Navigation Links
Chemotherapy plus radiation prevents bladder cancer recurrences
Date:10/25/2010

Adding chemotherapy to radiation therapy for muscle invasive bladder cancer allows 67 percent of people to be free of disease in their bladders two years after treatment. This compares to 54 percent of people who receive radiation alone, according to the largest randomized study of its kind presented at the plenary session, November 1, 2010, at the 52nd Annual Meeting of the American Society for Radiation Oncology (ASTRO).

"The trial shows that this treatment offers improved control of cancer within the bladder with acceptable long-term side effects and is therefore a viable alternative to radical surgery in patients with muscle invasive bladder cancer," said Nicholas James, M.D., an oncologist at University of Birmingham in Birmingham, England, United Kingdom, who jointly led the study with Robert Huddart, M.D., from the Institute of Cancer Research in the United Kingdom. "This may shift the balance from surgery to chemo-radiotherapy as the primary treatment for many patients with invasive bladder cancer."

Bladder cancer affects about 70,000 Americans each year. It is four times more common in men than in women and two times more common in Caucasians than African-Americans. Cure rates for advanced bladder cancer are generally poor, with only around 40 percent of those with this form of the disease living more than five years after diagnosis.

In the United States, the most common treatment for advanced bladder cancer is complete removal of the bladder, which compromises patients' normal urinary function. Radiotherapy has been used as an alternative for some time. Doctors have been making advances in combining radiation therapy and chemotherapy as a way to treat bladder cancer while allowing patients an opportunity to maintain normal bladder function.

This multicenter randomized trial, conducted at 45 institutions in the United Kingdom, examined whether adding chemotherapy to radiation treatment is safe and more effective than giving radiation alone in preventing bladder cancer from returning. The trial also compared two ways of giving radiation therapy.

From August 2001 to April 2008, 458 invasive bladder cancer patients entered the trial. Results of the study show that the combination of chemotherapy and radiation treatment reduced the long-term risk of recurrence of cancer within the bladder, while also preserving bladder function.


'/>"/>

Contact: Beth Bukata
bethb@astro.org
703-839-7332
American Society for Radiation Oncology
Source:Eurekalert

Related medicine news :

1. Girls with ovarian germ-cell tumors can safely skip chemotherapy unless disease recurs
2. Women fight the effects of chemotherapy long after treatment ends
3. New lung cancer research finds half of advanced lung cancer patients receive chemotherapy
4. IU researchers: Chemotherapy alters brain tissue in breast cancer patients
5. Lung cancer survival rates improved through use of individualized chemotherapy
6. Ancient Chinese medicine may help chemotherapy patients
7. Ancient Chinese herbal recipe eases side effects of chemotherapy
8. Interruption of Menstrual Cycle by Chemotherapy Associated with Improved Survival in Early Breast Cancer
9. Making Your Way Through the Fog of Chemotherapy
10. Pregnant women can receive breast cancer chemotherapy without endangering health of their babies
11. Recommended Dental Care for Chemotherapy Patients -- Advice from Steven McConnell, DDS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2017)... ... March 29, 2017 , ... Full Contact K9, an ... Pet Protect Law that assists dog owners in creating legally-enforceable pet trusts ... in taking the natural next step to protect their new companion. Says Evan Dunbar, ...
(Date:3/29/2017)... ... 2017 , ... Youth Futures International (YFI) premiered its Serve, Learn, & Empower ... college students who have participated in the program every summer. The 2017 Serve, ... applications for enrollment. Visit http://www.ghana.yfiexperience.org to learn more. , “I have ...
(Date:3/29/2017)... , ... March 29, 2017 , ... ... several educational opportunities for attending prescribers at the upcoming World Congress, in Hollywood ... “A4M has always been recognized as the visionary leader in the training of ...
(Date:3/29/2017)... IN (PRWEB) , ... March 29, 2017 , ... ... Study, this webinar provides insight into the challenges employers face in trying to ... complexity of managing employee benefits programs? Adding to the growing complexity, companies ...
(Date:3/29/2017)... ... March 29, 2017 , ... ... it continues developing an ANSI-approved, consensus-based American National Standard for Good Manufacturing ... publish the first ANSI-approved GMP standard for dietary supplements this spring, is ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... , March 29, 2017  BioSpecifics Technologies Corp. ... continues to develop collagenase based-therapies with a first ... marketed as XIAFLEX ®  in the U.S. and ... present a corporate overview at the upcoming 16 ... April 5, 2017 at 8:00 a.m. ET in ...
(Date:3/29/2017)... -- Today, CVS Health officials (NYSE: CVS ) ... Public Health Director Gerd Clabaugh and Office of ... the availability of the opioid overdose-reversal medicine naloxone without a ... has established a standing order with physicians in ... to the medication in the state.   "Naloxone ...
(Date:3/29/2017)... -- The Global Health Innovative Technology Fund (GHIT Fund), ... infectious diseases around the globe, today announced 11 ... deliver a range of new innovative therapies for ... This latest round of targeted support includes funding ... pediatric formulation of a drug considered the gold ...
Breaking Medicine Technology: