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Center for Human Reproduction Receives Two New Patent Approvals on Androgen Supplementation for Women with Diminished Ovarian Reserve (DOR) Attempting to Conceive
Date:8/14/2013

New York, NY (PRWEB) August 14, 2013

Center for Human Reproduction (CHR), a leading fertility research and treatment center in New York City, announced approval of two patent applications regarding the therapeutic benefits and mechanisms of androgen supplementation for pregnancy chances of women with diminished ovarian reserve (DOR).

Combined, the two newly awarded patents (#8,501,718 and #8,501,719) describe the use of supplementation with androgens, such as dehydroepiandrosterone (DHEA), to restore ovarian environments deteriorated due to advanced female age (over 38 years) or premature ovarian aging (indicated by abnormally high FSH or abnormally low AMH levels for age).

The new patents follow the two previously awarded patents (#7,615,544 and #8,067,400), which describe DHEA supplementation as a means to improve various quality parameters of eggs and embryos, to shorten time to pregnancy and to improve pregnancy rates. Improving pregnancy chances for women with DOR has been a long-standing research focus at CHR, and CHR’s introduction of DHEA supplementation, almost a decade ago, truly revolutionized fertility treatments for women with DOR.

Having now discovered the mechanisms by which supplementation with DHEA or other androgens achieves all of these effects, one of the new patents (#8,501,719) describes these improvements as stemming from restoration of the ovarian environment to its youthful state with healthy androgen levels. The other (#8,501,718) identifies improvements in anti-Müllerian hormone (AMH) levels after androgen supplementation as a positive prognostic sign in the context of female fertility.

“These two new patents reflect research f
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