Navigation Links
Chemical liberated by leaky gut may allow HIV to infect the brain, Einstein scientists find
Date:8/18/2008

In up to 20 percent of people infected with HIV, the virus manages to escape from the bloodstream and cross into the brain, resulting in HIV-associated dementia and other cognitive disorders. Now, scientists at the Albert Einstein College of Medicine of Yeshiva University have found strong evidence that a component of the cell walls of intestinal bacteriaa chemical present in high levels in the blood of HIV-infected peoplehelps HIV to penetrate the usually-impregnable blood brain barrier (BBB). The findings, published in the August issue of the Journal of Virology, could lead to strategies for preventing HIV from entering the brain and causing serious complications.

"Previous research has suggested that it's not individual HIV viruses that get into the brain but rather HIV-infected immune cells known as monocytes," says Dr. Harris Goldstein, director of the Einstein-Montefiore Medical Center for AIDS Research and senior author of the study. "Using an animal model, we wanted to find out first of all whether being infected with HIV enables monocytes to do what they don't usually doescape from blood vessels and enter brain tissue."

Overcoming HIV's inability to infect mice, Dr. Goldstein and his colleagues had previously created a transgenic mouse line, HIV-TG mice, equipped with all the genes needed to make HIVand that produces HIV in those cells, including monocytes and T cells, in which the virus multiplies in people. The HIV-TG mice were then bred with another transgenic mouse line, GFP-TG mice, containing the gene that codes for green fluorescent protein (GFP). The result: a double transgenic mouse line, HIV/GFP-TG mice, whose HIV-infected monocytes carried the GFP gene. This meant that the monocytes could be detectedeither by looking for glowing green cells under the microscope or by using polymerase chain reaction, a sensitive genetic assay capable of detecting the DNA of the GFP gene.

Next, the researchers isolated m
'/>"/>

Contact: Michael Heller
mheller@aecom.yu.edu
718-430-4186
Albert Einstein College of Medicine
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. Black Henna Tattoo Chemical Can Cause Skin Reaction
2. Lawmakers Agree to Ban Dangerous Chemicals in Toys
3. Most Influential Events for Koreas Fine and Specialty Chemical and Pharmaceutical Industries to be Held in November
4. Stay Safe This Summer With Chemical-Free Sunscreen and DEET-Free Bug Repellent, Says Natural Solutions Magazine
5. Clean, Chemical-Free Eye Cream Evening Primrose Oil: The Puffy-Eye Cure
6. SIDS Linked to Brain Chemical Dysfunction
7. CEVA Logistics Awarded Best 3PL Provider for Pharmaceutical, Chemical, HazMat and Fresh Food Supply Chains
8. American Chemical Societys Weekly PressPac -- June 18, 2008
9. American Chemical Societys Weekly PressPac: June 11, 2008
10. UCR chemists use green chemistry to produce amines, chemical compounds used widely in industry
11. Pfizers work on penicillin for World War II becomes a National Historic Chemical Landmark
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Chemical liberated by leaky gut may allow HIV to infect the brain, Einstein scientists find
(Date:7/14/2014)... Tysons, VA (PRWEB) July 14, 2014 ... been a local icon to the Tysons Corner skyline ... Corner becoming its own municipality, known simply as “Tysons”, ... Sheraton Tysons Hotel. In addition to Tysons becoming ... Stations located in the heart of Tysons brings an ...
(Date:7/14/2014)... TX (PRWEB) July 14, 2014 Kenn Renner ... recently. The video is meant to describe the business on ... estate broker and national speaker – Kenn Renner – is ... branding, marketing, and goal setting techniques. , Investing in real ... money. Some people do it as their career, while others ...
(Date:7/14/2014)... 2014 Dry eyes, contrary to popular opinion, ... recent research have pointed out, today’s technology has practically enabled ... as a result of using laptops and smartphones to ... Because of this phenomenon, it has become imperative for people ... cure them from having dry eyes, but prevent it from ...
(Date:7/14/2014)... (PRWEB) July 14, 2014 The Cabin ... launched its new Alumni Community website – ... treatment, to help them maintain lifelong recovery wherever they ... that providing clients the tools to help them maintain ... and essential part of any reputable treatment programme. As ...
(Date:7/14/2014)... July 14, 2014 EurekaMag.com has newly ... which is a contagious liver disease that ranges ... weeks to a serious, lifelong illness that attacks the ... States have chronic Hepatitis C virus infection of which ... site's research category covers all studies on Hepatitis ...
Breaking Medicine News(10 mins):Health News:Iconic Tyson’s Corner Hotel Embraces the New “Tysons” Evolution 2Health News:Iconic Tyson’s Corner Hotel Embraces the New “Tysons” Evolution 3Health News:Iconic Tyson’s Corner Hotel Embraces the New “Tysons” Evolution 4Health News:Dry Eye Handbook Review | Taking Care of One’s Vision by Using Natural Methods – Vinamy.com 2Health News:Dry Eye Handbook Review | Taking Care of One’s Vision by Using Natural Methods – Vinamy.com 3Health News:The Cabin Chiang Mai Addiction Rehab Launches Industry-leading Aftercare Service 2Health News:The Cabin Chiang Mai Addiction Rehab Launches Industry-leading Aftercare Service 3Health News:EurekaMag.com Publishes 64,900 New Studies on Hepatitis C 2
... off from certain osteoporosis drugs may be beneficial to bone ... System. Researchers found that bone density remained stable for three ... a popular class of osteoporosis drugs that can cause fractures ... bone. "These drugs are potentially harmful when taken for ...
... By Randy Dotinga HealthDay Reporter , THURSDAY, Nov. ... evidence that people infected with HIV, the virus that causes ... other patients when they undergo kidney transplants. Up until ... HIV patients because of fear that AIDS would quickly kill ...
... Johns Hopkins have identified a compound that could be ... The compound, called a glutaminase inhibitor, has been ... scientists say, may have the potential to be used ... Johns Hopkins scientists, are inventors on patent applications related ...
... NC Researchers have been stymied for years over the ... produce antibodies in response to the pathogen antibodies that ... at Duke University Medical Center can explain why: Some of ... can,t actually "see" the virus until after it,s already invaded ...
... THURSDAY, Nov. 18 (HealthDay News) -- Millions of harried ... indoor smoking at one in every four major U.S. ... smoke-free policies at large-hub airports in 2002 and 2010 ... nation,s largest airports, including three of the five busiest: ...
... Reinberg HealthDay Reporter , WEDNESDAY, Nov. 17 (HealthDay ... example, new research finds that doctors, prescribing patterns vary across ... U.S. Food and Drug Administration. The result is ... depending on where they live, the researchers said. "We ...
Cached Medicine News:Health News:Taking a break from osteoporosis drugs can protect bones 2Health News:HIV Patients Do Well After Kidney Transplants: Study 2Health News:HIV Patients Do Well After Kidney Transplants: Study 3Health News:Compound that blocks sugar pathway slows cancer cell growth 2Health News:Compound that blocks sugar pathway slows cancer cell growth 3Health News:Why so many antibodies fail to protect against HIV infection 2Health News:Smoking Still Allowed at 1 in 4 Major U.S. Airports 2Health News:Despite FDA Warning, Avandia Use Varies Across U.S. 2Health News:Despite FDA Warning, Avandia Use Varies Across U.S. 3
(Date:7/11/2014)... , July 11, 2014  Australian drug delivery ... that it has raised A$19.3 million via a placement ... Europe , the U.S., Asia ... million from a share purchase plan (SPP) to be ... will be made in two tranches. "This ...
(Date:7/11/2014)... July 11, 2014 According to ... "Endoscopy Devices Market (Endoscopes, Endoscopic Operative Devices, and Visualization ... and Forecast, 2013-2019" the global endoscopy devices market was ... expected to grow at a CAGR of 6.8% from ... USD 36.9 billion in 2019. Browse the ...
(Date:7/11/2014)... , July 11, 2014  Veran Medical ... announced today the positive, cost-effective final results ... SPiNPerc™ procedure. The SPiNPerc endobronchial percutaneous biopsy ... percutaneous approach to biopsy when a traditional ... and physicians experience positive financial outcomes when ...
Breaking Medicine Technology:Phosphagenics' A$19.3 million Capital Raising 2Phosphagenics' A$19.3 million Capital Raising 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6Veran Medical Publishes Lung Cancer Patient Management Study 2
MediNotes e is an EMR design which utilizes a "tab concept for navigation. MediNotes e can display multiple patients, encounter notes, workflow items, patient flow, messages, alerts, and more, all in...
... Pro Software developed a touchscreen EHR and ... While a user can choose to use ... to maintain eye contact while recording encounter ... Pro EHR also runs on a pen ...
... Anasazi Clinicians HomePage is a comprehensive on-line ... helps you by reducing your time and ... to concentrate on the clients quality of ... completes a chart audit and shows you ...
... The GE RecordsTFC System ... Registration and other patient/resident record ... approach. It supports multiple facilities ... outpatient and ambulatory clinics, community ...
Medicine Products: