Navigation Links
Chemicals remaining after wastewater treatment change the gender of fish
Date:6/21/2010

Male fish that used to be feminized after chemicals, such as the pharmaceutical ethinylestradiol, made it through the Boulder, Colo., Wastewater Treatment Plant and into Boulder Creek, are taking longer to become feminized after a plant upgrade to an activated sludge process, according to a new study. The results will be presented Sunday at The Endocrine Society's 92nd Annual Meeting in San Diego.

Although the levels of the chemicals that the fish swam in were very low even before the upgrade, the chemicals are endocrine disrupters. They mimic estrogen and may disrupt the endocrine (hormone) system of both animals and humans, said the study's principal investigator, David Norris, PhD, an integrative physiology professor at the University of Colorado at Boulder.

Norris' team reported in 2006 that native male fish in Boulder Creek decreased in numbers with respect to females and numerous intersex fish were found downstream of the wastewater treatment plant. After a technology upgrade to the wastewater treatment plant in 2008, the reproductive disruption in the fish was far less pronounced. However, Norris said the study results should still concern people.

"The fish are a wake-up call," Norris said. "Our bodies and those of the much more sensitive human fetus are being exposed everyday to a variety of chemicals that are capable of altering not only our development and physiology but that of future generations as well."

With other scientists, Norris studied samples of the wastewater effluent, the plant-treated water that enters the stream and becomes another city's drinking water. Grants from the U.S. Environmental Protection Agency (EPA) and the city of Boulder supported this research.

They found other endocrine disrupters, including synthetic and natural reproductive steroids. They believe the chemicals come from natural female hormones and birth control pills excreted via urine and from detergents, cosmetics and other consumer products flushed down toilets and drains. The amount of estrogens in the sampled effluent was enough to explain the effects on the fish "downstream" from the treatment plantin the river below the plant, according to Norris. The researchers saw no signs of reproductive disruption in fish upstream.

Also, the investigators exposed adult male fathead minnows to wastewater effluent they diluted with water taken from upstream of the plant. After seven days' exposure to this water, the fish had suppressed male sex characteristics and greatly elevated levels of the protein vitellogenin. Female fish make vitellogenin under the influence of estrogens, and male fish produce very little of it, so elevated levels in males indicate estrogen exposure, Norris explained.

After the technology upgrade to the wastewater treatment plant in 2008, the effluent was considerably less estrogenic to the fish. After the treatment plant's upgrade, the minnows exhibited less intense loss of male sex characteristics, an initial analysis found. "It took 28 days to get a significant elevation in vitellogenin and then only in 100 percent effluent," Norris said. "However, these improvements seen in wildlife will not substantially lessen the risk to human health because drinking water is not the major source of estrogenic chemicals for people."


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. Chemicals that eased one environmental problem may worsen another
2. More Cancer-Causing Chemicals in U.S. Cigarettes
3. Better animal-free test for chemicals that can cause contact dermatitis
4. Prenatal Exposure to Chemicals Linked to Breast Cancer Risk
5. Natural Chemicals Act As Cancer Killers
6. Endocrine-disrupting chemicals pose cancer risk
7. Prenatal exposure to endocrine-disrupting chemicals linked to breast cancer
8. Selenium Helped Cells Reboot After Exposure to Cancer-Causing Chemicals
9. Two New Phytochemicals with Anti-Inflammatory Activity Found in Noni Fruit
10. Chemicals in Beauty Products Tied to Early Puberty in Girls
11. Exposure to 3 classes of common chemicals may affect female development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... 2017 , ... “Three Narrow Roads”: a vivid and provocative look into the ... Dr. Burnett King Sr., is currently the pastor-teacher-visionary at Simply the WORD Church, a ... Inc., a track-and-field program geared towards youth. , King shares, “When I take time ...
(Date:8/18/2017)... ... August 18, 2017 , ... Rollon Skin Care ... skincare solutions, recently announced the launch of two new skincare products, Prache ... effective alternative to expensive plastic surgery or in-patient cosmetic dermatological procedures. , “We ...
(Date:8/18/2017)... ... ... the Snake”: an entertaining and moral-based short story about an unkind snake learning a ... Jr., a husband, father and grandfather who served as a U.S. Marine, U.S. Army ... for children and teens. My goal is to teach kids to use good judgement ...
(Date:8/17/2017)... Mass (PRWEB) , ... August 17, 2017 , ... ... use by health care organizations and considered extremely effective, very effective, or effective ... Physicians and Physician Leadership”. , NEJM Catalyst Insights Reports are based on surveys ...
(Date:8/17/2017)... ... August 17, 2017 , ... Industry CEOs, life ... for Anti-Infectives Rx. This off-the-record networking forum of the Boston Biotech Conference series ... School. , Industry leaders and decision makers will discuss issues facing the development ...
Breaking Medicine News(10 mins):
(Date:8/10/2017)... -- Physical Rehabilitation Network (PRN), acquired the long-standing outpatient rehabilitation clinic, ... . The reputable clinic will continue to be co-owned and ... staff of four clinicians. Lipkin received his doctorate in physical ... years of experience with a strong background in manual therapy. ... 10th PRN clinic in and around the Denver ...
(Date:8/7/2017)... 7, 2017 Insightin Health, provider of ... and engagement, announced the selection of Michael ... Development, effective as of February 2017. In this role, ... strategy for our clients. Wood brings with him ... and business analytics within the healthcare industry. Wood ...
(Date:8/7/2017)... Pharmacy, Inc. (NYSE: DPLO), the nation,s largest independent specialty pharmacy, ...  All comparisons, unless otherwise noted, are to the quarter ended ... Second Quarter 2017 Highlights include: Revenue ... 3.5% Total prescriptions dispensed of 220,000, compared ... 7.6% Gross profit per prescription dispensed ...
Breaking Medicine Technology: