Navigation Links
Cellular Disorder Might Influence Behavior
Date:12/8/2007

Mouse study hints at link between mitochondria, memory and socialization

FRIDAY, Dec. 7 (HealthDay News) -- In laboratory mice, respiration deficiencies in mitochondria (the source of energy in cells) are associated with changes in social behavior and spatial memory, Japanese researchers report.

The finding may help improve understanding about the link between mitochondrial malfunction and mental illness in humans, they said.

Previous research found that mitochondrial disorders may contribute to many kinds of health problems, including muscle weakness, stroke, diabetes, or heart disease. Major mitochondrial genetic defects have been identified in patients with neurodegenerative diseases such as Alzheimer's and Parkinson's.

For this study, the researchers used genetically-engineered mice with a defect that affected the last stage of mitochondrial energy processing called oxidative phosphorylation.

The researchers were surprised to find that the mice had more improved spatial memory -- they were better able to remember locations in a maze -- than normal mice. However, the genetically-altered mice scored poorly in tests of social behavior toward unfamiliar mice.

The findings were expected to be presented this week in Washington, D.C., at the annual meeting of the American Society for Cell Biology.

More information

The University of Texas Medical Branch has more about mitochondria.



-- Robert Preidt



SOURCE: American Society for Cell Biology, news release, Dec. 4, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Story ideas from molecular & cellular proteomics
2. A Chinese medicine compound has satisfactory anti-cancer effects on hepatocellular carcinoma
3. ReCellular Named Exclusive Cell Phone Recycling Partner for Consumer Cellular
4. Intra-arterial combination chemotherapy induces long-term survival for hepatocellular carcinoma
5. A new chemotherapeutic target for hepatocellular carcinoma
6. Helicobacter pylori inhibits intercellular communication of cultured gastric cells
7. UC Davis researchers identify a cellular pathway that makes prostate cancer fatal
8. Gene May Help Spur Obsessive-Compulsive Disorder
9. Bipolar disorder relapses halved by Melbourne researchers
10. New Database to Help Speed Search for Bipolar Disorder Genes
11. Study documents rapid increase in youth bipolar disorder diagnoses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... has recently contributed a medical article to the newly revamped Cosmetic Town ... article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the ... – Miles by Moonlight to raise money for the American Heart Association Heart Walk. ... , Teams will work together to keep their treadmills moving for 5 hours. Treadmills ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United States, single-family ... some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average ... extremely low property-tax rates, which contributes to the relatively lower cost of living ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... content management, presents its enhanced Pepper Flow promotional review platform at the ... Pepper Flow’s increased insight-driven capabilities help marketers streamline the medical, legal, and ...
Breaking Medicine News(10 mins):
(Date:9/23/2017)... -- Janssen Biotech, Inc. (Janssen) announced today that it ... Food and Drug Administration (FDA) for the Biologics License ... of moderately to severely active rheumatoid arthritis (RA). The ... to further evaluate the safety of sirukumab in the ... "We are disappointed by ...
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a ... targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , ...
(Date:9/18/2017)... R.I. , Sept. 18, 2017 /PRNewswire/ ... the fields of bioinformatics and immune engineering, ... a protective avian influenza A (H7N9) vaccine. ... distantly related to seasonal influenza and presents ... rely on prior exposure to be effective. ...
Breaking Medicine Technology: