Navigation Links
Changing epidemiology of rare disease links sinus irrigation with contaminated tap water, 2 deaths
Date:8/22/2012

[EMBARGOED FOR AUG. 23, 2012] When water containing the Naegleria fowleri ameba, a single-celled organism, enters the nose, the organisms may migrate to the brain, causing primary amebic meningoencephalitis, a very rarebut usually fataldisease. A new study published in Clinical Infectious Diseases describes the first reported cases in the United States implicating nasal irrigation using disinfected tap water in these infections. Now available online, the study highlights the changing epidemiology of this uncommon disease, as well as the importance of using appropriately treated water for nasal irrigation.

From 2002 to 2011, 32 N. fowleri infections were reported in the U.S., according to the Centers for Disease Control and Prevention (CDC). In this latest study, Jonathan Yoder, MPH, coordinator of waterborne diseases and outbreak surveillance at CDC, reports the work of the Louisiana Department of Health and Hospitals and CDC in investigating two cases in 2011 in Louisiana. Two unrelated patients, a 28-year-old man and a 51-year-old woman, each died within five days of being admitted to the hospital with meningitis-like symptoms. Both had used a neti pot for regular sinus irrigation. Because family members of both patients were certain the patients had no recent history of recreational freshwater contact, which is typically associated with the disease, sinus irrigation using disinfected (chloraminated) tap water was implicated.

"N. fowleri was found in water samples from both homes," Yoder said, but "not found in the treatment plants or distribution systems of the municipal water systems servicing the patients' homes." Although it was never clear how N. fowleri were introduced into the plumbing of the patients' houses, once there, the organisms were able to colonize the hot water systems.

In addition, Yoder's team also tested commercially available reconstituted salt packets for use with neti pots and found that these were unable to reduce the number of N. fowleri organisms within a four-hour timeframefar outside the real world conditions of less than a minute that most people spendshowing that simply adding salt mixtures to tap water does not inactivate the organisms fast enough. As a result, Yoder advises that the simplest methods to avoid infection is to purchase water that is labeled as distilled or sterile, or use only water that was previously boiled for 1 minute (at elevations above 6,500 feet, boil for 3 minutes) that has been left to cool, or use water that has gone through a filter with a pore size of 1 micron or smaller.

Many infections from N. fowleri occur in warm freshwater locations following localized heat waves. Whether projected climate change could lead to an expansion of the ameba's geographic range is unknown, the authors noted. They recommend that systematic environmental sampling be carried out to document changes in the ecology of N. fowleri so that measures to prevent its spread can be improved. It is also important to raise the level of awareness about the disease among physicians treating patients with meningitis-like symptoms, the authors wrote.

Deaths from N. fowleri infection, which remain very rare, "are tragic for the families of those infected," Yoder said. "The CDC is working to understand this organism so that we can improve prevention recommendations, identify N. fowleri infections, and improve clinical treatment."

Fast Facts

  1. Primary amebic meningoencephalitis is a very rare but usually fatal disease caused when water containing Naegleria fowleri amebae enters the nose, allowing the single-celled organisms to migrate to the brain.
  2. In 2011, two fatal cases of the disease reported from Louisiana occurred in persons following nasal irrigation. This is the first time that contaminated tap water coming from a disinfected municipal water system has been linked to N. fowleri infections in the United States.
  3. For prevention, health officials advise using only previously boiled, filtered, distilled, or sterilized water when making solutions for irrigating, flushing, or rinsing the sinuses.


'/>"/>

Contact: Laurel White
lwhite@pcipr.com
312-558-1770
Infectious Diseases Society of America
Source:Eurekalert

Related medicine news :

1. Brain structure helps guide behavior by anticipating changing demands
2. Birds Songs Reflect Changing Weather Patterns: Study
3. Witnessing, Experiencing Traumatic Events May Worsen Heart Disease
4. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
5. Mayo Clinic offers newly approved treatment for acid reflux disease
6. Spouses of Cancer Patients May Have Raised Risk of Heart Disease, Stroke
7. Huntingtons Disease Linked to Reduced Cancer Risk in Study
8. AstraZeneca and DNDi to collaborate on drug screening for neglected tropical diseases
9. Role of Screening, Monitoring in Early Kidney Disease Unclear
10. No Proof That Gum Disease Causes Heart Disease, Experts Say
11. 19th century therapy for Parkinsons disease may help patients today
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... ... September 22, 2017 , ... Global ... diseases through research, education and awareness, today announced the appointment of Timothy J. ... microbiologist, Dr. Sellati has more than 20 years of research experience with Lyme ...
(Date:9/21/2017)... ... September 21, 2017 , ... SABRE is raising awareness about personal ... to the end of November. , The Chicago, Illinois, based self-defense brand has been ... them about the ease of taking their personal safety into their own hands. , ...
(Date:9/21/2017)... Virginia (PRWEB) , ... September 21, 2017 , ... ... health in their communities, nine governmental public health departments have been awarded five-year ... accreditation decisions mean that the benefits of being served by a PHAB-accredited ...
(Date:9/21/2017)... ... September 21, 2017 , ... The New England Center for Children® ... the election of Yie-Hsin Hung to the Board of Directors. , “The New ... Directors. Ms. Hung is an invaluable addition to our team,” said Vincent Strully, Jr., ...
(Date:9/21/2017)... ... ... FlipBelt, the fitness brand that specializes in problem solving fitness accessories, has ... the launch of their FlipBelt Crops. , The new fitness bottoms feature an integrated ... at the gym, on the trail, or on-the-go. , “We always thought the FlipBelt ...
Breaking Medicine News(10 mins):
(Date:9/9/2017)... Sept. 8, 2017 Dealmed Medical Supplies, ... of medical equipment, supplies, drugs, vaccines, and specialty medical ... into an agreement to acquire Vantage Medical Supplies, a ... Holtsville, New York . ... new and emerging medical practices, will operate under the ...
(Date:9/7/2017)... Sept. 7, 2017  Eli Lilly and Company ... to streamline operations to more efficiently focus resources ... cost structure. Global workforce reductions, including those from ... to impact approximately 3,500 positions. ... annualized savings of approximately $500 million that will ...
(Date:9/7/2017)... , Sept. 7, 2017 Caris ... focused on fulfilling the promise of precision medicine, ... validate the benefits of its molecular profiling approach ... utilized comprehensive genomic profiling plus (CGP+) with Caris ... patient,s tumor on a molecular level, leading to ...
Breaking Medicine Technology: