD in the heart valves, myocardium, vessels including the aorta, the pericardium, and the coronary arteries. Their risk of death from coronary artery disease, myocardial ischemia and myocardial infarction is increased."

Professor Lancellotti continued: "Radiotherapy is now given in lower doses but patients are still at increased risk of RIHD, particularly when the heart is in the radiation field. This applies to patients treated for lymphoma, breast cancer and oesophageal cancer. Patients who receive radiotherapy for neck cancer are also at risk because lesions can develop on the carotid artery and increase the risk of stroke."

RIHD is estimated to occur in 10-30% of patients who receive chest radiotherapy within 5-10 years post-treatment. Cardiac structural and functional changes after radiation can be detected early using echocardiography, cardiac computed tomography (CT), cardiac magnetic resonance (CMR) and nuclear cardiology. But screening for RIHD is not routine practice.

In the report the expert group recommends:

  • Before initiating any chest radiotherapy, patients should have screening for RIHD risk factors, a clinical examination, and a baseline echocardiographic evaluation
  • Patients who receive chest radiation for cancers including breast cancer or lymphoma should receive cardiac screening 5 years post-treatment if they have any cardiac abnormality or are at high risk and 10 years post-treatment if not
  • Cardiovascular screening should be repeated every 5-10 years depending on the presence of cardiac abnormalities and the level of risk
  • All patients who had chest radiation for cancer in the past should receive a cardiac examination starting with echocardiography.

Patients are at high risk of RIHD if they have radiation for left-sided breast cancer, have a high dose of radiation (often used in young people), the irradiated area is not shielded, have a high dose of anthracyclines (chemotherapy), or have cardiovascular risk factors including smoking, obesity and inactivity.

Professor Lancellotti said: "We wrote the expert consensus to raise the alarm that the risks of radiation-induced heart disease should not be ignored," said Professor Lancellotti. Cardiovascular screening is needed before and after radiation therapy to detect RIHD early, follow up patients at appropriate intervals, and define the optimal timing for any kind of intervention."

He added: "Echocardiography is the first line of imaging assessment but in some patients we need other examinations including stress imaging, CT and CMR. For instance we can precisely assess the presence of myocardial fibrosis using CMR and more accurately assess cardiac calcification using CT."

Professor Lancellotti concluded: "A registry of RIHD is needed in Europe to determine the true prevalence of the disease and collect outcome data," he said.. "This together with screening should reduce the risk of patients developing RIHD and enable us to treat it early when it does occur."


'/>"/>

Contact: Jacqueline Partarrieu
press@escardio.org
33-492-947-756
European Society of Cardiology
Source:Eurekalert

Related medicine news :

1. Decision support system translates into high percentage of positive chest CT examinations
2. High-Tech CT Scan May Get People With Chest Pain Home Faster
3. Women, Young Adults Misinterpret Chest Pain: Study
4. 5 Steps Would Lower Preemie Rates in Richest Countries: Study
5. UGA study finds anxiety linked to chest pain in children
6. First patients in US receive non-surgical device of sunken chest syndrome
7. Study: Chest CT Scans May Increase Breast Cancer Risk
8. Crittenton Hospital Medical Center in Rochester, MI Welcomes Two Certified Nurse Midwives (CNMs) from Women's Excellence in Midwifery
9. The greatest medical resource youve never heard of: Rochester epidemiology project
10. LaserTouch Aesthetics Is Excited To Announce The Addition Of Electrolysis to the Array of Services Offered at its White Plains, Westchester location
11. Augmentative Communication Talking Keyboard Designed by Chester Creek Technologies Now Offered by Rehabmart.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... ... 24, 2016 , ... EB Medicine presented its first-ever “Issue ... conference in Ponte Vedra Beach, FL. The awards honor the outstanding work of ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the ...
(Date:6/24/2016)... ... , ... National recruitment firm Slone Partners is pleased to announce ... experience, as Vice President of North American Capital Sales at HTG Molecular . ... sales team in the commercialization of the HTG EdgeSeq system and associated reagents in ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 ... the addition of the " Global Markets for ... This report focuses on ... updated review, including its applications in various applications. The ... which includes three main industries: pharmaceutical and biotechnology, food ...
(Date:6/24/2016)... 2016 Research and Markets has announced ... Diagnostic Tests" report to their offering. ... The World Market for Companion Diagnostics covers ... Market analysis in the report includes the following: ... Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
Breaking Medicine Technology: