Navigation Links
Cellular decision on the computer
Date:7/14/2008

and mathematician Professor Roland Eils have investigated what makes human skin cells migrate into a wound to make it heal. They showed that the cells take several steps to decide to "start moving", how fast to do so, where to go and when to stop again. For the process to start, various external signals have to be received in a particular order. The scientists subsequently simulated this process on the computer. In doing so, they succeeded in predicting the molecular targets by which a cell's behavior can be changed in a particular direction.

Metastasizing cancer cells, too, migrate through the body though in their case, it is undesired. They decide to migrate even when normal cells would not move. Using the new simulation method developed by the DKFZ researchers, it is possible to simulate how the genes involved in this process interact and, thus, find out the molecular targets and the order in which they need to be hit so that tumor cells stop migrating. Therefore, the method is relevant not only for basic medical research, but also forges new paths in cancer medicine.

H. Busch et al. Gene network dynamics controlling keratinocyte migration. DOI:10.1038/msb.2008.36 The task of the Deutsches Krebsforschungszentrum in Heidelberg (German Cancer Research Center, DKFZ) is to systematically investigate the mechanisms of cancer development and to identify cancer risk factors. The results of this basic research are expected to lead to new approaches in the prevention, diagnosis and treatment of cancer. The Center is financed to 90 percent by the Federal Ministry of Education and Research and to 10 percent by the State of Baden-Wuerttemberg. It is a member of the Helmholtz Association of National Research Centers (Helmholtz-Gemeinschaft Deutscher Forschungszentren e.V.).


'/>"/>
Contact: Dr. Stefanie Seltmann
s.seltmann@dkfz.de
49-622-142-2854
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Global Med Technologies(R) Announces U.S. Release of Proven Tissue and Cellular Therapy Product
2. Molecule Uses Cellular Recycling to Treat Kidney Cancer
3. Scripps Research scientists find seizure drug reverses cellular effects
4. ReCellular and American Red Cross Announce Cell-Phone Recycling Campaign
5. Secrets of cellular signaling shed light on new cancer stem cell therapies
6. Obesity chokes up the cellular power plant
7. NIAID scientists identify new cellular receptor for HIV
8. Engineering chimeric polypeptides to illuminate cellular redox states
9. Story ideas from Molecular and Cellular Proteomics
10. How does Fu-Zheng-Jie-Du-Decoction act on PTEN expression in hepatocellular carcinoma?
11. St. Jude finds link between cellular defense processes, showing how cancer cells survive
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... (PRWEB) August 27, 2014 For nearly ... performances by the beloved mantra singers Deva Premal & ... Following the release of their latest album in May, ... down in twenty-two countries around the globe, including Russia, ... Argentina and across Europe. With a new album and ...
(Date:8/27/2014)... BESLER Consulting , a leading provider ... is pleased to announce that it has been named ... Companies. The list represents the most comprehensive look at ... , "It's been an exciting year for our company ... year's Inc. 5000 list,” said Jonathan Besler, BESLER’s President ...
(Date:8/27/2014)... August 27, 2014 Home Care ... care for seniors, is proud to announce the next ... upcoming webinar will feature Dr. Suzanne Steinbaum, attending cardiologist ... Hospital in New York City, National Spokesperson for the ... webinar will cover the issues surrounding women and heart ...
(Date:8/27/2014)... clinical trial participation in the largest ongoing observational study ... not representative of the larger patient base, according to ... Jay Udell. The study authors call into question the ... and suggest the use of broader enrollment criteria and ... know that clinical trials can be tremendously expensive and ...
(Date:8/27/2014)... (Lebanon, NH 8/27/14)Dartmouth cancer researchers developed and tested ... and environmental interactions that contribute to disease as ... , The approach fills a gap in ... from complex interactions among genetic and environmental factors. ... relevant interactions versus those that reflect chance combinations ...
Breaking Medicine News(10 mins):Health News:Deva Premal & Miten's Mantras For Life Tour Announced 2Health News:Deva Premal & Miten's Mantras For Life Tour Announced 3Health News:BESLER Consulting Among America’s Fastest Growing Private Companies 2Health News:Home Care Assistance of Scottsdale to Host Webinar on Heart Health, Featuring Dr. Suzanne Steinbaum 2Health News:Home Care Assistance of Scottsdale to Host Webinar on Heart Health, Featuring Dr. Suzanne Steinbaum 3Health News:Participants of cardiac clinic trials do not represent real world patients, study finds 2Health News:Dartmouth isolates environmental influences in genome-wide association studies 2
... study, there is a connection between certain bacteria in ... of using probiotics to treat autism.// ... this study. Though the results are very preliminary, he ... propose any link between autism and childhood vaccinations. ...
... of medical tourism has created new vistas, enabling a ... world.// In the race for being the best in ... the industry’s powerful trident - Pharmaceutical Industry, Doctors and ... well as diseases”, said Karl Marx, and what better ...
... from Spain are not too comfortable with the outcome of ... grace//, could carry a risk of formation of fatal blood ... 2000 as an upgraded version of bare-metal stents. ... have the drug-lined versions of the stents, which are designed ...
... Attention Deficit Hyperactivity Disorder (ADHD) cannot sit calmly at ... health professionals and parents are familiar with the symptoms, ... topic. ,The FDA has given instructions that ... should put up warnings about the possible side effects ...
... James, the British chairman of the International Obesity Task ... the obesity epidemic in poor countries. ,"The ... which subsidize and distort the market to make fats ... James said at the 10th International Obesity Congress in ...
... 150th anniversary celebrations of Madras University, his alma mater ... institutions in India. ,Speaking on the occasion, ... "Good teaching emanates from research. Any university is judged ... academics here. ,He opened a virtual university ...
Cached Medicine News:Health News:Probiotics – a probable treatment for Autis 2Health News:Chemistry Over The Counter: Is It Just What The Doctor Ordered? 2Health News:Chemistry Over The Counter: Is It Just What The Doctor Ordered? 3Health News:Chemistry Over The Counter: Is It Just What The Doctor Ordered? 4Health News:Alternative therapies for ADHD 2Health News:Alternative therapies for ADHD 3Health News:President Launches Madras University's 150th Year Celebrations 2
(Date:8/27/2014)... Calif. , Aug. 27, 2014 /PRNewswire-iReach/ -- ... response system design, blended emergency medical training and ... (automated external defibrillator) training from the Department ... Army Reserve 81 st Regional Support ... and Investigations contract includes nationwide CPR/AED/First Aid training. ...
(Date:8/27/2014)... Auxilium Pharmaceuticals , Inc. (NASDAQ: AUXL ), ... certain members of the executive management team will participate ... September 8-10, 2014 in New York ... President, is scheduled to present an overview of the ... on Wednesday, September 10, 2014. The presentation ...
(Date:8/27/2014)... NEW YORK and LONDON , Aug. ... market research solutions, MarketResearch.com is pleased to announce ... Information Medical Devices Knowledge Center. The ... hosting the latest market research in the healthcare ... of reports from industry expert, Kalorama Information, published ...
Breaking Medicine Technology:Emergency University Equips Homeland Security, Army Reserve with SCA Response Program to Save Lives of Sudden Cardiac Arrest Victims 2Emergency University Equips Homeland Security, Army Reserve with SCA Response Program to Save Lives of Sudden Cardiac Arrest Victims 3Auxilium Pharmaceuticals, Inc. To Present At The Morgan Stanley Healthcare Conference 2Auxilium Pharmaceuticals, Inc. To Present At The Morgan Stanley Healthcare Conference 3MarketResearch.com: New Medical Devices Research Reports Added to Kalorama Information Knowledge Center 2MarketResearch.com: New Medical Devices Research Reports Added to Kalorama Information Knowledge Center 3
Multi-Acuity: Letter Acuity, Tumbling E,and Allen Tests....
Child Acuity: Allen, Tumbling E, and Landolt C Tests....
Coat-A-Count PSA IRMA is an,immunoradiometric assay intended for the,quantitative measurement of,prostate-specific antigen (PSA) in serum,to aid in the management of prostate,cancer patient...
... This is a self-collected laboratory analysis that measures ... Prostate Specific Antigen (PSA). Annual PSA testing is ... of prostate disease such as prostate cancer. ... Lab, test analysis by BIOSAFE's CLIA Certified Laboratory, ...
Medicine Products: