Navigation Links
Changes Reduced Infections From Medical Abortion
Date:7/8/2009

Differences in drug use, delivery made a measurable impact in Planned Parenthood study

WEDNESDAY, July 8 (HealthDay News) -- Two changes to the way Planned Parenthood clinics perform medical abortion resulted in a 93 percent drop in the rate of serious infections, a new report says.

The changes involved administering the drug misoprostol to the area between the gum and the cheek (buccal administration), not the vagina, and introducing routine treatment with antibiotics.

"Planned Parenthood is very happy with the regimen," said Mary Fjerstad, lead author of a paper appearing in the July 9 issue of the New England Journal of Medicine.

"We've got the same head-to-head efficacy as with vaginal delivery and a significant reduction in infections. And, since we added antibiotics, we have a further drop in serious infections," added Fjerstad, a nurse practitioner who was director of clinical quality improvement at the Planned Parenthood Federation of America when the study was conducted. She is now a senior clinical advisor at Ipas, a nonprofit organization in El Cajon, Calif., dedicated to increasing women's sexual and reproductive rights.

Some 300 Planned Parenthood clinics in the United States provide medical abortion, which is an abortion induced by medication rather than surgery.

There are three methods of medical abortion: misoprostol alone; methotrexate followed by misoprostol; and mifepristone (the so-called "abortion pill") followed by misoprostol. The combination of mifepristone and misoprostol is the most commonly used method. Mifepristone received approval from the U.S. Food and Drug Administration for use in medical abortion in 2000.

From 2001 to March of 2006, Planned Parenthood health clinics generally provided medical abortions with a combination of mifepristone, given orally, followed 24 to 48 hours later with misoprostol administered vaginally.

Prior research had shown that the combination was successful in inducing abortions in 98.5 percent of cases.

But in 2005, authorities reported the deaths of five North American women from an otherwise rare bacterial infection -- Clostridium sordellii -- within a week of taking mifepristone.

In 2006, Planned Parenthood substituted buccal misoprostol for vaginal misoprostol along with either antibiotics or screening and treatment for chlamydia, a sexually transmitted bacteria.

The following year, the organization started requiring antibiotics for all medical abortions. Antibiotics have been shown to reduce infection rates after an abortion by 42 percent, the report said.

The authors reviewed the rate of serious infections after medical abortions in more than 227,000 women, comparing the risk in women to whom misoprostol was given vaginally (up to March 2006) with those who received buccal administration in concert with antibiotics.

The rate of serious infections dropped 73 percent from 0.93 per 1,000 abortions before introduction of buccal administration along with antibiotics or STD screening to 0.25 per 1,000 abortions after the switch, the researchers found. Adding antibiotics to the protocol dropped the rate of serious infections a further 76 percent.

The findings in this paper essentially validate Planned Parenthood's recent changes, Fjerstad said.

"Unless there was compelling evidence to the contrary, we just don't see any reason to make a change," she said.

Wendy Wright is executive vice president of Concerned Women for America, an organization that opposes abortion.

"This study…shows that the RU-486 [mifepristone] and misoprostol regimen can still cause serious complications to patients," Wright said. "While taking misoprostol orally rather than vaginally may reduce the risk, it does not eliminate consequences."

More information

For more on medical and surgical abortion, visit the University of California, San Francisco.



SOURCES: Mary Fjerstad, N.P., M.H.S., senior clinical advisor, Ipas, El Cajon, Calif.; Wendy Wright, executive vice president, Concerned Women for America, Washington, D.C.; July 9, 2009, New England Journal of Medicine


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Arbios Announces Management Changes
2. Renovis Announces Management Changes
3. Bradmer announces management changes
4. Streamline Health Announces Executive Management Changes
5. Onyx Pharmaceuticals Announces Management Changes
6. How pitching changes little leaguers shoulders
7. Sontra Medical Corporation Changes Name to Echo Therapeutics, Inc.
8. Medicare Changes Didnt Alter Cancer Care
9. Breaking Study: Masimo Pleth Variability Index (PVI) Shown Effective in Noninvasive Detection of Changes in Ventricular Preload and Fluid Volume
10. HealthShares(TM) Announces Changes to the HealthShares(TM) Diagnostics and Composite Indexes
11. Imaging shows structural changes in mild traumatic brain injury
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Changes Reduced Infections From Medical Abortion 
(Date:3/24/2017)... ... March 24, 2017 , ... As the standards bearer ... communications platform that positions them as the go-to thought leader in all matters ... publication as an always-on, always-fresh news, views and advocacy engine, called ONS Voice. ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... ) announced their partnership to prep patients for colonoscopy at the HyGIeaCare® Center ... in 87th Ave., Miami, FL. , The HyGIeaCare® Prep, cleared by ...
(Date:3/24/2017)... ... ... “Vintage and Harvest A Cultivation of Christian Love” is the creation of ... Carolina with his wife, Anna Marie. He and his wife are the proud parents ... the author of “Shadow and Substance.” , “Love, the agape kind, is seen as ...
(Date:3/23/2017)... ... ... The physicians of KSF Orthopaedic Center PA are proud to announce the ... located at 2255 E. Mossy Oaks Rd., Suite 440, Spring, Texas 77389 inside the ... living in the north Houston area (The Woodlands, Conroe, Magnolia, Kingwood, Humble) with an ...
(Date:3/23/2017)... Grimsby, Ontario (PRWEB) , ... March 23, 2017 , ... The MBI “Hall of Fame” ... or whose acts have had a significant impact on the careers of all others involved. ... with NRB Inc. was inducted into the MBI’s Hall of Fame. The induction took ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , Mar 24, 2017 The Board ... the company,s Annual Report 2016 including the complete 2016 Annual ... and available on Nordic Nanovector,s website in the section Investor ... ... IR enquiries: Tone Kvåle, Chief Financial Officer Cell: +47-91-51-95-76 Email: ...
(Date:3/23/2017)... March 23, 2017  Transportation Insight, a multi-modal lead ... supply chain management firm with expertise serving clients in ... Rick Zaffarano was named a 2017 ... Chain by the only publication exclusively dedicated to covering ... chain. "Rick has brought to Transportation Insight ...
(Date:3/23/2017)... Summary Global ... guide Primary Hyperoxaluria - Pipeline Review, H1 2017, ... Urinary System And Sex Hormones) pipeline landscape. ... recurrent kidney and bladder stones. It results from ... include blood in the urine, pain when urinating, ...
Breaking Medicine Technology: