Navigation Links
Champions Biotechnology signs exclusive agreement with Tel Aviv University for cancer drug
Date:12/2/2009

Champions Biotechnology, Inc. (OTC Bulletin Board: CSBR), a U.S. Oncology drug development company with a predictive preclinical platform aimed at accelerating the development and enhancing the value of oncology drugs, has established an exclusive licensing agreement with Ramot at Tel Aviv University Ltd., Tel Aviv University's wholly owned technology transfer company.

The licensing agreement encompasses the development and commercialization of TAR-1, a single-chain antibody fragment in preclinical development that may have an advantage in treating cancer patients because of its high specificity and affinity to binding mutant p53 protein.

Under the terms of the agreement, Champions has obtained the worldwide rights to TAR-1 and is responsible for the further development of the compound. Champions will utilize its Biomerk Tumorgraft(TM) platform technology to evaluate the activity of TAR-1 and determine the best path forward for the compound in regards to indication, patient population and potential drug combinations. Ramot will receive an upfront payment and will be eligible to receive milestone payments and royalties if Champions chooses to continue the license terms, which will be determined based on results from testing TAR-1 in the predictive Tumorgraft platform.

Inhibits tumor growth

Prof. Beka Solomon from Tel Aviv University identified that TAR-1 binds to and restores the wild-type active conformation of mutant p53 protein with a high degree of specificity, leading to in vivo inhibition of tumor growth. Given the frequency of mutant p53 in cancer, TAR-1 has the potential to target a wide range of human cancers.

"Licensing TAR-1 demonstrates the progression of our strategy to build our own Tumorgraft-driven pipeline of oncology drugs, which we expect to yield improved clinical development success rates," said Guy Malchi, Champions Biotechnology's Head of Corporate Development and International Operations.

"We were impressed by the potential of TAR-1 and we are planning to continue to in-license oncology drug candidates with compelling science and to develop only those with positive Tumorgraft results." TAR-1 will undergo Tumorgraft testing as Champions completes Tumorgraft testing of its other oncology drug, SG410, a tubulin inhibitor.

"We are excited to work with Champions Biotechnology. Their predictive platform and experienced scientific and clinical team make them an ideal candidate to move TAR-1 forward into the clinic and on the path to commercialization," said Dr. Ze'ev Weinfeld, CEO, Ramot at Tel Aviv University Ltd.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Related medicine news :

1. Houston Dermatologists to Round Up for Sun Safety at World-Class LPGA Tour Championship
2. World Champion New York Yankees, BNY Mellon to be Honored as New York Blood Center Champions of Life
3. Planned Parenthood Advocacy Project Los Angeles County Celebrates Champions of Choice at Politics, Sex & Cocktails
4. Maldonado Medical LLC Champions Physician & Patient Rights for Better Reimbursement Schedules Nationwide
5. Illinois Dermatologists Tee Up for Sun Safety at Two World-Class Golf Championships
6. Mentors Who Support Students Receive TCWF Champions of Health Professions Diversity Award
7. The Byron Nelson: Championship Philosophy, Timeless Excellence
8. Champions Shawn Johnson & Phil Jackson Wear Energy Muse Jewelry
9. The Biggest Loser Champions Living Well
10. Insulet Applauds Employee for Bronze Medal Performance in World Blind Sailing Championships
11. The National Multiple Sclerosis Societys 35th Annual Dinner of Champions to Honor Summit Entertainments Rob Friedman
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Champions Biotechnology signs exclusive agreement with Tel Aviv University for cancer drug
(Date:3/23/2017)... ... March 23, 2017 , ... ... serving the families and businesses of the Norwalk and Vermillion areas, celebrates ... Recovery Center (N.O.R.A.) is a nonprofit, community-based substance abuse prevention and peer ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... owned and organized by HMP Communications Holdings, LLC, today announced that RestorixHealth® ... its nationwide network of wound centers interested in becoming Certified Wound Specialist Physicians ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... and workflow solutions, today named The Resource Group as their 2016 Microsoft Dynamics ... partner conference in Newport Beach, CA. The award recognizes The Resource Group ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... ... supplements that help improve all aspects of people’s health and nutrition, announced its ... nutritional products. , Natural Subsistence develops nutritional supplements that help people improve ...
(Date:3/23/2017)... ... March 23, 2017 , ... The Leaders ... life-altering and fatal diseases in opposition to the President’s Fiscal Year 2018 ... care, services, and hope for the most vulnerable among us. , The proposed ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)...  The U.S. Food and Drug Administration today granted ... adults and pediatric patients 12 years and older with ... not received prior chemotherapy. This is the first FDA-approved ... skin cancer. "While skin cancer is one ... form called Merkel cell cancer have not had an ...
(Date:3/23/2017)... and VANCOUVER, British Columbia , ... SPHS ) (the "Company" or "Sophiris"), a clinical ... of urological diseases, today announced that data from its ... drug as a focal treatment for localized prostate cancer, ... 2017 at the 32 nd Annual European Association ...
(Date:3/23/2017)... -- Research and Markets has announced the addition of ... their offering. ... The global oxygen therapy devices market to grow at a CAGR ... Global Oxygen Therapy Devices Market 2017-2021, has been prepared based on ... covers the market landscape and its growth prospects over the coming ...
Breaking Medicine Technology: