Navigation Links
Cell mechanics may hold key to how cancer spreads and recurs
Date:8/7/2014

cells "woke up" and began to multiply and spread.

Wang speculates that these properties of dormancy and reawakening when the mechanical environment is more inviting may explain why soft tissues, such as the brain or lungs, are most vulnerable to metastasis.

"We have many different types of organs where solid tumors originate, but if you look at the metastasized sites, the majority are in soft tissues," said Wang. "Brain, lung, liver and bone marrow, all soft. So it may not be coincidence. We need to do more research."

Next, Wang and colleagues hope to tackle the question of what makes TRCs so resistant to drugs, a trait that makes recurrent cancer much harder to treat. Unlocking this puzzle may help doctors fight recurrent cancer, although Wang hopes that understanding how TRCs work can lead to treatments that prevent metastasis in the first place.

"The key issue in this paper is outlining the mechanisms that control how TRCs proliferate," Wang said. "The importance of knowing these mechanisms is that we now have targets that we didn't have before, specific targets for new types of drugs that will interfere with this renewal pathway. It could give us a new avenue for treatment and preventing relapse."


'/>"/>
Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Sharp Rise in Risk With New Breast Cancer Gene, Scientists Say
2. NuvOx Pharma Begins Clinical Trial to Treat Brain Cancer
3. Gut microbiome analysis improved noninvasive colorectal cancer screening
4. Young Cancer Patients at Loma Linda University Children's Hospital Treated to an Afternoon of Fun with UCLA Football Players, Sponsored by Stater Bros
5. Gene increases risk of breast cancer to 1 in 3 by age 70
6. Daily Aspirin May Help Prevent Cancer, Study Shows
7. Cancer Diagnostics Universe Discussed in Comprehensive VPG Research Study Published at MarketPublishers.com
8. One in 10 Cancer Survivors Still Smoke Years Later, Study Finds
9. Study shows low uptake of colorectal cancer screening by African Americans in a Veterans Affairs healthcare network
10. Allegheny Health Network Team Develops Biomarker for Early Detection of Esophageal Cancer
11. Study: Many cancer survivors smoke years after diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... 2014 DePuy Pinnacle hip lawsuits ... of the artificial hip system was defectively designed ... courts, Bernstein Liebhard LLP reports. According to an ... Court on December 2nd, counsel in 10 DePuy ... plaintiffs on November 19, 2014, with depositions to ...
(Date:12/20/2014)... The Doctor’s Office Urgent Care of Paramus, New Jersey ... decade. They’ve treated over 40,000 patients while carrying out ... alternative to the Paramus area. , For 2015, the ... staff of top-notch board certified physicians: Christine Milosis MD, Sandra ... new doctors will work tirelessly to carry out The ...
(Date:12/20/2014)... The aftermath of the November 24th hack on Sony ... Hollywood, but worldwide. As reported in the Los ... attack are starting a finger-pointing game which could put some ... are not the only ones affected, regular employees who had ... times ahead, agents and lawyers could be in for some ...
(Date:12/20/2014)... 20, 2014 The Twin Cities DI ... event in the nation! Over 250 financial professionals come ... information on the industry, get motivated to protect their ... people facing and overcoming the challenges of disability. , ... the nation came together to attend The 13th Annual ...
(Date:12/19/2014)... It’s very easy to become overwhelmed with the holidays ... the wayside until Christmas and the New Year are over. ... that burning desire to just escape it all and get ... Telluride with a no-fuss, affordable package. Montrose Days Inn will ... and ensure that all accommodations are met. Plus, everyone has ...
Breaking Medicine News(10 mins):Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 2Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 3Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 4Health News:The Doctor's Office Urgent Care Adds 3 New Physicians to Their Growing Medical Team 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 3Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 4Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 5Health News:The 13th Annual Twin Cities DI Day Now On Video 2Health News:The 13th Annual Twin Cities DI Day Now On Video 3Health News:Days Inn Montrose Colorado Delivers Last Minute Holiday Season Ski Getaway Accommodations 2
... , , WASHINGTON, Aug. 27 ... of Senator Edward Kennedy, a progressive political force who worked tirelessly ... and health care. He authored 2,500 pieces of legislation that helped ... , "Senator Kennedy was a champion of issues of ...
... , , , ... practices at Arizona Heart Institute (AHI) became an active member of ... in Denver. With 3,000 members, the SVS is the largest professional ... health through education, advocacy, research, and public awareness. , ...
... ... America Celebrate 100 Years of Service by Extending Reach Outside Nation,s Borders; Millions of ... on Malaria Prevention. , ... Detroit, MI (Vocus) August 27, 2009 -- The United Nations Foundation,s Nothing ...
... CHERRY HILL, N.J., Aug. 27 Nuvilex, Inc. (OTC Bulletin ... ("Last Shot") video commercial will begin airing on Monday, August ... emerging Last Shot brand awareness campaign that will ultimately include ... The video will initially be introduced to the public through ...
... arthritis woes , THURSDAY, Aug. 27 (HealthDay News) -- Stronger ... the pain of arthritic knees, a new study finds. , ... or degenerative joint disease, a major cause of disability in ... 27 million adults suffer from osteoarthritis, and 16 percent of ...
... Online Resource Provides Up-To-Date Information ... teachers, and school officials are anxiously awaiting the expected return this ... pandemic by the World Health Organization, the virus may prove a ... , To help both teachers and parents prepare for ...
Cached Medicine News:Health News:YWCA USA Mourns the Death of Senator Kennedy 2Health News:Phoenix Cardiovascular Surgeon, David J. Caparrelli, M.D. Becomes Member of the Society for Vascular Surgery 2Health News:Phoenix Cardiovascular Surgeon, David J. Caparrelli, M.D. Becomes Member of the Society for Vascular Surgery 3Health News:Nothing But Nets Teams Up With Boy Scouts of America to Fight Malaria 2Health News:Nothing But Nets Teams Up With Boy Scouts of America to Fight Malaria 3Health News:Nothing But Nets Teams Up With Boy Scouts of America to Fight Malaria 4Health News:Nuvilex Introduces Last Shot Hangover Remedy(TM) Video 2Health News:Strong Thighs May Mean Less Knee Pain for Women 2Health News:Strong Thighs May Mean Less Knee Pain for Women 3Health News:Everything Teachers and Parents Need to Know About Swine Flu 2
(Date:12/19/2014)... Ky. , Dec. 18, 2014 Baptist Health ... States to receive full Atrial Fibrillation with Electrophysiology ... Care (SCPC). Atrial fibrillation is the most common ... that in some cases can lead to stroke and possible ... United States have atrial fibrillation and the numbers ...
(Date:12/19/2014)... 2014   Aratana Therapeutics, Inc . (NASDAQ: ... on the licensing, development and commercialization of innovative ... from its pivotal field study of AT-001 (Grapiprant), ... dogs with osteoarthritis.  In the study, dogs receiving ... were statistically significant compared to placebo (p<0.05) at ...
(Date:12/19/2014)... development with the growth pace keeping at 20%-30% in last ... size of China separating membrane products ... 16.3%. It is projected that China ... 20% in the upcoming years and that the figure by ... integrated membrane industrial system has taken shape in ...
Breaking Medicine Technology:Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 2Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 4Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 5Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3
... Shows Benefits Differ from those in Adults-, ... are hospitalized for bacterial meningitis do not provide ... according to a large,multicenter study by pediatric researchers. ... hospitalized adults, for whom corticosteroids,dramatically reduced mortality., ...
... with key stakeholders on efforts to enhance ... The Association of,Clinical Research Organizations (ACRO), ... biopharmaceutical clients,policymakers, and the public in the ... in the recently formed Clinical Trial Transformation,Initiative ...
Cached Medicine Technology:Steroids Provide No Survival Benefit for Children With Bacterial Meningitis 2Steroids Provide No Survival Benefit for Children With Bacterial Meningitis 3Association of Clinical Research Organizations (ACRO) to Help Lead Clinical Trials Transformation Initiative 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: