Navigation Links
Cheaper, Older Treatment for Vasculitis Beats Out New Drug
Date:11/8/2010

MONDAY, Nov. 8 (HealthDay News) -- New research suggests that a newer drug works no better than an older, cheaper medication for patients who need long-term treatment for a type of vasculitis, a rare blood vessel disorder.

The older drug, azathioprine, "beat out the new kid on the block," said Dr. Ronald Falk, a kidney specialist familiar with the findings. But that's not necessarily good news because relapses and serious side effects are common over time.

Vasculitis strikes about one in every 100,000 people, Falk said. An overly aggressive response by the immune system causes the blood vessels of the body to swell, creating problems in the kidneys and lungs.

Azathioprine (Azasan) is currently used for long-term treatment of patients with a form of the disease known as antineutrophil cytoplasmic antibody-associated vasculitis.

The new study compares the drug to another medication, mycophenolate mofetil (CellCept), which dampens the immune system and is used in organ transplant patients.

The study, which is to be presented Monday at the American College of Rheumatology's annual meeting in Atlanta, will appear in the Dec. 1 issue of the Journal of the American Medical Association.

Researchers, led by Dr. Thomas F. Hiemstra of the University of Cambridge in England, randomly assigned 156 patients in Europe to receive one of the two drugs. Patients were more likely to relapse on the newer drug. Both drugs had about the same level of severe side effects, the researchers reported.

"Although mycophenolate mofetil is frequently regarded as a potent alternative to azathioprine, we found no evidence to support its use as the initial remission maintenance therapy for patients with AAV," the researchers said in a news release from the journal.

"The issue of how to maintain remission is critically important. At least now these patients can take a less expensive drug that seems to work better," said Falk, director of the University of North Carolina Kidney Center at Chapel Hill.

More information:

For more about vasculitis, try the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCE: American Medical Association, press release, Nov. 8, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Watch your step: Elevator-related injuries and older adults
2. California IVF Discount/Rebate Program Eases Risk for Older Mothers
3. Diabetes drug ups risk for bone fractures in older women
4. Autism Science Foundation Offers IMFAR Grants to Autism Stakeholders
5. Americans Recognize Risk of Fire to Older Adults
6. Key Pillars of Patient Centered Medical Home Will Be Focus of March 30 Patient-Centered Primary Care Collaborative Stakeholders Meeting
7. Kidneys From Older Donors Suitable for Seniors
8. Screens, Vaccine for HPV Less Beneficial in Older Women
9. Tyco International to Host 2010 Annual General Meeting of Shareholders
10. Midlife crisis: Unmarried older women twice as likely to lack health insurance, study shows
11. New clues found linking larger animals to colder climates
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cheaper, Older Treatment for Vasculitis Beats Out New Drug 
(Date:2/24/2017)... ... February 24, 2017 , ... With ProGlass Prism users now have the ability ... total control over position, rotation, distortion, edge softness, edge blur, chromatic aberration, individual glass ... , With ProGlass Prism users are given the tools and effects to generate ...
(Date:2/24/2017)... ... February 24, 2017 , ... The Radiology Business Management Association ... marketing programs at the annual Building Better Radiology Marketing Programs conference, held ... in Fort Worth, Texas. Nine awards are given out in five categories. They are:, ...
(Date:2/23/2017)... , ... February 23, 2017 , ... ... of Justice jointly issued a letter to withdraw previous guidance issued ... their gender identity. The guidance issued in May 2016 by the Obama Administration ...
(Date:2/23/2017)... Angeles, CA (PRWEB) , ... February 23, 2017 , ... ... first two episodes of WE TV’s “Mama June: From Not to Hot,” which will ... TV notable, “Mama” June Shannon, known to millions from the 2012 reality television series, ...
(Date:2/23/2017)... ... February 23, 2017 , ... Dr. David Mahon leads Siena Dental, a comprehensive ... was named a 2017 Top Patient Rated Henderson Dentist by Find Local ... recognizes local physicians and dentists who have earned high ratings and superior patient reviews ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Feb. 24, 2017  Xynomic Pharmaceuticals, Inc., an ... that it has acquired exclusive worldwide rights to ... innovative HDAC inhibitor targeting hematological and solid tumors. ... Phase 1 and 2 clinical trials of Abexinostat ... have already been completed, demonstrating that Abexinostat ...
(Date:2/23/2017)... Feb. 23, 2017  Genesis Healthcare Services has merged ... was made by Bill Monast , President and ... and Nathan Feltman , executives with Home Health ... LLC. This acquisition helps Hospice Cloud ... technology enabled durable medical equipment (DME) solutions for the ...
(Date:2/23/2017)... REDWOOD CITY, Calif., Feb. 23, 2017 Nevro Corp. ... innovative evidence-based solutions for the treatment of chronic pain, today ... ended December 31, 2016. 2016 Accomplishment & ... the full year 2016, an increase of 228% as reported, ... million for 2016, an increase of 612% over the prior ...
Breaking Medicine Technology: