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Cells on path to becoming mature T-cells more flexible than commonly thought
Date:4/9/2008

myeloid cells in the normal thymus. Its very hard to accommodate these data with our old way of thinking about T-cell development, notes Bhandoola.

Now, we want to understand how ETPs make the decision to become myeloid cells or T cells within the thymus, says Bell. Although our research is focused on basic science, it is relevant to figuring out how T-cell leukemias develop from early progenitor cells.

Were also wondering about the myeloid cells in the thymus that arise from ETPs, adds Bhandoola. Are they doing something we need to know about, and what could that be?


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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert

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