Navigation Links
Chemo-free treatment a possibility for leukemia/lymphoma
Date:3/19/2014

e across another class of drugs in my career that has been so successful for leukaemia or lymphoma."

Current therapies, such as chemotherapy, intensive chemo-immunotherapy (chemotherapy combined with immunotherapy) or stem cell transplant are effective but due to the aggressive nature of these cancers, patients always relapse and eventually run out of options.

These drugs work by inhibiting Bruton's tyrosine kinase (BTK), a protein which plays a role in the signals that cause growth in cancerous cells. Blocking this causes the cancerous cells to die but normal cells are unaffected.

With an average survival rate of four to five years, the new developments in BTK inhibiting drugs could dramatically improve the life expectancy and quality of life for patients with terminal forms of leukaemia and lymphoma who have run out of other treatment options.

David Hodge, 74, from Plymouth, was the first in the world to be treated with this new medication and more than a year on from the start of the trial is feeling the benefits.

Prior to starting the trial in September 2012, David had only several months to live. This was due to his immune system not functioning and also following years of treatment he had become resistant to all other treatments.

Professor Rule continued: "To be brutal, David had no other option. He was resistant to other forms of treatments so I am just pleased to have been able to access this drug and offer it to him."

When asked whether this was the outcome he imagined the trial to have a year ago, Professor Rule said: "I have done a lot of drug trials in my career; this drug and its predecessor, which I was fortunate to be the first person in Europe to use - they are transformational as far as I am concerned.

"So, did I expect this to happen? No, but I was hopeful that this drug would be more effective than similar drugs we could trial.

"Normally what you expect with tri
'/>"/>

Contact: Andrew Gould
andrew.gould@plymouth.ac.uk
University of Plymouth
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Sepsis study comparing 3 treatment methods shows same survival rate
2. Dartmouth researchers develop new approach to chronic lymphocytic leukemia treatment
3. Gene variants protect against relapse after treatment for hepatitis C
4. PSA-testing and early treatment decreases risk of prostate cancer death
5. Emerging multi-drug resistant infections lack standard definition and treatment
6. Making treatment of rare blood disorder more affordable and effective
7. Discoveries point to more powerful cancer treatments, fewer side effects
8. A novel treatment may reduce myocardial infarction size
9. Cancer targeted treatments from space station discoveries
10. 3-D printer creates transformative device for heart treatment
11. Editorial illustrates shift away from glycemic control in diabetes treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2015)... ... 01, 2015 , ... SuiteRx, innovative leaders in pharmacy performance ... operations, announces the most recent positioning of SuiteRx CEO, Nicholas Zener Pharm. D., ... the Venetian Las Vegas, Nevada. During this event, SuiteRx will be highlighting ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... extraction plant for Linablue®, Spirulina-derived natural blue food coloring. Construction of the plant, ... Group’s U.S. Spirulina* production base, began in May 2014. After commissioning, commercial production ...
(Date:7/1/2015)... ... ... rhinoplasty surgeon and Symposium Chairman, Dr. Rod J. Rohrich , has ... 6th - 8th, the 2016 meeting will be held at the Westin Galleria Dallas. ... surgery through the most modern advancements and updates in rhinoplasty and revision rhinoplasty ...
(Date:7/1/2015)... ... July 01, 2015 , ... During the first week of ... Training and Development) and Chuck Corso (Associate Sales Trainer) participated in the 44th ... brings together learning and development professionals from more than 300 life sciences companies ...
(Date:7/1/2015)... ... - (PRWEB) July 01, 2015 , ... Lisa Keys, the ... 5K on August 15-16th (MSG Keys’ birthday) in memory of her late husband and ... soldier and recipient of the Bronze Star Medal, died during a Special Forces training ...
Breaking Medicine News(10 mins):Health News:Pharmacy Software Vendor, SuiteRx IPS, Officially Introducing Newly Appointed CEO at Cardinal Health Event in Las Vegas, Nevada 2Health News:Pharmacy Software Vendor, SuiteRx IPS, Officially Introducing Newly Appointed CEO at Cardinal Health Event in Las Vegas, Nevada 3Health News:Pharmacy Software Vendor, SuiteRx IPS, Officially Introducing Newly Appointed CEO at Cardinal Health Event in Las Vegas, Nevada 4Health News:DIC Strengthens Its Position as the Global Leader for Natural Blue Food Coloring 2Health News:DIC Strengthens Its Position as the Global Leader for Natural Blue Food Coloring 3Health News:Dr. Rod J. Rohrich Announces Dates for 2016 Dallas Rhinoplasty Symposium 2Health News:Dr. Rod J. Rohrich Announces Dates for 2016 Dallas Rhinoplasty Symposium 3Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 2Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 3Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 4Health News:Wife of Fallen Special Forces Soldier to Host Nationwide ‘Virtual 5K’ for Charity 2Health News:Wife of Fallen Special Forces Soldier to Host Nationwide ‘Virtual 5K’ for Charity 3
... LUNG FUNCTION ,A new study shows that poor ... by several factors, including birth weight, height, and gender. Researchers ... from 252 patients, all aged 14 years. Follow-up data also ... to 51. Results showed that several factors were related to ...
... the Society of Breast Imaging (SBI) and the American ... in the January issue of the Journal of ... breast cancer screening should begin at age 40 and ... utilization of medical imaging modalities such as mammography, magnetic ...
... genitals respond differently to sexual arousal, whereas in men, ... in tune with each other, according to Assistant Professor ... her international collaborators, Michael Seto, Martin Lalumire, Ellen Laan, ... agreement between subjective ratings and physiological measures of sexual ...
... month,s Ophthalmology , the journal of the American Academy ... Vitamins C and E and magnesium on diabetic retinopathy and ... Hispanic and African-American infants and young children. ... theory, Vitamins C and E and magnesium could help prevent ...
... The fourth annual Extremity War Injuries Symposium was ... military and civilian orthopaedic surgeons, researchers, experts from governmental ... medical personnel working in Iraq and Afghanistan and to ... wounded warriors. A paper summarizing the findings from the ...
... study in the Jan. 1 issue of the journal Sleep ... with restless leg syndrome (RLS) than in those without RLS, and ... RLS symptoms. Results show that erectile dysfunction was 16 ... to 14 times per month (odds ratio of 1.16) and 78 ...
Cached Medicine News:Health News:News briefs from the January issue of Chest 2Health News:New SBI and ACR recommendations suggest breast cancer screening should begin at age 40 2Health News:Women's bodies and minds agree less than men's on what's sexy 2Health News:Update on vitamins and diabetic retinopathy; ethnic norms for preschoolers' eyesight 2Health News:Update on vitamins and diabetic retinopathy; ethnic norms for preschoolers' eyesight 3Health News:Extremity war injuries: More research is needed 2Health News:Extremity war injuries: More research is needed 3Health News:Study links restless leg syndrome with erectile dysfunction in older men 2
(Date:7/2/2015)... July 2, 2015 BGI announced today that ... Kong has been accredited by the American ... the first clinical next-generation-sequencing laboratory to receive the CAP ... highest standard in clinical laboratory practices. Complementary to the exiting ... process, and multiple ISO certifications, the CAP certification enables ...
(Date:7/2/2015)... -- Legal-Bay LLC, The Lawsuit Settlement Funding Company, announced ... in the Southern District of West Virginia ... Ethicon for a single trial to take place on ... women include claims from the women plaintiffs that they ... Johnson,s Ethicon subsidiary. The cases against Ethicon are among ...
(Date:7/2/2015)... 2015   Wilson Therapeutics AB , a privately-held ... to its board of directors. The appointment was approved ... June 30. "We are delighted to welcome ... Hansson , CEO of Wilson Therapeutics. "Hans brings significant ... forward to his contributions to the Company." ...
Breaking Medicine Technology:BGI Receives Accreditation from the College of American Pathologists (CAP) 2Judge Sets Single Trial for 26 Ethicon Mesh Cases, says Legal-Bay Lawsuit Settlement Funding 2Judge Sets Single Trial for 26 Ethicon Mesh Cases, says Legal-Bay Lawsuit Settlement Funding 3Wilson Therapeutics Appoints Hans Schikan to its Board of Directors 2
... 2011 Scientists at Osel Inc . and ... a new way to prevent HIV infection by genetically ... block viral transmission. Bioengineered bacteria introduced into the vaginal ... of simian HIV (SHIV) by nearly two thirds. ...
... July 18, 2011 Data from high-risk patients requiring ... nondeferrable, non-cardiac surgery show good short- and long-term clinical ... according to a study published online on the journal ... In the single-center study, patients treated with the Genous ...
Cached Medicine Technology:Scientists Use Live Bacteria to Fight HIV 2Scientists Use Live Bacteria to Fight HIV 3OrbusNeich's Genous™ Stent Enables Early and Safe Discontinuation of Dual Antiplatelet Therapy in High-Risk Patients Requiring Nondeferrable, Non-Cardiac Surgery 2OrbusNeich's Genous™ Stent Enables Early and Safe Discontinuation of Dual Antiplatelet Therapy in High-Risk Patients Requiring Nondeferrable, Non-Cardiac Surgery 3
... is made of Kydex and ... and back sections are adjustable ... to facilitate air circulation and ... and washable. Model C-18 is ...
... Orthosis ensures comfort and immobilization ... anterior frame and occipital component. ... flow and easy application. Large ... For added comfort, removable, flannel-covered, ...
Exo-Deluxe Overhead Traction for hospital or home care. Twice the clearance of other units between the patient and supporting wall. 2" nylon pulleys with polypropylene cord, head halter, spreader bar...
... perfect for use for lightweight padding. It ... used to line braces, prosthetics, orthotics and ... and vibration and conforms to all body ... It is a 2mm thick gel sheet ...
Medicine Products: