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ChanTest Announces a Global Campaign to Share New Findings and Developments in Cystic Fibrosis (CF) Research
Date:8/14/2014

Cleveland, OH (PRWEB) August 14, 2014

With over 70,000 people suffering from cystic fibrosis (CF) worldwide, and 30,000 alone in the United States, the world is searching for impactful solutions to address the pain and suffering endured by people living with this debilitating disease.

To this end, ChanTest has announced a global campaign to share new findings and developments in CF research through the publication of a new, cutting-edge white paper entitled “Unfolding Cystic Fibrosis Research”. As a leader in supporting the drug discovery and development industry, ChanTest has played a crucial role in progressing our worldwide understanding on how to solve critical CF challenges.

Cystic fibrosis causes the creation of a thick and sticky mucus, which clogs important organs such as the lungs or the digestive system. CF is caused by a mutation in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Although there are over 1000 mutations that produce this disorder, the most common is the deletion of phenylalanine at position 508 of the CFTR protein (CFTR F508del). This results in the production of misfolded CFTR protein that is then rarely inserted into the cell membrane, where it belongs.

Nearly 90% of the CF population has at least one copy of the F508del mutation, which is why ChanTest focuses their research, and has produced this white paper, with an emphasis on ‘Unfolding’ cystic fibrosis.

The white paper not only focuses on the role of this important protein, but also discusses many scientific assay projects which have the potential to significantly affect those with cystic fibrosis. This testing and analysis, supported by assay work conducted by ChanTest, helps to show what methods, and therefore what drugs, are most effective in treating this disorder and its symptoms.

According to Dr. Anthony Lacerda, Director of Contract Research and Development a
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