Navigation Links
Chemo for Mesothelioma Offers Limited Survival Benefits
Date:5/15/2008

Therapy does not appear to help quality of life for lung cancer linked to asbestos,,

THURSDAY, May 15 (HealthDay News) -- Adding chemotherapy to other treatments being giving to patients with mesothelioma, a lung cancer usually linked to asbestos exposure, does not appear to improve either survival or quality of life.

Malignant pleural mesothelioma (MPM), which is usually fatal, is a cancer of the protective lining that covers the lungs. Asbestos is still produced or used in large quantities in countries such as Russia, China, Canada, Kazakhstan, Brazil, Zimbabwe, India and Thailand.

In the study, published in this week's issue of The Lancet, groups of mesothelioma patients received one of two chemotherapy regimes (four cycles of mitomycin, vinblastine and cisplatin every three weeks or one injection of vinorelbine every week for 12 weeks) in addition to active symptom control (ACS) treatments. ACS can include steroids, painkillers, bronchodilators and palliative radiotherapy to control the cancer's symptoms. Another group only received the symptom control treatments.

At the time of the analysis, roughly 96 percent of patients in all three groups had died. Only a slight but statistically insignificant improvement in survival rates after one year was found when comparing the two chemotherapy groups combined to those receiving only treatment for symptoms (32 percent vs. 29 percent).

Patients in the chemotherapy group that received vinorelbine, though, did have a slightly better survival rate (37 percent) than the other two groups but, again, researchers said this was not statistically significant.

Quality-of-life scores (physical functioning, pain, shortness of breath, overall health status) were similar in the three groups.

"The addition of chemotherapy to ASC offers no significant benefits in terms of overall survival or quality of life. However, exploratory analyses suggested that vinorelbine merits further investigation," the authors concluded.

More information

The National Cancer Institute has more about mesothelioma.



-- Kevin McKeever



SOURCE: The Lancet, news release, May 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Targeted therapy plus chemotherapy may pack 1-2 punch against melanoma
2. Blacks not receiving chemotherapy for rectal cancer, despite seeing cancer specialists
3. Black Rectal Cancer Patients Less Likely to Get Chemo, Radiation
4. Chemotherapy causes delayed severe neural damage
5. Common Chemotherapy Drug Linked to Memory Problems
6. Drug compound leads to death of ovarian cancer cells resistant to chemotherapy
7. Karmanos Researchers Report Enhanced Chemosensitivity of Pancreatic Cancer Cells by Black Seed Component
8. High-Dose Chemo Fails Against Small Cell Lung Cancers
9. High-intensity chemotherapy does not improve survival in small cell lung cancer
10. Most Cancer Survivors Say Chemo Fears Unfounded
11. Fasting Before Chemo Protects Healthy Cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
(Date:6/25/2016)... ... ... of Bruton Memorial Library on June 21 due to a possible lice infestation, as reported ... head lice: the parasite’s ability to live away from a human host, and to infest ... in the event that lice have simply gotten out of control. , As lice are ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health ... of their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards ... at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
(Date:6/24/2016)... ... , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business ... to $12 an hour by 2020 and then adjusting it yearly to increase at the ... minimum wage, assure the wage floor does not erode again, and make future increases more ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... VIEW, Calif. , June 23, 2016 ... a.m. CST on Thursday, July 7, 2016 , , , ... kayla.belcher@frost.com ) , , , , EXPERT PANELISTS:  , ... Nitin Naik; Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa ... The global pharmaceutical industry is witnessing an ...
(Date:6/23/2016)... 2016  Guerbet announced today that it has been ... Award . One of 12 suppliers to ... its support of Premier members through exceptional local customer ... commitment to lower costs. ... our outstanding customer service from Premier," says Massimo ...
(Date:6/23/2016)... June 23, 2016 The Biotechnology ... continues to present great opportunities to investors. Stock-Callers.com assesses ... Intrexon Corp. (NYSE: XON ), Vertex Pharmaceuticals ... (NASDAQ: ARNA ), and Regeneron Pharmaceuticals Inc. ... stocks and receive your complimentary trade alerts at: ...
Breaking Medicine Technology: