Navigation Links
Champions Biotechnology signs exclusive agreement with Tel Aviv University for cancer drug
Date:12/2/2009

Champions Biotechnology, Inc. (OTC Bulletin Board: CSBR), a U.S. Oncology drug development company with a predictive preclinical platform aimed at accelerating the development and enhancing the value of oncology drugs, has established an exclusive licensing agreement with Ramot at Tel Aviv University Ltd., Tel Aviv University's wholly owned technology transfer company.

The licensing agreement encompasses the development and commercialization of TAR-1, a single-chain antibody fragment in preclinical development that may have an advantage in treating cancer patients because of its high specificity and affinity to binding mutant p53 protein.

Under the terms of the agreement, Champions has obtained the worldwide rights to TAR-1 and is responsible for the further development of the compound. Champions will utilize its Biomerk Tumorgraft(TM) platform technology to evaluate the activity of TAR-1 and determine the best path forward for the compound in regards to indication, patient population and potential drug combinations. Ramot will receive an upfront payment and will be eligible to receive milestone payments and royalties if Champions chooses to continue the license terms, which will be determined based on results from testing TAR-1 in the predictive Tumorgraft platform.

Inhibits tumor growth

Prof. Beka Solomon from Tel Aviv University identified that TAR-1 binds to and restores the wild-type active conformation of mutant p53 protein with a high degree of specificity, leading to in vivo inhibition of tumor growth. Given the frequency of mutant p53 in cancer, TAR-1 has the potential to target a wide range of human cancers.

"Licensing TAR-1 demonstrates the progression of our strategy to build our own Tumorgraft-driven pipeline of oncology drugs, which we expect to yield improved clinical development success rates," said Guy Malchi, Champions Biotechnology's Head of Corporate Development and International O
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

0

GOOD

Page: 1 2

Related medicine news :

1. Houston Dermatologists to Round Up for Sun Safety at World-Class LPGA Tour Championship
2. World Champion New York Yankees, BNY Mellon to be Honored as New York Blood Center Champions of Life
3. Planned Parenthood Advocacy Project Los Angeles County Celebrates Champions of Choice at Politics, Sex & Cocktails
4. Maldonado Medical LLC Champions Physician & Patient Rights for Better Reimbursement Schedules Nationwide
5. Illinois Dermatologists Tee Up for Sun Safety at Two World-Class Golf Championships
6. Mentors Who Support Students Receive TCWF Champions of Health Professions Diversity Award
7. The Byron Nelson: Championship Philosophy, Timeless Excellence
8. Champions Shawn Johnson & Phil Jackson Wear Energy Muse Jewelry
9. The Biggest Loser Champions Living Well
10. Insulet Applauds Employee for Bronze Medal Performance in World Blind Sailing Championships
11. The National Multiple Sclerosis Societys 35th Annual Dinner of Champions to Honor Summit Entertainments Rob Friedman
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Champions Biotechnology signs exclusive agreement with Tel Aviv University for cancer drug
(Date:5/23/2013)... , , THURSDAY, May 23 (HealthDay News) -- Glucosamine supplements ... and knee osteoarthritis may have an unexpected side effect: ... new study of older adults suggests. Glaucoma ... (IOP) or pressure inside the eye. Left untreated, glaucoma ... In the new study of 17 people, ...
(Date:5/23/2013)... -- A modified version of the polio virus ... research suggests. Scientists at Duke Cancer Institute ... uses an engineered form of the virus that ... cells. The therapy shows promise in the treatment ... tumor, they said. "These early results are ...
(Date:5/23/2013)... (HealthDay News) -- People who eat at fast-food restaurants ... and teens are the worst offenders, a new study ... their meals by as much as 34 percent, parents ... and adults by as much as 20 percent," study ... release from the Robert Wood Johnson Foundation, which helped ...
(Date:5/23/2013)... Memorial Day Focus Spotlight on Military ... a part of the U.S. Military for more than ... it, these men and women will be honored for ... America. As veterans transition to civilian life, there ... workplace chaplaincy world. , Marketplace Chaplains, America’s original ...
(Date:5/23/2013)... (May 23, 2013)Don,t doubt it when a woman harried ... remembering things. A new study published online in ... Society (NAMS), helps confirm with objective tests that what ... In the past, some studies showed that hot flashes ... studies showed that, even though there was a relationship ...
Breaking Medicine News(10 mins):Health News:Glucosamine Supplements Tied to Risk of Eye Condition 2Health News:Glucosamine Supplements Tied to Risk of Eye Condition 3Health News:Modified Polio Virus May Help Fight Brain Tumors, Study Suggests 2Health News:How Many Calories in Your Fast-Food Meal? Guess Again 2Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 2Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 3
... May 26, 2010 Complete Genomics Inc., a third-generation ... a wholly owned member of the Roche Group (SIX: ... and analytics services to sequence and compare a patient,s ... like this allow researchers to compare the patient,s genome ...
... amounts in the gums, those tough pink tissues that hold the ... to develop an early, non-invasive test for gum disease, the No. ... quart of which people produce each day, but gingival crevicular fluid ... tooth. The study, the most comprehensive analysis of GCF to date, ...
... People undergoing bisphosphonate therapy to prevent or treat osteoporosis (a ... and possible adverse side effects on oral health, according to ... of the American Dental Association (JADA). , Use of ... bisphosphonate-associated osteonecrosis of the jaw (BON) that occurs spontaneously or ...
... ... at over 3,000 retail sites. , ... (PRWEB) May 26, 2010 -- Buckts Firefox Add-on delivers discounts and ... purchase. When a shopper visits an online retailer, clicking on the highlighted ShoppingBuckt ...
... ... $100,000 per-violation penalties , ... Alexandria, VA (Vocus) May 26, 2010 -- More than ten major retailers, representing ... offered by the National Association of Chain Drug Stores (NACDS) and RollStream. ...
... expected changes to oversight of supplement industry , WEDNESDAY, ... dietary herbal supplements has found trace amounts of lead, ... tested, plus myriad illegal health claims made by supplement ... , The levels of heavy metal contaminants did not ...
Cached Medicine News:Health News:Genentech uses Complete Genomics' human genome sequencing service to compare tumor and normal genome in patient with non-small cell lung cancer; results published in Nature 2Health News:Some bisphosphonates users unfamiliar with drug's possible side effects on oral health 2Health News:Retailers and Manufacturers Quickly Adopt Online Network to Address CPSIA Compliance 2Health News:Retailers and Manufacturers Quickly Adopt Online Network to Address CPSIA Compliance 3Health News:Many Supplements Said to Contain Toxins, Make False Health Claims 2
(Date:5/23/2013)... RIVER EDGE, N.J. , May 23, 2013 /PRNewswire/ ... ), a commercial stage medical device company that develops ... the successful completion of its rights offering.  In addition, ... company,s March 2011 warrants expired on May 17, 2013. ... proceeds of $3.0 million from the rights offering.   A ...
(Date:5/23/2013)... , May 23, 2013  A recently published ... Houston, Texas , demonstrates that 3D ... increasing cancer detection. The study, "Implementation ... Observational Study," was led by Stephen L. ... issue of the American Journal of Roentgenology ...
(Date:5/23/2013)... IRVINE, Calif. , May 23, 2013 ... breast cancer may not benefit from chemotherapy and still ... announced the launch of one of the largest sources ... The new website and interactive Facebook page provide recently ... if they can safely avoid chemotherapy. "We ...
Breaking Medicine Technology:Nephros Announces Completion of Rights Offering 2Nephros Announces Completion of Rights Offering 3Nephros Announces Completion of Rights Offering 4First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 2First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 3Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 2Agendia Launches Social Media Campaigns to Help Breast Cancer Patients with Chemotherapy Decisions 3
... CeloNova BioSciences, Inc.,("CeloNova"), leading and accelerating ... innovative medical devices, has released data,from THE ... study of uterine fibroid,embolization using the Company,s ... the 20th Annual International Symposium on,Endovascular Therapy., ...
... Disease Indication for HUMIRA Provides Patients with Visible, ... Chronic Autoimmune Disease, ABBOTT PARK, Ill., Jan. ... it has received U.S. Food and Drug Administration ... for adult patients,with moderate to severe chronic plaque ...
Cached Medicine Technology:CeloNova BioSciences Announces Positive Results from European Study of Embozene(TM) Microspheres for Treatment of Uterine Fibroids 2Abbott's HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis 2Abbott's HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis 3Abbott's HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis 4Abbott's HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis 5Abbott's HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis 6Abbott's HUMIRA(R) (adalimumab) Receives FDA Approval For Moderate to Severe Chronic Plaque Psoriasis 7
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: