Navigation Links
Certain Cancer Drugs May Have Fatal Side Effects: Analysis
Date:2/6/2012

MONDAY, Feb. 6 (HealthDay News) -- Treatment with three relatively new cancer drugs may be linked to a slightly increased risk of death, a new analysis suggests.

While the risk is low, it should be taken into account by doctors and patients, according to Dana-Farber Cancer Institute scientists and colleagues.

The investigators analyzed the findings of 10 clinical trials that included nearly 4,700 patients treated with sorafenib (Nexavar) for kidney and liver cancer; sunitinib (Sutent) for kidney cancer and gastrointestinal stromal tumor; or pazopanib (Votrient) for kidney cancer.

These so-called "targeted" drugs are used to stop the growth or spread of cancer by blocking the vascular endothelial growth factor tyrosine kinase receptors in cancer cells, the researchers explained in a Dana-Farber news release.

The analysis of the clinical trials revealed that the incidence of fatal complications was 1.5 percent in patients who received any of the three drugs, compared with 0.7 percent in patients who received standard treatments or placebos.

Bleeding, heart attack and heart failure were the most common fatal side effects noted in the clinical trials. In addition, liver failure was also reported, according to the report published in the Feb. 6 edition of the Journal of Clinical Oncology.

"There is no doubt for the average patient, these drugs have benefits and are [U.S. Food and Drug Administration]-approved for these indications," study leader Dr. Toni Choueiri said in the news release. "While the absolute incidence of these fatal side effects is very small, the relative risks are higher and patients and practitioners need to be aware of it."

More information

The U.S. National Cancer Institute has more about targeted cancer therapies.

-- Robert Preidt
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
2. Certain pain medications do not appear to be associated with skin cancer risk
3. AGA offers new recommendations for CRC surveillance for certain patients with IBD
4. Smoking significantly increases risk of aneurysm in people with certain genes
5. American Stroke Association Late-Breaking Science Report: Surgery, Stenting to Open Blocked Neck Arteries Similar in Safety, Efficacy, But Show Differences in Stroke, Heart Attack and Death Rates at Certain Ages
6. Certain Bone Drugs May Lower Breast Cancer Risk
7. Football Injuries More Likely on Certain Artificial Turf
8. Plavix Can Help Cut Death Risk in Certain Heart Patients
9. The Worst Is Over, but the Road to Growth Is Uncertain - The 17th Annual CFO Rising Conference & Exhibition
10. Perhaps a longer lifespan, certainly a longer health span
11. One in Five Parents Would Spank in Certain Settings
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Certain Cancer Drugs May Have Fatal Side Effects: Analysis
(Date:7/23/2014)... Agricultural and Forestry University in Shaanxi province, and the ... agreement that lays the groundwork for establishing the Sino-U.S. ... The signing ceremony was held in the city of ... the U.S. Department of Agriculture and China,s Ministry of ... event for UC Davis and for our World Food ...
(Date:7/23/2014)... FL (PRWEB) July 23, 2014 Rich Dad® ... the success of their charity yard sale to support Habit ... raised and 100% of the proceeds will be donated to ... the event are being donated to the Habitat for Humanity ... Myers, Florida 33903. , One of the highlights of ...
(Date:7/23/2014)... CA (PRWEB) July 23, 2014 Global ... delivering Enhanced External Counterpulsation (EECP), is celebrating ... receives EECP therapy at the health center. , ... heart disease. Since receiving ongoing EECP therapy since 1999, ... When Sara Soulati, CEO of Global Cardio Care, introduced ...
(Date:7/23/2014)... FL (PRWEB) July 23, 2014 Bodybuilding.com, ... largest online retailer of nutritional supplements, has officially opened ... BPI SPORTS , the fastest growing sports nutrition ... categories: , Brand of the Year, Best Tasting Protein ... Year, Protein Powder of the year - Whey-HD™, Pre-workout ...
(Date:7/23/2014)... secrets to better treating the pernicious disorders of obesity ... paper from American University,s Center for Behavioral Neuroscience. In ... with therapies aimed at areas of the brain responsible ... the hippocampus could play a role in reducing certain ... and preventive measures often fall short. This is a ...
Breaking Medicine News(10 mins):Health News:Global food safety research agreement signed by China and UC Davis 2Health News:Global food safety research agreement signed by China and UC Davis 3Health News:Rich Dad Education Charity Yard Sale Raises Over $650 for Habitat for Humanity of Lee and Hendry Counties 2Health News:Global Cardio Care Celebrates EECP Patient’s 100th Birthday 2Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 2Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 3Health News:Targeting the brain to treat obesity 2Health News:Targeting the brain to treat obesity 3
... This month, Pakistan is introducing a new combination vaccine ... influenzae type b (Hib) and four other common childhood ... deadly meningitis and pneumonia, is one of the top ... with treatment, an estimated 23,000 children die of Hib ...
... Calif., Oct. 31 David J. Pecker,Chairman and ... Chris,Lockwood, Mike Carlson, and Allan Donnelly have joined ... Muscle & Fitness Hers magazines, reporting to,Laya Clark ... of AMI,s Enthusiast Group. The Group includes these ...
... blood transfusions,3-year recovery, NEW YORK, Oct. 31 ... Matthew Long, a blood transfusion,recipient, to the New York ... City firefighter, former triathlete and competitive marathoner, was,critically injured ... bus while,biking to work on December 23, 2005. He ...
... Pregnant women whose labor stalls while in the active phase ... infants by waiting out the delivery process for an extra ... the University of California, San Francisco. , By doing ... the more dangerous and expensive surgical approach per year ...
... calorie burn , , FRIDAY, Oct. 31 (HealthDay News) -- ... stimulant produced by the human body has been discovered. ... antibody catalyst, GHR-11E11, increased the metabolic rate in fasting ... went 24 hours without food. , The antibody counteracts ...
... in this group , , FRIDAY, Oct. 31 (HealthDay News) ... death among kidney failure patients, and inflammation and malnutrition ... these people, Johns Hopkins researchers report. , The researchers ... on dialysis. Over 9.5 years, there were 658 deaths, ...
Cached Medicine News:Health News:Pakistan introduces vaccine to prevent top child killer 2Health News:American Media Inc. Names Chris Lockwood, Mike Carlson, and Allan Donnelly to Lead Editorial Teams at Enthusiast Group of Fitness Titles 2Health News:Blood Recipient Matthew Long Returns to New York Marathon 2Health News:Patience during stalled labor can avoid many C-sections, UCSF study shows 2Health News:Scientists Develop New Strategy to Fight Obesity 2Health News:Kidney Patients More Susceptible to Sudden Cardiac Death 2
(Date:7/23/2014)... July 23, 2014 The Board of Directors ... leading provider of clinical trial imaging solutions, announced today ... named president and chief executive officer, effective immediately.  Mr. ... 2013 and has held the positions of interim president ... Dr. Charles E. Phelps , Ph.D., chairman ...
(Date:7/23/2014)... , July 23, 2014 Pharmavite LLC ... company,s chief customer officer effective immediately. Toll recently served ... sales and marketing, category management, private label and sales ... In his new global role, Toll will expand his ... sales planning. "Toll,s appointment to chief customer ...
(Date:7/23/2014)... , July 23, 2014  RT Oncology Services Corporation ... to join its board of directors. Mr. Mundie is ... where he works on strategic projects within the company ... Microsoft,s chief research and strategy officer. ... of RainTree, said, "Craig is a visionary technology executive. ...
Breaking Medicine Technology:Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 2Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 3Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 4Craig Mundie Joins RainTree Oncology Board of Directors 2Craig Mundie Joins RainTree Oncology Board of Directors 3
Fome-Cuf® tubes can breathe with the patient to provide a safe, effective, and low pressure seal throughout the ventilatory cycle....
Portex® pediatric tracheostomy tubes offer a choice in both form and fit. , ,The anatomical shape of the tube shaft along with the caudal angle of the 15 mm connector provide comfort and security...
Indications For Usage: ,Bypass upper airway obstructions, provide long term ventilation, support and/or manage tracheal/bronchial secretions....
KIMBERLY-CLARK BALLARD Neonatal and Pediatric TRACH CARE Manifold features lavage/irrigation port and locking thumb port. Multiple French sizes and packaging configurations. Gamma sterilized....
Medicine Products: