Navigation Links
Chemotherapy plus targeted therapies shows improved survival in advance-stage lung cancer patients
Date:11/13/2008

The combination of traditional chemotherapy agents with targeted therapies called monoclonal antibodies showed no safety concerns and improved survival in patients with advanced non-small cell lung cancer according to a study presented at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology, sponsored by ASTRO, ASCO, IASLC and the University of Chicago.

The combination of bevacizumab and chemotherapy has been shown to increase the survival of patients with incurable non-small cell lung cancer. cetuximab has recently demonstrated improved survival when given in combination with platinum based chemotherapy. Based on this information, researchers from M.D. Anderson Cancer Center in Houston, Fred Hutchison Cancer Research Center and the Cancer Research and Biostatistical Clinical Trials Consortium (CRAB), both in Seattle, the Cancer Center of Kansas in Wichita, Kan., Central Illinois CCOP in Springfield, Ill., the University of Kansas in Kansas City, Kan., and U.C. Davis Cancer Center in Sacramento, all part of the South West Oncology Group, sought to investigate the safety and efficacy of the combination of the four drugs in this multi-center phase II clinical trial.

This study, the first reported study of these two targeted therapies (bevacizumab and cetuximab) with chemotherapy (carboplatin and paclitaxel), combined the four drugs as first-line therapy in advanced lung cancer patients. The goal of this study was to assess the safety of the four drug regimen. No safety concerns were seen when compared with other treatments. Additionally, in the 104 patients evaluated between August 2006 and September 2007, improved survival was observed.

"The combination of multiple targeted therapies in addition to chemotherapy may be the future of treatment in lung cancer," said Edward Kim, M.D., lead author of the study and an assistant professor in the department of thoracic/head and neck medical oncology at M.D. Anderson Cancer Center. "Blocking mor
'/>"/>

Contact: Beth Bukata
bethb@astro.org
703-839-7332
American Society for Therapeutic Radiology and Oncology
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Chemotherapy may be culprit for fatigue in breast cancer survivors
2. Replidyne Pipeline Featured at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy
3. To evade chemotherapy, some cancer cells mimic stem cells
4. New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas
5. PET scans can accurately detect a breast tumors response to chemotherapy
6. Chemotherapy with gemcitabine delays progression of operable pancreatic cancer
7. Medicare modernization act did not change chemotherapy as feared
8. HER-2 status predicts success of chemotherapy in breast cancer treatment, study finds
9. Cancer conflict with chemotherapy treatment
10. Intra-arterial combination chemotherapy induces long-term survival for hepatocellular carcinoma
11. Jefferson researchers show chemotherapy and radiation together extend lung cancer patients lives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2009)Wind Turbines are popping up in the most unusual places, and to do everything from growing mushrooms, making wine to keeping prisoners in jail! , (PRWEB) December 5, 2009 -- W
(Date:12/4/2009)SAN FRANCISCO, Dec. 4 Medithrive, Inc. has won the Patient,s Choice Award as the favorite dispensary in the SF Bay Area by popular vote conducted by the online website, www.weedmaps.com. Despite on
(Date:12/4/2009)KANSAS CITY, Mo., Dec. 4 The large, two-day free health clinic sponsored by the National Association of Free Clinics (NAFC) in Kansas City on Wednesday and Thursday is not just for the sick but also
(Date:12/4/2009)WASHINGTON, Dec. 4 In response to the U.S. Justice Department Drug Enforcement Agency,s (DEA) classification of boldione, desoxymethyltestosterone, and 19-nor-4,9(10)-androstadienedione as "anabolic
(Date:12/4/2009)Case Western Reserve University researchers, from the School of Medicine,s Department of Nutrition, discovered two new metabolic pathways by which products of lipid peroxidation and some drugs of abus
Breaking Medicine News(10 mins):Health News:Distributor Announces New Applications for Wind Turbines 2Health News:Distributor Announces New Applications for Wind Turbines 3Health News:Free Health Clinic Event Is Not Just for the Sick 2Health News:Natural Products Association Issues Statement on DEA's Steroid Classification Action 2Health News:Case Western Reserve researchers' new pathway discovery published as 'Paper of the Week' 2
...saster Giving Program Provide,Financial Support, ...ripped through the South Tuesday night resulting i...entucky, Tennessee, Alabama and,Mississippi. The t...and search and rescue workers, and lending,emotion...
...)Perhaps the only positive spin one can put on the...uncommon. Other than that, the news is bad. It is ...the prime of their lives, and the limited treatmen... of cancer. , One approach focuses on a gene cal...
...dation of,America (LFA) is proud to unveil new pub...Five new booklets and eleven fact sheets provide t...diagnosis and treatment., The publications featur.... Developed in consultation with the nation,s,lead...
...application of high throughput DNA sequencing tec...eak, scientists from Columbia University Mailman S...iseases Reference Laboratory (VIRDL) in Melbourne,...who received organs from a single donor in Victori...
...and Net Income in Company History, BELLEVUE, Wash... leading online provider of health, beauty, vision...cial results for the fourth,quarter and fiscal yea...eved record gross margins in the fourth quarter,of...
...n Home Resident regain mobility and,Be Active, NE...a "sweetheart with a sweet tooth" say his friends ...ison wore out a borrowed power wheelchair,from del...COOTER Store has donated a new power wheelchair to...
Other Medicine News:Health News:American Red Cross Responds to Tornadoes in the Southeast 2Health News:Gene plays 'Jekyll and Hyde' in brain cancer 2Health News:Gene plays 'Jekyll and Hyde' in brain cancer 3Health News:Lupus Foundation of America Releases New Patient Education Series 2Health News:Scientists confirm new virus responsible for deaths of transplant recipients in Australia 2Health News:Scientists confirm new virus responsible for deaths of transplant recipients in Australia 3Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 2Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 3Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 4Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 5Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 6Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 7Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 8Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 9Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 10Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 11Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 12Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 13Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 14Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 15Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 16Health News:drugstore.com inc. Achieves GAAP Profitability in the Fourth Quarter of 2007 17Health News:The SCOOTER Store Donates Power Wheelchair to New Braunfels Car Crash Victim 2
(Date:12/3/2009)DOYLESTOWN, Pa., Dec. 3 Ted Karkus, Chairman and CEO of The Quigley Corporation, (Nasdaq: QGLY ) www.quigleyco.com announced today that the Company has completed its evaluation of its opportunitie
(Date:12/3/2009)WILMINGTON, Del., Dec. 3 ParagonRx, a Delaware-based company specializing in pharmaceutical risk management and optimal medication use, will host a free webinar on Wednesday, Dec. 9, on the FDA,s dra
(Date:12/3/2009)DURHAM, N.C., Dec. 3 In response to the increasingly critical role of healthcare information technologies in the evolving healthcare delivery system, Duke Medicine has created the Duke Center for Hea
Breaking Medicine Technology:Quigley CEO, Ted Karkus, Announces Phase One of 2010 Strategic Plan; Karkus Reports that the Primary Focus will be on Leveraging its OTC Platform; Company Aggressively Seeking Product Acquisitions and Line Extensions which Leverage its Distribution 2Quigley CEO, Ted Karkus, Announces Phase One of 2010 Strategic Plan; Karkus Reports that the Primary Focus will be on Leveraging its OTC Platform; Company Aggressively Seeking Product Acquisitions and Line Extensions which Leverage its Distribution 3Duke Medicine to Train Healthcare Professionals in Health Informatics 2Duke Medicine to Train Healthcare Professionals in Health Informatics 3Study shows promise for new cancer stopping therapy 48649 1Study shows promise for new cancer stopping therapy 48649 2Brown 26 Toland Announces 2008 Financial Results 48645 1Brown 26 Toland Announces 2008 Financial Results 48645 2Carrier Increases Energy Efficiency at Hartford Hospital 48640 1Carrier Increases Energy Efficiency at Hartford Hospital 48640 2Carrier Increases Energy Efficiency at Hartford Hospital 48640 3
...'s CODA® Automated EIA Analyzer is an exceptio...x microplate-based assays. The system's programmin...y laboratories. For low volume users, the software...with common features to complete 9 assays simultan...
...rent available techniques for prenatal diagnosis (... their use a small but significant chance of misca...ers invasive prenatal baby gender testing only to ...bnormalities are greater than or equal to the risk...
...SH pharmDx Kit is a direct fluorescence in situ hy...y determine HER2 gene amplification in formalin-fi...ens. Gene amplification is determined from the rat...ation of the HER2 gene probe (red signals) and the...
...ors in Anesthesia and Respiratory Products, ,West...lity medical devices for Anesthesia and Respirator...facture products that enhance the clinician's abil...lose attention to the bottom line. , ,Our web sit...
Medicine Products: