Navigation Links
Cethromycin achieves all endpoints in second pivotal Phase III Trial for treatment for pneumonia
Date:11/15/2007

.05, there is not a statistically significant difference between cethromycin and Biaxin, which supports non-inferiority.

  • Modified intent-to-treat clinical cure rate (mITT)- cethromycin 83.1% (217 subjects/261 subjects) compared to Biaxin 81.1% (206 subjects/254 subjects) [-4.8, +8.9] (p=0.5667). mITT is defined as subjects who received at least one dose of study medication and had a clinical diagnosis consistent with bacterial CAP confirmed by a positive pre-treatment chest X-ray and appropriate signs/symptoms. Based on the 83.1% clinical cure rate for cethromycin being between 80% and 90%, a delta value of 15% or less on the lower bound and greater than zero on the upper bound [-4.8, +8.9] establishes non-inferiority. Under this analysis, the study met the clinical cure rate endpoint in the mITT population. Since p>0.05, there is not a statistically significant difference between cethromycin and Biaxin, which supports non-inferiority.

  • Per protocol radiographic success rate- cethromycin 92.7% (202 subjects/218 subjects) compared to Biaxin 92.3% (192 subjects/208 subjects) [-4.9, +5.6] (p>0.9999). Based on the 92.7% radiographic success rate for cethromycin being greater than 90%, a delta value of 10% or less on the lower bound and greater than zero on the upper bound [-4.9, +5.6] establishes non-inferiority. Under this analysis, the study met the radiographic success rate endpoint in the PPc population. Since p>0.05, there is not a statistically significant difference between cethromycin and Biaxin, which supports non-inferiority.

  • Modified intent-to-treat radiographic success rate- cethromycin 82.4% (215 subjects/261 subjects) compared to Biaxin 81.5% (207 subjects/254 subjects) [-6.0, +7.7] (p=0.8195). Based on the 82.4% radiographic success rate for cethromycin being between 80% and 90%, a delta value of 15% or less on the lower bound and greater than zero on the upper bound [-6.0, +7.7]
    '/>"/>

Contact: Melanie Nimrodi
mnimrodi@mww.com
312-546-3508
MWW Group
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Kingfisher Healthcare (KFH) Achieves World Class Quality Platform
2. Kaiser Permanente Achieves Climate Action Leader Status
3. OSF HealthCare Achieves Impressive Tobacco Quit Rates with the Free & Clear(R) Quit For Life(TM) Program
4. LMS integrated obstetrics solution achieves general availability
5. ENDEAVOR IV achieves primary endpoint, demonstrates similar safety profile compared to Taxus stent
6. Pharsight Achieves $7.3 Million in Quarterly Revenue
7. Halogen Software Achieves Most Successful Quarter in Company History - Includes Record Year-Over-Year Overall and License Revenue
8. Burgeoning Population of Hepatitis C Virus Patients in Need of Second- and Third-Line Treatment Options
9. Medical Services International Maintains Pace in Second Quarter
10. CEOs Need an Advertising Check Up or Second Opinion
11. Trojan(R) Ranks U.S. Colleges and Universities in Second Annual Sexual Health Report Card
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... TX (PRWEB) April 21, 2015 The ... announced today it is opening its first freestanding emergency ... in Chandler, Arizona and will be licensed under Dignity ... the Dignity Health and Adeptus Health joint venture. , ... Regional and Mercy Gilbert Medical Centers said the new ...
(Date:4/21/2015)... Wireless Analytics, LLC , a pioneering provider ... Boston Business Journal as the 25th fastest-growing private company ... recent event celebrating the 2015 Pacesetters, the Boston ... in Massachusetts. , Wireless Analytics was ranked among 70 ... fastest revenue growth from 2011 through 2014. This ...
(Date:4/21/2015)... (PRWEB) April 21, 2015 ... 2015” provides comparative analysis on the therapeutic ... R&D pipelines by identifying new targets and ... Complete report with TOC is available @ ... also reviews key players involved in the ...
(Date:4/21/2015)... Edward Avalos, USDA Under Secretary for Marketing ... of the California Department of Food and Agriculture, have ... GrowRIVERSIDE Conference: The Future of Local Food, conference organizers ... nationally known experts intensifies an already strong line-up of ... slated to speak at the June 11-13 event. ...
(Date:4/21/2015)... IL (PRWEB) April 21, 2015 ... online retailer known for innovation at its healthiest, will ... starting May 1st. , At Wojo Nutrition, they’ve launched ... seekers with convenient solutions tailored to meet their multifaceted ... to be blended with any beverage, has been specially ...
Breaking Medicine News(10 mins):Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 2Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 3Health News:Wireless Analytics Ranked as 25th Fastest Growing Private Company in Massachusetts 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 4Health News:USDA Under Secretary, former CA Agriculture Director to Address 2nd Annual “GrowRIVERSIDE” Conference in June 2Health News:USDA Under Secretary, former CA Agriculture Director to Address 2nd Annual “GrowRIVERSIDE” Conference in June 3Health News:Wojo Nutrition Announces their Lines of Single Serving Liquid Vitamins will be Available for Purchase online at Abesmarket.com Beginning in May 2
... appear to be more predictive of three year prostate ... with a family history of prostate cancer, according to ... a journal of the American Association for Cancer Research. ... were just naturally higher in African-American men, suggesting a ...
... vital to certain types of memory, size matters. Numerous studies ... found that elderly adults who are more physically fit tend ... who are less fit. , The study, in the journal ... adults accounts for about 40 percent of their advantage in ...
... program for promoting healthy lifestyleATLANTA, Feb. 24 ... Youth for a Healthy Future Champion Award from ... Something Better (ING RFSB) program. The Healthy Youth ... and showcasing those communities throughout the nation that ...
... calcium among most popular supplements, according to survey - WASHINGTON, ... Aside from the usual staples of cereal, coffee filters, ... of American adults who take vitamins and other supplements every ... to the 2008 CRN Consumer Survey on Dietary Supplements ...
... and states reconsider funding for abstinence-only programs, the largest ... classes reveals that abstinence programs are plagued with factual ... and actively discourage the use of condoms to protect ... Texas Freedom Network Education Fund - Just Say ...
... technique to detect pancreatic cancer, researchers found they could ... benign, pre-cancerous, or even early stage indicators called mucinous ... for, yet deadly if ignored. The pancreas is extremely ... symptoms, the cancer is usually detected too late. , ...
Cached Medicine News:Health News:Physical fitness improves spatial memory, increases size of brain structure 2Health News:ING Run For Something Better Receives Healthy Youth for a Healthy Future Champion Award 2Health News:ING Run For Something Better Receives Healthy Youth for a Healthy Future Champion Award 3Health News:ING Run For Something Better Receives Healthy Youth for a Healthy Future Champion Award 4Health News:Consumers and Healthcare Professionals Agree - Kitchen Cabinet is Home for My Supplements 2Health News:Consumers and Healthcare Professionals Agree - Kitchen Cabinet is Home for My Supplements 3Health News:New Texas Study Reveals Serious Flaws in Abstinence Programs 2Health News:Determining risk for pancreatic cancer 2
(Date:4/21/2015)... , April 21, 2015 A groundbreaking new, ... known as the Acessa™ procedure is now readily available ... women aged 25-55 who suffer from this ... FACOG, the inventor and world,s leading practitioner of this ... myomectomy, has helped establish two new Los ...
(Date:4/21/2015)... Oxfordshire ... than doubled its overseas sales in just 4 years. ... the Queen,s Award for Enterprise, for Outstanding Achievement in ... HealthScience Communications consultancy, helping its clients bring new medicines ... more than doubled its exports in just 4 years, ...
(Date:4/21/2015)... Cardiologists at Henry Ford Hospital have implanted a ... an irregular heartbeat. With only handful of hospitals ... is able to add another option to its arsenal of ... heart,s ability to pump. "This is a ... Watchman implant at a non-clinical trial site," says cardiologist ...
Breaking Medicine Technology:New Minimally Invasive Treatment for Uterine Fibroids Offers Life-Changing Relief, Without a Hysterectomy, to 1 Million Southern California Women 2New Minimally Invasive Treatment for Uterine Fibroids Offers Life-Changing Relief, Without a Hysterectomy, to 1 Million Southern California Women 3New Minimally Invasive Treatment for Uterine Fibroids Offers Life-Changing Relief, Without a Hysterectomy, to 1 Million Southern California Women 4Queen's Award Crowns Achievements of Local Consultancy 2Queen's Award Crowns Achievements of Local Consultancy 3Queen's Award Crowns Achievements of Local Consultancy 4Queen's Award Crowns Achievements of Local Consultancy 5Stroke Risk Caused by Abnormal Heart Rhythm Reduced Without Blood Thinners 2Stroke Risk Caused by Abnormal Heart Rhythm Reduced Without Blood Thinners 3
... BOTHELL, Wash., April 6, 2011 BioLife Solutions, Inc. ... grade biopreservation media products for cells and tissues, today ... ended March 31, 2011. This represents 6% sequential growth ... growth from the first quarter of 2010.   ...
... Detroit Medical Center (DMC) Cardiovascular Institute (CVI) announced today ... heart-care by implanting the newly available "Protecta" defibrillator in ... took place at the DMC March 30, marked the ... implanted in a cardiac patient anywhere in the Midwest. ...
Cached Medicine Technology:BioLife Solutions Announces Record Quarterly Revenue 2BioLife Solutions Announces Record Quarterly Revenue 3BioLife Solutions Announces Record Quarterly Revenue 4DMC Cardiovascular Institute First in Midwest to Implant New "Protecta" Defibrillator in a Cardiac Patient 2DMC Cardiovascular Institute First in Midwest to Implant New "Protecta" Defibrillator in a Cardiac Patient 3
... SmartPLUG from Medennium is an innovative ... or tear duct, and conserve the ... to fit a range of punctum ... acrylic material, SmartPLUG adjusts to the ...
Provides quick freezing and quick defrosting. Lightweight probe tips have high conductivity silver. Useful for Cataract, Retinal Detachment, Glaucoma and Intra-vitreal surgery. Includes either one ca...
Khosla Precision and Quality in Medical and Surgical Products....
Khosla Precision and Quality in Medical and Surgical Products....
Medicine Products: