Navigation Links
Chemist solves riddle of killer diseases
Date:6/23/2011

Anthrax, septicemia and meningitis are some of the planet's most deadly infections. In part because doctors lack basic insights to prevent and cure diseases caused by so called Gram-positive bacteria. Now, a chemist from the University of Copenhagen has revealed the mechanism behind these deadly infections.

By creating a synthetic version of a Gram-positive bacterial endotoxin, Danish synthetic chemist Christian Marcus Pedersen has made a contribution that'll compel immune biologists to revise their textbooks. More importantly, he has paved the first steps of the way towards new and effective types of antibiotics.

Chemist in international collaboration with biologists and physicians

The research results were attained in collaboration with Prof. Richard R. Schmidt of the University of Konstanz and biologists at the Leibniz-Zentrum fr Medizin und Biowissenschaften in Borstel, Germany. Ulrich Zhringer, leader of the Center in Borstel, is thrilled with Pedersen's achievement.

"No one knew what substance Gram-positive bacteria released to make us sick. But because Pedersen can supply us with substances that are entirely pure, and have a known structure and composition, we are able to get a more precise answer as to why we show symptoms when these bacteria enter our body," explains Professor Zhringer.

Synthesis succeeds where biologists gave up

Lipoteichoic acid, is a substance created and present in the cell wall of Gram positive bacteria. It appears to be the culprit of stimulating immune response symptoms such as fever, inflammation and organ failure. Indeed, when exploring illness, it is critical to investigate the substances that bind themselves to healthy human cells and thus, the cell wall becomes an important place to look. But if the substance breaks down as soon as it comes under the microscope, the chances of studying its binding abilities are not very great. Therefore, it was a major breakthrough when
'/>"/>

Contact: Christian Marcus Pedersen
cmp@chem.ku.dk
453-532-0190
University of Copenhagen
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Dalton Pharma Services and Boehringer Ingelheim (Canada) Ltd. Announce the Renewal of their Chemistry Services Agreement
2. Tastier MRE: Chemistry gives battlefield chow a gourmet flare
3. Subtyping breast cancer by immunohistochemistry to investigate survival terms
4. Basque researchers apply chemistry to restoration of paintings and dating of signatures
5. Pfizer joins open-access medicinal chemistry public-private collaboration
6. MIT moves toward greener chemistry
7. Biochemist studies DNA repair with $787,000 in grants
8. 2010 Chemistry Nobel laureate Ei-ichi Negishi leads C&EN webinar
9. MIT chemists engineer plants to produce new drugs
10. Medicinal chemist wins inaugural De Burgh Fellowship
11. UH biochemist works to revolutionize ovarian cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chemist solves riddle of killer diseases
(Date:4/23/2014)... internal surface area of the gastro-intestinal tract has long ... meters. Scientists at the Sahlgrenska Academy have used refined ... "Actually, the inner surface of the gastro-intestinal tract is ... scientist Lars Fndriks. , The digestive tract, which passes ... the intestines, has a length of about 5 meters ...
(Date:4/23/2014)... benefits of probiotics, antioxidants and other nutritional compounds, more ... industry is getting in on the action. But legitimate ... the industry is responding with clinical research to shore ... Chemical & Engineering News (C&EN), the weekly ... M. Bomgardner, a senior editor at C&EN, writes that ...
(Date:4/23/2014)... Parents and physicians concerned about an increase in ... can breathe a sigh of relief. According to a ... years worth of data from states with and without ... to increased use among adolescents. The study is published ... of Adolescent Health . , "Any time a ...
(Date:4/23/2014)... the bottom of Alzheimer,s disease has been a ... controversies. In the latest crook in the research ... the interaction between proteins associated with the disease. ... ACS Chemical Neuroscience , could have important implications ... Krzysztof Nieznanski and colleagues explain that for years, ...
(Date:4/22/2014)... provide primary care for low-income patients may ease ... companies while improving patient health, researchers have concluded. ... health clinics that avoid costs associated with insurance ... hospital admission rates and emergency room visits, according ... Altoona. , The researchers estimated that the ...
Breaking Medicine News(10 mins):Health News:The surface area of the digestive tract 'only' as large as a studio apartment 2Health News:RI Hospital physician: Legalizing medical marijuana doesn't increase use among adolescents 2Health News:Clinics not bogged down by red tape can ease health cost burdens 2
... HealthDay Reporter , TUESDAY, Feb. 1 (HealthDay News) ... from meningococcal meningitis, a potentially deadly infection of the ... up-to-date whooping cough vaccines in light of recent outbreaks, ... American Academy of Pediatrics issues updated vaccination guidelines annually. ...
... Society for Therapeutic Radiology and Oncology (ESTRO), the European ... for Medical Oncology (ESMO) in collaboration with other European ... on the 3rd International Conference on innovative approaches In ... on multidisciplinarity and innovation, this meeting will specifically cover ...
... Hospitals Case Medical Center and Case Western Reserve University ... addressing the lack of knowledge about causes and risk ... five-year study is funded by the National Cancer Institute ... Ovarian cancer, though relatively rare, is the most lethal ...
... for breast cancer delivers consistent rates of cancer detection and ... published online and in the April print edition of ... mammography at identifying suspicious areas of the breast, it is ... which can result in additional testing and false-positive results that ...
... charities and health organizations must tread carefully when ... risk compromise health promotion goals, states an editorial ... Journal ) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj110085.pdf . ... for health charities and organizations because they bring ...
... HealthDay Reporter , MONDAY, Jan. 31 (HealthDay News) ... stroke, they appear to have better odds of surviving one ... might seem odd since conventional wisdom says black patients typically ... in general. However, the same trend has been noticed in ...
Cached Medicine News:Health News:Pediatricians Issue New Vaccination Recommendations 2Health News:Pediatricians Issue New Vaccination Recommendations 3Health News:3rd international conference on innovative approaches in head and neck oncology 2Health News:New clinical trial to determine ovarian cancer risks in African-American women 2Health News:Repeat MRI screening for breast cancer results in fewer false positives 2Health News:Survival After Stroke Better for Blacks 2Health News:Survival After Stroke Better for Blacks 3
(Date:1/15/2014)... Jan. 15, 2014 MultiCell Technologies, Inc. (OTC Bulletin ... provisional patent application concerning composition of matter, biological targets, ... tumor cell death.  This patent application ... stranded RNA molecules (VSRNAs) which interfere with the basic ...
(Date:1/15/2014)... Jan. 15, 2014  According to Millennium Research Group ... intelligence, the United States ... markets will expand moderately through 2022, with embolization ... particular, increasing interest in drug-eluting beads (DEBs) and ...
(Date:1/15/2014)... Quebec , Jan. 15, 2014  Valeant Pharmaceuticals International, ... announced that the applicable waiting period under the Hart-Scott-Rodino ... the previously announced tender offer by its indirect wholly-owned ... outstanding shares of common stock of Solta Medical, Inc. ...
Breaking Medicine Technology:MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3
... Congressional Leaders to Introduce Legislation , WASHINGTON , ... Congressional Network (ACPCN) will join congressional leaders tomorrow to ... Savings Act." The bill by U.S. Rep. G.K. ... management (PBM) companies for medications. , "Congress is prepared ...
... AMD LASERS, the world leader in comprehensive and affordable ... Waclawik as Chief Operating Officer. In this newly created ... operations, procurement, production, quality assurance, and general financial oversight ... effort on the next-generation of product development in order ...
Cached Medicine Technology:Pharmacists Work with Congress to Address PBM Abuses 2AMD LASERS Announces the Addition of Bart Waclawik, New Chief Operating Officer 2
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medicine Products: