Navigation Links
Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
Date:2/9/2010

An analysis of genetic and clinical data for nearly 800 patients with non-small cell lung cancer has identified differences in genetic characteristics that are associated with age and sex specific patterns of increased or decreased recurrence-free survival, according to a study in the February 10 issue of JAMA.

The five-year overall survival rate for lung cancer is only 15 percent, and it remains the leading cause of cancer-related death in the United States. An estimated 159,000 lung cancer deaths occurred in 2009, and more than 219,000 new cases were diagnosed. Almost half of these new cases are diagnosed in women, with approximately 30 percent to 40 percent of cases diagnosed in patients older than 70 years, with the majority of these cases (greater than 85 percent) nonsmall cell lung cancer (NSCLC), according to background information in the article.

"Despite evidence that clinical and pathologic factors (e.g., age, histology, smoking status, sex) are clinically relevant, little is known regarding the underlying biological differences in lung tumor gene expression among patients with different clinicopathologic characteristics. A deeper understanding of molecular abnormalities at a pathway level [involving gene expression and biochemical reactions that transmit information within and between cells] may help dissect the complex mechanisms of lung cancer oncogenesis [development of tumors], shed light on the biological underpinnings contributing to survival differences in NSCLC that are age- and sex-based, and further help identify specific cohorts of patients that may be more susceptible to novel individualized therapeutic strategies," the authors write.

William Mostertz, M.S., of Duke University, Durham, N.C., and colleagues examined clinically relevant differences in the underlying biology of NSCLC based on patient age and sex. The study consisted of an analysis, performed from July 2008 to June 2009, of 787 patients with
'/>"/>

Contact: Michelle Gailiun
michelle.gailiun@duke.edu
919-660-1306
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Hypertension may predict dementia in older adults with certain cognitive deficits
2. G Marks the Spot: Good Vibrations Proclaims February as National G-Spot Month -- Sex Toy Company Says "It Most Certainly Does Exist!"
3. Mount Sinai finds prenatal exposure to certain chemicals affects childhood neurodevelopment
4. Video Games Could Boost Certain Thinking Skills
5. Swine Flu Wanes, But Future Uncertain
6. Certain Childhood Cancers More Likely to Recur
7. Greater certainty in monitoring 3 therapeutic medications is facilitated by new CRMs
8. Certain Reflux Drugs Tied to Higher Post-Angioplasty Death Rate
9. FDA Authorizes Emergency Use of Intravenous Antiviral Peramivir for 2009 H1N1 Influenza for Certain Patients, Settings
10. Increased success a virtual certainty for rugby players
11. Minimally invasive radical prostatectomy shows advantages, but also certain complications
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... Florida (PRWEB) October 30, 2014 Timothy, ... visit to Pompano Beach firefighters, showing that you are ... , Timothy met firefighters Tracey and Carl at ... Galuppi’s Restaurant and the Pompano Beach Chamber of Commerce. ... the fire truck, letting Timothy wear his real fireman’s ...
(Date:10/30/2014)... High efficacy and low irritation ... medical-grade skin care domain: Cosmederm, the specialty biotechnology ... topical dermatological products, today announces the launch of ... patented COSMEDERM®-7 anti-irritant technology. , Formulated with ... 70%) and a low pH (pH 1.2 and ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Paramount Rx, ... care, is increasing efforts to help people save money ... continue to increase for prescription drugs in the new ... savings and resources to bridge the relationship between consumers, ... of the biggest challenges people face today with medical ...
(Date:10/30/2014)... HealthDay Reporter , WEDNESDAY, ... genes have been identified that appear linked to autism ... say they are on their way to discovering up ... disorder. Autism spectrum disorders include a range of ... repetitive behaviors. An estimated one in 68 U.S. children ...
(Date:10/30/2014)... 2014 Dr. Joseph Furlin MD, a certified ... his practices; OB GYN in Melrose Park, IL ... website contains important information about each of the care services ... patient forms in English and Spanish. The navigation of ... on the website provide Dr. Furlin’s patients with important information ...
Breaking Medicine News(10 mins):Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 2Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 3Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 4Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 2Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 3Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 4Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 2Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 3Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 2Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2
... , , Cuts Will ... to Recent Cuts , , ... Chairman Max Baucus (D-Mont.) issued his recommendations for healthcare reform in ... bill contains several provisions that affect home medical equipment, ranging from ...
... remain unknown, expert says, , WEDNESDAY, Sept. 16 (HealthDay News) ... for older women: stopping hot flashes. , In a ... the New England Journal of Medicine , researchers from ... cetrorelix (Cetrotide) helped ease hot flash symptoms. , "It ...
... obesity, but beverage industry balks at proposal , WEDNESDAY, Sept. ... per ounce of soda and other sugary drinks could stem ... first year alone, health experts say. , That windfall could ... to prevent obesity, say a group of prominent researchers in ...
... , NEW YORK, Sept. 16 As ... If the thought of skinny jeans has you feeling uneasy, think ... you into those new jeans. , , Listen ... , , Registered journalists can access video, audio, ...
... , , MINNEAPOLIS, Sept. 16 ... Board Members and thanked outgoing members for their service to the ... was elected as the new Board Chair. The full roster of ... David Fisher, Board Chair - ...
... , THE GLOBALIZATION PLATFORM ... More than 120 delegates, including heads of state, acclaimed artists, Nobel ... City for the fourth annual Global Creative Leadership Summit , ... globalization. Organized by the Louise Blouin Foundation , an international ...
Cached Medicine News:Health News:Senate Finance Committee Cuts Home Medical Equipment in Reform Package 2Health News:Fertility Drug Shows Potential Against Hot Flashes 2Health News:Fertility Drug Shows Potential Against Hot Flashes 3Health News:'Soda Tax' Wins Health Experts' Support 2Health News:'Soda Tax' Wins Health Experts' Support 3Health News:'Soda Tax' Wins Health Experts' Support 4Health News:ClearWay Minnesota(SM) Board Approves New Officers 2Health News:Global Creative Leadership Summit 23-25 September 2009 2Health News:Global Creative Leadership Summit 23-25 September 2009 3
(Date:10/30/2014)... YORK , Oct. 30, 2014  The number ... States is growing steadily, thanks to drug ... as a result of the economic downturn, retail clinic ... a year of opportunities, as the number of retail ... researcher,s report, Retail Clinics Market Overview and 2014 ...
(Date:10/30/2014)... Molecular Profiles Ltd., a subsidiary of Columbia ... Maryland -based Xceleron have announced a collaboration ... development that will be launched at AAPS in ... This partnership extends Molecular Profiles, new ROADMAP to Clinical ... month. The company also has complementary collaborations in place ...
(Date:10/30/2014)... LOS ANGELES , Oct. 30, 2014 /PRNewswire/ ... biopharmaceutical research and development company specializing in oncology, ... technology and its lead drug candidate, aldoxorubicin.  The ... A New Approach," will be given by ... the Sarcoma Oncology Center and principal investigator of ...
Breaking Medicine Technology:Report: Drugstore Chains Drive Retail Clinic Growth 2Report: Drugstore Chains Drive Retail Clinic Growth 3Molecular Profiles To Launch US Strategic Alliance At AAPS 2Molecular Profiles To Launch US Strategic Alliance At AAPS 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 2CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 4
... AVANIR Pharmaceuticals, Inc. (Nasdaq: AVNR ) ... for the quarter ended December 31, 2010 before market ... and Chief Executive Officer, Randall Kaye, M.D., Senior Vice ... President, Finance, will host an investment community conference call ...
... 27, 2011 Higher volume drove four ... in Q4 led to growth in operating income. ... (non-GAAP). Full-year 2010 revenue topped $23 billion as ... exceed $1 billion in annual sales. Full-year 2010 ...
Cached Medicine Technology:Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 2Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 3Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 4Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 5Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 6Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 7Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 8Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 9Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 10Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 11Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 12Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 13Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 14Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 15Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 16Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 17Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 18Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 19Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 20Lilly Reports Fourth-Quarter and Full-Year 2010 Results, Provides 2011 Financial Guidance 21
For accurately monitoring core temperature and heart and breath sounds....
For accurately monitoring core temperature and heart and breath sounds....
... The bodys warmth beneath drapes. The life-giving ... are yours to guard, measure, stabilize and ... products helps you do your job, giving ... most comfortable and precise management of your ...
... Level 1 enables hospitals ... patient monitors to a ... Our temperature monitoring disposale ... are superior in their ...
Medicine Products: