Navigation Links
Chemo During Pregnancy Doesn't Seem to Harm Newborn

WEDNESDAY, Aug. 15 (HealthDay News) -- Women who need chemotherapy for breast cancer during pregnancy should not compromise their treatment or deliver their babies early, a new study says.

In the study, published online Aug. 15 in The Lancet Oncology, researchers in Germany found that babies born to breast cancer patients who had chemotherapy while they were pregnant were not at greater risk for complications. They also found that the babies who did suffer from complications were premature, regardless of whether or not they were exposed to chemotherapy.

"Our findings emphasize the importance of prioritizing a full-term delivery in women who undergo chemotherapy while pregnant," study leader Sibylle Loibl, of the German Breast Group, said in a journal news release.

"Illness and mortality in newborn babies is directly related to gestational age at delivery," Loibl stressed. "This is an important clinical message because the decision to deliver the fetus preterm is often taken without medical indication. Our work suggests that treating patients with breast cancer while pregnant is possible, and there is no need to interrupt the pregnancy or receive inferior therapy."

In conducting the study, the researchers examined more than 400 European women diagnosed with early stage breast cancer while they were pregnant. Of these women, 48 percent underwent chemotherapy during their pregnancy.

The infants exposed to chemotherapy in the womb had, on average, a lower birth weight than other infants who were not exposed to the cancer drugs, the study found. The authors pointed out, however, that that was about the only noticeable difference among the babies, and the number of chemotherapy cycles the women received did not appear to affect their babies' birth weight.

Complications among the infants were more often associated with preterm delivery, regardless of exposure to chemotherapy in the womb, the researchers noted. Half of the women in the study delivered prematurely. Of these, 23 percent gave birth before they were 35 weeks pregnant. In comparison, about 10 percent to 15 percent of infants are born preterm in the general population, Loibl pointed out in the news release.

"If our findings are confirmed by other studies, breast cancer during pregnancy could be treated as it is in nonpregnant women without putting fetal and maternal outcomes at substantially increased risk," Loibl concluded.

In response to the study's findings, Dr. Olivier Mir, of the Cancer Associated with Pregnancy Network in France, said more research is needed to determine the best chemotherapy doses for pregnant women as well as the long-term risks children face from having been exposed to the cancer drugs in the womb.

More information

The U.S. National Library of Medicine has more about chemotherapy.

-- Mary Elizabeth Dallas

SOURCE: The Lancet Oncology, news release, Aug. 15, 2012

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Experimental Chemo Combo for Colon Cancer Disappoints
2. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
3. Adding drug to standard chemotherapy provides no survival benefit for older lung cancer patients
4. Chemo + Radiation Best for Bladder Cancer, Study Finds
5. Genetic predictor of breast cancer response to chemotherapy
6. Chemotherapys effect on overall survival seems to increase based on tumor size
7. Many Primary Care Docs Dont Know Long-Term Effects of Chemo: Survey
8. Accelerated chemotherapy given before surgery benefits patients with muscle-invasive bladder cancer
9. Study: Heart damage after chemo linked to stress in cardiac cells
10. Breast MRI helps predict chemotherapys effectiveness
11. Why chemotherapy fails
Post Your Comments:
Related Image:
Chemo During Pregnancy Doesn't Seem to Harm Newborn
(Date:11/29/2015)... ... , ... Key Housing, a top-rated corporate housing service for the San Jose ... Epic. In showcasing this featured apartment community in San Jose, Key Housing is helping ... efficiently find housing suitable to their needs by showcasing quality housing. , “San Jose ...
(Date:11/28/2015)... ... November 28, 2015 , ... Trying to relax on a ... COUCH BUDDY. "I conceived of this design due to personal experience with a bad ... It promotes relaxation and convenience, as well as increases support. It also makes it ...
(Date:11/27/2015)... ... ... There is only one major question facing all law firms in the ... has not been an easy question to answer. Especially when the senior partners and ... don’t share the same discipline around working long hours. , In addition to ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article ... the way that they are handling security in light of the recent terrorist attacks ... in an attempt to stop an attack from reaching U.S. soil. Especially around special ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... a safe and convenient way to dispense prescription medications at home, so he ... effective way to monitor and dispense prescription medications. In doing so, it could ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... 2015 ... "2016 Global Tumor Marker Testing Market: ... Sales Segment Forecasts, Innovative Technologies, Instrumentation Review, ... their offering. --> ) ... "2016 Global Tumor Marker Testing Market: Supplier ...
(Date:11/26/2015)... UTRECHT , Países Bajos, November 26, 2015 /PRNewswire/ ... con la terapia fotodinámica de Bremachlorin para el cáncer ... combina la inmunoterapia con la terapia fotodinámica de Bremachlorin ... Un nuevo enfoque combina la inmunoterapia con la ...   Clinical Cancer Research . --> ...
(Date:11/26/2015)... , November 26, 2015 ... new combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for ... combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced ... combination approach blends immunotherapy with Bremachlorin-photodynamic therapy for advanced ... has found that immunotherapy can be efficiently combined ...
Breaking Medicine Technology: