Navigation Links
Chemotherapy before or after surgery for high-risk bladder cancer improves survival, but is not routinely administered
Date:4/14/2014

Contrary to treatment guidelines for high-risk bladder cancer, chemotherapy before or after surgery is not commonly used in routine clinical practice. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society.

Clinical trials have shown that survival is improved in patients with muscle-invasive bladder cancer who are given chemotherapy before surgery. There is less evidence about whether chemotherapy after surgery also improves survival. To investigate the use of peri-operative chemotherapy in this disease, Christopher Booth, MD, FRCPC, of the Queen's University Cancer Research Institute in Canada, examined records pertaining to all 2944 patients who had surgery for high-risk bladder cancer in Ontario between 1994 and 2008.

Use of chemotherapy before surgery remained stable (an average of 4 percent of patients) over the study period, which is surprising given the evidence that this is a standard of care that has been demonstrated to improve survival. The use of chemotherapy after surgery increased over time: 16 percent of patients in 1994 to 1998, 18 percent in 1999 to 2003, and 22 percent in 2004 to 2008. Study results showed that use of chemotherapy after surgery was associated with better survival.

"Results from our study demonstrate that chemotherapy given after surgery improves patient survivalprobably on the same order of magnitude as chemotherapy before surgery," said Dr. Booth. "Patients having surgery for bladder cancer should have chemotherapy, either before or after surgery. Efforts are needed to improve uptake of this treatment, which appears to be vastly underutilized."


'/>"/>

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
201-748-6358
Wiley
Source:Eurekalert

Page: 1

Related medicine news :

1. Adjuvant chemotherapy increases markers of molecular aging in the blood of BC survivors
2. UNC researchers show cancer chemotherapy accelerates molecular aging
3. Imprint of chemotherapy linked to inflammation in breast cancer survivors
4. Metal implants may cut chemotherapy side effects, study suggests
5. Long-term follow-up shows need for new chemotherapy strategies for rectal cancer
6. All-Organic, Odor-Eliminating Products Arrive in the Medical Marijuana Market, Helps Chemotherapy Patients Remain Free of Unwanted Smoke Odor
7. Study finds that carbon monoxide can help shrink tumors and amplify effectiveness of chemotherapy
8. Circulating tumor cells in blood can predict a patients response to chemotherapy
9. Why tumors become resistant to chemotherapy?
10. Western University cancer researcher teams up with Chinese scientists to study chemotherapy
11. Biomaterial-delivered chemotherapy could provide final blow to brain tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... 2017 , ... The Rhode Island Quality Institute (RIQI) and ... Dashboards, an innovative new service enabling healthcare providers to proactively coordinate care and ... Dashboards provide near real-time data about patients admitted to and/or discharged from acute ...
(Date:6/23/2017)... ... 23, 2017 , ... The Military Officers Association of America (MOAA) announced its ... Affairs, retired Marine Col. Thomas G. Bowman. , Bowman currently serves as the staff ... intimacy with the issues and challenges veterans face with the VA. Following a 30-year ...
(Date:6/23/2017)... ... June 23, 2017 , ... The Aesthetic Channel has recently highlighted Dr. ... come up with a proprietary technique that he calls the AuraLyft Facelift. ... For all ages, patients can expect to look refreshed, rejuvenated, and revitalized. , ...
(Date:6/23/2017)... ... June 23, 2017 , ... PureLife Dental is pleased to announce that ... CDA members. As part of the amalgam separator endorsement, all CDA members may purchase ... $400 off the retail value. This partnership between PureLife and CDA is especially timely ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... financial planning services to communities in the greater Chicago metropolitan area, is embarking ... assistance to underprivileged youth in Chicago. , Founded in 1897, Hephzibah Children’s Association ...
Breaking Medicine News(10 mins):
(Date:6/3/2017)... -- Eli Lilly and Company (NYSE: LLY ... 3 MONARCH 2 study showed that abemaciclib, a ... with fulvestrant, significantly improved progression-free survival (PFS) compared ... hormone-receptor-positive (HR+), human epidermal growth factor receptor 2-negative ... progressed after endocrine therapy (median PFS, 16.4 vs. ...
(Date:5/30/2017)... Holdings, Inc. (NYSE: HRC), will present at the Goldman Sachs ... 13, 2017, in Rancho Palos Verdes, California ... officer, is scheduled to present at 3:20 p.m. Pacific Time. ... http://ir.hill-rom.com/events.cfm . A recorded replay will be available one ... 2017. About Hill-Rom ...
(Date:5/26/2017)...  In response to the opioid epidemic in ... working with Pfizer to make up to 1 million ... community health centers, free and charitable clinics, public health ... "Pfizer has a long-standing commitment to improving health outcomes ... through educational activities," said Caroline Roan , vice ...
Breaking Medicine Technology: