Navigation Links
Certain Genes Could Add to Alcoholism Risk
Date:4/13/2011

WEDNESDAY, April 13 (HealthDay News) -- People with certain variations in a gene called GABRA2 have an increased risk for alcoholism, a new study has found.

When under stress, people with these gene variations tend to act impulsively, which can lead to the development of drinking problems, explained the study's lead author, Sandra Villafuerte, a research investigator at the Molecular and Behavioral Neuroscience Institute and the department of psychiatry at the University of Michigan.

She and her colleagues looked at 449 people from 173 families, including 129 families with at least one member who had been diagnosed with alcohol dependence or abuse.

The investigators also used functional MRI scans to observe changes in blood flow in the brains of 44 young adults from these families as they anticipated winning or losing money. This enabled the researchers to see how variations in GABRA2 affect the brain's response in various situations.

The brain scans revealed that people with one form of the GABRA2 associated with alcoholism had greatly increased levels of activation in an area of the brain called the insula when they were anticipating rewards or losses. Previous research had found an association between the insula and addictive behavior.

"We believe these results suggest GABRA2 exerts an influence on an underlying neural system that impacts early risk factors and, later, alcohol dependency," Margit Burmeister, a research professor at the institute, a professor of psychiatry and human genetics at the university's medical school and the study's senior author, said in a university news release. "In the future, we hope to further examine the effects of family environment and other behavioral and environmental factors."

Genetic risk factors don't act alone and having them does not automatically mean that someone will become an alcoholic, the researchers emphasized.

The study was published online April 12 in Molecular Psychiatry.

More information

The U.S. National Institute on Alcohol Abuse and Alcoholism has more about alcoholism.

-- Robert Preidt

SOURCE: University of Michigan, news release, April 12, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Prenatal exposure to certain pollutants linked to behavioral problems in young children
2. Parkinsons May Have Links to Certain Cancers, Study Suggests
3. Certain Diabetes Drugs Better for Heart Health, Study Finds
4. Progesterone Treatment Cuts Preterm Birth Risk in Certain Women
5. Certain breast cancer patients worry excessively about recurrence
6. Study Questions Rise in Use of Certain Cholesterol Drugs
7. Treatment for alcohol dependence might work best in certain populations, research suggests
8. Aspirin May Protect Against Colorectal Cancer -- But Only in Certain People
9. Limited lymph node removal for certain breast cancer does not appear to result in poorer survival
10. For-Profit Hospices May Prefer Certain Types of Patients: Study
11. Adult ADHD Often Precedes Certain Type of Dementia: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Certain Genes Could Add to Alcoholism Risk
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history of ... Brink” is the creation of published author, William Nowers. Captain Nowers and his ... veteran, he spent thirty years in the Navy. Following his career as a ...
(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
(Date:10/12/2017)... , ... October 12, 2017 , ... The American College ... to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in ... , In honor of Morris F. Collen, a pioneer in the field of medical ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... 12, 2017   EcoVadis , the leading platform for environmental, social ... annual edition of its Global CSR Risk and Performance Index. The report ... based on Scorecard Ratings that analyzed nearly 800,000 data points across the ... ... ...
(Date:9/12/2017)... 12, 2017  ValGenesis Inc., the global leader ... pleased to announce the appointment of Dr. ... Board of Directors and Chairman of Advisory Board ... science companies to manage their entire validation lifecycle ... in this process. Furthermore, ValGenesis VLMS enables rigorous ...
(Date:9/9/2017)... 8, 2017 Dealmed Medical Supplies, ... medical equipment, supplies, drugs, vaccines, and specialty medical products ... an agreement to acquire Vantage Medical Supplies, a major ... Holtsville, New York . ... and emerging medical practices, will operate under the Dealmed ...
Breaking Medicine Technology: