Navigation Links
Certain symptom clusters experienced after surgery for esophageal cancer predict poor prognosis
Date:11/24/2013

A new study has found that several months after surgery for esophageal cancer, different symptoms cluster together in different types of patients. In addition, patients with certain symptom clusters have an increased risk of dying from their disease. The findings are published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

Esophageal cancer is an aggressive cancer with a very poor prognosis, and surgery to remove the esophagus offers the only chance of a cure. Only about a quarter of patients who are diagnosed receive surgeryin the rest, the tumor is too advanced to remove or the patient is not fit for such extensive surgery. In patients who do undergo surgery, only 30 percent are alive five years after the surgery. The surgery is very extensive, and patients experience severe post-operative symptoms and limitations that affect their quality of life and daily living. Common symptoms include eating and swallowing problems, reflux, pain, and fatigue.

Research of symptoms in other cancers suggests that symptoms experienced by patients may present in specific groupings or clusters, and that these clusters may have an important impact on patient outcomes. In the current study of 402 patients who underwent surgery for esophageal cancer, Anna Wikman, PhD, of the Karolinska Institutet in Stockholm, Sweden, and her colleagues found that symptoms reported by patients six months after surgery clustered together in three groups: one symptom cluster included symptoms related to fatigue and pain, another cluster included symptoms related to reflux and cough, and a third cluster included symptoms related to eating difficulties. The patients who experienced the reflux/cough symptom cluster and the eating difficulties cluster were more likely to die within five years than patients who did not experience these symptom clusters.

"As this is the first study of symptom clusters in surgically treated esophageal cancer patients, further work is needed to confirm the existence of these symptom clusters in this patient population; however, the present findings do suggest that post-operative symptoms should not be considered in isolation but that clusters of symptoms must be considered," said Dr. Wikman. "It seems that patients who experience clustering of certain symptoms also have an increased mortality risk over and above the effect of other known prognostic factors. These findings suggest that it may be important to address these symptom clusters in the clinical setting in order to potentially reduce the increased mortality risk associated with them."


'/>"/>

Contact: Amy Molnar
sciencenewsroom@wiley.com
201-748-8844
Wiley
Source:Eurekalert

Related medicine news :

1. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
2. Certain Birth Control Pills May Carry Higher Blood Clot Risk: FDA
3. Codeine After Surgery Could Endanger Certain Kids: Study
4. Decision guide reduced uncertainty over breast cancer prevention, study finds
5. Certain Genetic Regions May Be Tied to Osteoporosis
6. Hot Flashes More Likely for Certain Smokers, Study Says
7. Early Study Hints at Link Between Certain Sunscreens, Endometriosis
8. Cabazitaxel can offer an advantage in certain patients
9. Antioxidant shows promise as treatment for certain features of autism, Stanford study finds
10. Gout Flare-ups Rise Sharply With Certain Foods: Study
11. Mouse Study Suggests Certain Fats Could Trigger Crohns, Colitis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2016)... ... ... ProBrand Reveal Volume 2 is a set of versatile and smooth logo reveals built exclusively ... can easily create a unique logo reveal in just a matter of minutes. Custom settings ... title presets to add a uniquely animated logo to any photos or videos. , ProBrand ...
(Date:4/30/2016)... ... April 30, 2016 , ... Create an abstract shape ... distort and manipulate three-dimensional shapes with ease all within Apple Motion . ... polygons, polygon texture animation, opacity texture animation, overall shape texture displacement, twist, camera ...
(Date:4/30/2016)... ... April 30, 2016 , ... Dr. Trevor Gardner, ... EMED, today signed a multifaceted agreement which will allow for the research and ... Department of Natural and Applied Sciences, Allied Health and Nursing will work together ...
(Date:4/29/2016)... ... April 30, 2016 , ... ... products, announces the Pick Up Springboard, an automotive invention that improves the storage ... industry is worth $162 billion," says Scott Cooper, CEO and Creative Director of ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... the Accreditation Council for Graduate Medical Education (ACGME) that it has received accreditation ... the first accreditation of three residency programs that Memorial is currently pursuing, including ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... , April 29, 2016  In the next ... to shift from systems dependent on CRTs monitors to ... of modality CRT Medical monitors and will automatically ... a host of foreseeable benefits to this technological ... existing modalities have to be replaced in order ...
(Date:4/29/2016)... 29, 2016 ReportsnReports.com adds ... market research report that provides an overview of ... at various stages, therapeutics assessment by drug target, ... and molecule type, along with latest updates, and ... key players involved in the therapeutic development for ...
(Date:4/29/2016)... ISELIN, New Jersey , April 29, 2016 ... Omnichannel Software Suite for Life Sciences, Product Development ... and Global Life Science Customer Base . ... healthcare solutions provider, today announced the acquisition of ... is a global leader in adaptive sales enablement ...
Breaking Medicine Technology: