Navigation Links
Chemo During Pregnancy Doesn't Seem to Harm Newborn
Date:8/15/2012

WEDNESDAY, Aug. 15 (HealthDay News) -- Women who need chemotherapy for breast cancer during pregnancy should not compromise their treatment or deliver their babies early, a new study says.

In the study, published online Aug. 15 in The Lancet Oncology, researchers in Germany found that babies born to breast cancer patients who had chemotherapy while they were pregnant were not at greater risk for complications. They also found that the babies who did suffer from complications were premature, regardless of whether or not they were exposed to chemotherapy.

"Our findings emphasize the importance of prioritizing a full-term delivery in women who undergo chemotherapy while pregnant," study leader Sibylle Loibl, of the German Breast Group, said in a journal news release.

"Illness and mortality in newborn babies is directly related to gestational age at delivery," Loibl stressed. "This is an important clinical message because the decision to deliver the fetus preterm is often taken without medical indication. Our work suggests that treating patients with breast cancer while pregnant is possible, and there is no need to interrupt the pregnancy or receive inferior therapy."

In conducting the study, the researchers examined more than 400 European women diagnosed with early stage breast cancer while they were pregnant. Of these women, 48 percent underwent chemotherapy during their pregnancy.

The infants exposed to chemotherapy in the womb had, on average, a lower birth weight than other infants who were not exposed to the cancer drugs, the study found. The authors pointed out, however, that that was about the only noticeable difference among the babies, and the number of chemotherapy cycles the women received did not appear to affect their babies' birth weight.

Complications among the infants were more often associated with preterm delivery, regardless of exposure to chemotherapy in the womb, the researchers noted. Half of the women in the study delivered prematurely. Of these, 23 percent gave birth before they were 35 weeks pregnant. In comparison, about 10 percent to 15 percent of infants are born preterm in the general population, Loibl pointed out in the news release.

"If our findings are confirmed by other studies, breast cancer during pregnancy could be treated as it is in nonpregnant women without putting fetal and maternal outcomes at substantially increased risk," Loibl concluded.

In response to the study's findings, Dr. Olivier Mir, of the Cancer Associated with Pregnancy Network in France, said more research is needed to determine the best chemotherapy doses for pregnant women as well as the long-term risks children face from having been exposed to the cancer drugs in the womb.

More information

The U.S. National Library of Medicine has more about chemotherapy.

-- Mary Elizabeth Dallas

SOURCE: The Lancet Oncology, news release, Aug. 15, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Experimental Chemo Combo for Colon Cancer Disappoints
2. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
3. Adding drug to standard chemotherapy provides no survival benefit for older lung cancer patients
4. Chemo + Radiation Best for Bladder Cancer, Study Finds
5. Genetic predictor of breast cancer response to chemotherapy
6. Chemotherapys effect on overall survival seems to increase based on tumor size
7. Many Primary Care Docs Dont Know Long-Term Effects of Chemo: Survey
8. Accelerated chemotherapy given before surgery benefits patients with muscle-invasive bladder cancer
9. Study: Heart damage after chemo linked to stress in cardiac cells
10. Breast MRI helps predict chemotherapys effectiveness
11. Why chemotherapy fails
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chemo During Pregnancy Doesn't Seem to Harm Newborn
(Date:6/26/2016)... ... ... PawPaws brand pet supplements owned by Whole Health Supply is ... of felines. The formula is all-natural and is made from Chinese herbs that have ... Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root Extract ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at ... on several important health care topics including advance care planning, healthcare costs and ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... "With 30 ... their specific project," said Christina Austin - CEO of Pixel Film Studios. , ... and all within Final Cut Pro X . Simply select a ProHand generator ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. ... from injury. Recently, he has implemented orthobiologic procedures as a method for treating ... one of the first doctors to perform the treatment. Orthobiologics are substances that ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... report to their offering. ... kidney failure, it replaces the function of kidneys by removing ... thus the treatment helps to keep the patient body,s electrolytes ... Increasing number of ESRD patients & substantial healthcare expenditure ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: ... 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) assay ... sepsis or septic shock. With this clearance, Roche is ... a fully integrated solution for sepsis risk assessment and ... with bacterial infection and PCT levels in blood can ...
Breaking Medicine Technology: