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Cell sugar concentrations affect hyaluronan production and cancer growth
Date:2/27/2013

can increase its activeness. This finding constituted part of the doctoral study of Lic. Med. Hanna Siiskonen, which was recently examined at the University of Eastern Finland.

By regulating hyaluronan levels, it may be possible to prevent the progression of cancer and other pathologies. The first clinical trials involving enzymes which break down hyaluronan have been able to slow down the growth and movement of cancer cells and to enhance the effectiveness of cancer drugs.

At the UEF Institute of Biomedicine, the research group of Professor Raija Tammi and Professor Markku Tammi has been studying hyaluronan for 25 years already, and the group's research is internationally renowned. The group focuses on cell biological mechanisms which regulate hyaluronan production. Together with its partners, the group has established a link between increased hyaluronan levels and a negative cancer prognosis in many cancer types, such as breast, prostate, colon, uterine, lung and ovarian cancer.


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Contact: Kirsi Rilla
kirsi.rilla@uef.fi
358-403-553-218
University of Eastern Finland
Source:Eurekalert  

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