Navigation Links
Chemo for Mesothelioma Offers Limited Survival Benefits

Therapy does not appear to help quality of life for lung cancer linked to asbestos,,

THURSDAY, May 15 (HealthDay News) -- Adding chemotherapy to other treatments being giving to patients with mesothelioma, a lung cancer usually linked to asbestos exposure, does not appear to improve either survival or quality of life.

Malignant pleural mesothelioma (MPM), which is usually fatal, is a cancer of the protective lining that covers the lungs. Asbestos is still produced or used in large quantities in countries such as Russia, China, Canada, Kazakhstan, Brazil, Zimbabwe, India and Thailand.

In the study, published in this week's issue of The Lancet, groups of mesothelioma patients received one of two chemotherapy regimes (four cycles of mitomycin, vinblastine and cisplatin every three weeks or one injection of vinorelbine every week for 12 weeks) in addition to active symptom control (ACS) treatments. ACS can include steroids, painkillers, bronchodilators and palliative radiotherapy to control the cancer's symptoms. Another group only received the symptom control treatments.

At the time of the analysis, roughly 96 percent of patients in all three groups had died. Only a slight but statistically insignificant improvement in survival rates after one year was found when comparing the two chemotherapy groups combined to those receiving only treatment for symptoms (32 percent vs. 29 percent).

Patients in the chemotherapy group that received vinorelbine, though, did have a slightly better survival rate (37 percent) than the other two groups but, again, researchers said this was not statistically significant.

Quality-of-life scores (physical functioning, pain, shortness of breath, overall health status) were similar in the three groups.

"The addition of chemotherapy to ASC offers no significant benefits in terms of overall survival or quality of life. However, exploratory analyses suggested that vinorelbine merits further investigation," the authors concluded.

More information

The National Cancer Institute has more about mesothelioma.

-- Kevin McKeever

SOURCE: The Lancet, news release, May 15, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Targeted therapy plus chemotherapy may pack 1-2 punch against melanoma
2. Blacks not receiving chemotherapy for rectal cancer, despite seeing cancer specialists
3. Black Rectal Cancer Patients Less Likely to Get Chemo, Radiation
4. Chemotherapy causes delayed severe neural damage
5. Common Chemotherapy Drug Linked to Memory Problems
6. Drug compound leads to death of ovarian cancer cells resistant to chemotherapy
7. Karmanos Researchers Report Enhanced Chemosensitivity of Pancreatic Cancer Cells by Black Seed Component
8. High-Dose Chemo Fails Against Small Cell Lung Cancers
9. High-intensity chemotherapy does not improve survival in small cell lung cancer
10. Most Cancer Survivors Say Chemo Fears Unfounded
11. Fasting Before Chemo Protects Healthy Cells
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... ... aggressive than those found on mammography, according to a study published online in ... cancers not seen on mammography may necessitate a change in treatment. , Breast ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... offering factory direct sauna parts and accessories. , Sauna accessories help improve the ... bather’s style and personality. From basic styles for the purist looking for simplicity ...
(Date:11/25/2015)... ... November 25, 2015 , ... According to an article ... being more and more widely heralded as a breakthrough for performing hernia repairs. The ... over traditional laparoscopic surgery is that it can greatly reduce the pain that a ...
(Date:11/25/2015)... ... 25, 2015 , ... The McHenry County law firm of Botto Gilbert ... Attorneys Francisco J. Botto and Alex C. Wimmer. Attorneys Botto and Wimmer represented the ... App (2d) 130884WC. , According to court documents, Adcock testified that on May 10, ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... decades of music, friendships, and learning in its 65th Anniversary Brillianteen Revue, scheduled ... 5-6. , For 65 years, Brillianteen has been a treasured tradition ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... November 26, 2015 ... addition of the  "2016 Future Horizons ... Therapeutic Drug Monitoring (TDM) Market: Supplier ... Emerging Opportunities"  report to their offering.  ... announced the addition of the  "2016 ...
(Date:11/26/2015)... 2015 ) ... "Radioimmunoassay Market by Type (Reagents & Kits, ... Clinical Diagnostic Labs), Application (Research, Clinical Diagnostics), ... report to their offering. --> ... of the "Radioimmunoassay Market by Type ...
(Date:11/25/2015)... THOUSAND OAKS, Calif. , Nov. 25, 2015 /PRNewswire/ ... of a Biologics License Application (BLA) with ... Administration (FDA) for ABP 501, a biosimilar candidate to ... the first adalimumab biosimilar application submitted to the FDA ... biosimilar pathway. Sean E. Harper , M.D., ...
Breaking Medicine Technology: