Navigation Links
Chemotherapy before or after surgery for high-risk bladder cancer improves survival, but is not routinely administered
Date:4/14/2014

Contrary to treatment guidelines for high-risk bladder cancer, chemotherapy before or after surgery is not commonly used in routine clinical practice. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society.

Clinical trials have shown that survival is improved in patients with muscle-invasive bladder cancer who are given chemotherapy before surgery. There is less evidence about whether chemotherapy after surgery also improves survival. To investigate the use of peri-operative chemotherapy in this disease, Christopher Booth, MD, FRCPC, of the Queen's University Cancer Research Institute in Canada, examined records pertaining to all 2944 patients who had surgery for high-risk bladder cancer in Ontario between 1994 and 2008.

Use of chemotherapy before surgery remained stable (an average of 4 percent of patients) over the study period, which is surprising given the evidence that this is a standard of care that has been demonstrated to improve survival. The use of chemotherapy after surgery increased over time: 16 percent of patients in 1994 to 1998, 18 percent in 1999 to 2003, and 22 percent in 2004 to 2008. Study results showed that use of chemotherapy after surgery was associated with better survival.

"Results from our study demonstrate that chemotherapy given after surgery improves patient survivalprobably on the same order of magnitude as chemotherapy before surgery," said Dr. Booth. "Patients having surgery for bladder cancer should have chemotherapy, either before or after surgery. Efforts are needed to improve uptake of this treatment, which appears to be vastly underutilized."


'/>"/>

Contact: Evelyn Martinez
sciencenewsroom@wiley.com
201-748-6358
Wiley
Source:Eurekalert

Page: 1

Related medicine news :

1. Adjuvant chemotherapy increases markers of molecular aging in the blood of BC survivors
2. UNC researchers show cancer chemotherapy accelerates molecular aging
3. Imprint of chemotherapy linked to inflammation in breast cancer survivors
4. Metal implants may cut chemotherapy side effects, study suggests
5. Long-term follow-up shows need for new chemotherapy strategies for rectal cancer
6. All-Organic, Odor-Eliminating Products Arrive in the Medical Marijuana Market, Helps Chemotherapy Patients Remain Free of Unwanted Smoke Odor
7. Study finds that carbon monoxide can help shrink tumors and amplify effectiveness of chemotherapy
8. Circulating tumor cells in blood can predict a patients response to chemotherapy
9. Why tumors become resistant to chemotherapy?
10. Western University cancer researcher teams up with Chinese scientists to study chemotherapy
11. Biomaterial-delivered chemotherapy could provide final blow to brain tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... , ... April 29, 2016 , ... ... awareness for Duchenne muscular dystrophy, and funding for Duchenne research, participated in the ... of the Sarepta Therapeutic’s novel Duchenne drug eteplirsen. The meeting at the Marriott ...
(Date:4/29/2016)... ... 29, 2016 , ... Intellitec Solutions will be a sponsor ... at the Broward County Convention Center. The event is a chance for finance ... in public facility management. Intellitec Solutions will highlight their customized accounting solutions designed ...
(Date:4/29/2016)... CA (PRWEB) , ... April 29, 2016 , ... Pro3rd ... X. Utilize Pixel Film Studios’ lower thirds to introduce people, characters, and locations without ... that include boxes, lines, accents, textures and many more design components. Simply select a ...
(Date:4/29/2016)... ... April 29, 2016 , ... The number of chronically and seriously ill individuals ... there is an urgent need for highly skilled care managers and care coordinators. ... approach to train and retain care managers, and enhance their skills. , ...
(Date:4/29/2016)... PA (PRWEB) , ... April 29, 2016 , ... ... and providers, recently announced that their founders, Dr. Gemmi and Dr. Middleberg, were ... over 550 orthodontists around the nation. During the seminar, titled “Advancing the ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... , Schweiz, April 27, 2016 /PRNewswire/ ... des Sachs CEO Forums in Zürich gab ... ihres führenden Wirkstoffkandidaten STR001 zur Erhaltung des ... eingesetzt wurde, bekannt. Für die umfassende Phase-II-Doppelblindstudie ... und Frankreich angeworben. STR001 wird während der ...
(Date:4/27/2016)... Transparency Market Research has published ... Global Industry Analysis, Size, Share, Growth, Trends, and Forecast ... skincare devices market was valued at US$ 7,255.8 Mn ... CAGR of 10.1% from 2015 to 2023 to reach ... full Skincare Devices Market (Treatment Device - LED Therapy Devices, ...
(Date:4/27/2016)... Shire plc (LSE: SHP, NASDAQ: SHPG ... will present at the Deutsche Bank 41st Annual Health Care ... May 04, 2016, 10:00 am EDT (15:00 BST). ... and Webcasts section of Shire,s Investor website at http://investors.shire.com/presentations-and-webcasts/ ... on this same website for approximately 90 days. ...
Breaking Medicine Technology: