Navigation Links
Cell division discovery could offer fresh insight into cancer
Date:1/14/2014

New findings on how the cells in our bodies are able to renew themselves could aid our understanding of health disorders, including cancer.

Scientists have explained a key part of the process of cell division, by which cells are able to keep our organs functioning properly.

They discovered a set of proteins that stabilise the sequence of events in which cells duplicate their DNA and then separate into two new cells, each identical to the original. Flaws in this delicate, complex operation can lead to cancer.

The findings help explain a fundamental process in all living things, in which cells must continually divide to keep the organism alive and well.

Researchers at the University of Edinburgh found that a set of proteins, known as the Ska complex, help anchor DNA, the form of chromosomes, by interacting with strands of cell material. Chromosomes remain attached to these strands as they are separated, in a process that helps distribute DNA correctly to the newly formed cells.

Scientists determined the structure of the relevant part of the protein complex by analysing crystals of it with lab tools and cell-based experiments. This showed how the Ska complex attaches to the strands, helping to bind the DNA material.

The study, published in Nature Communications, was carried out in collaboration with the University of Basel, Technische Universitt Berlin, and the National Institute of Immunology in New Delhi and funded by the Wellcome Trust.

Dr JP Arulanandam, of the University of Edinburgh's School of Biological Sciences, who led the work, said: "Our findings represent a milestone in resolving the mystery of how these key proteins enable new cells to separate properly and equally, in this essential process for life. The findings of our work have the potential to create new avenues in drug discovery towards fighting cancer."


'/>"/>

Contact: Catriona Kelly
Catriona.Kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh
Source:Eurekalert

Page: 1

Related medicine news :

1. Oakworks Medical, a Division of Oakworks Inc., Oakworks.com, Manufacturer of Medical Tables and Positioning Devices Announces ISO 13485 Certification
2. Catalan researchers identify a key component of cell division
3. UMass Amherst cell biologists identify new protein key to asymmetric cell division
4. New form of cell division found
5. More sex for married couples with traditional divisions of housework
6. Stemedica Forms Cardiology Division. Sergey Sikora, PhD Appointed As Division President
7. Dr. Steve Carstensen Presents First Webinar for Dental Division of American Sleep and Breathing Academy
8. MDWebPro, a division of Digital Solutions, Inc. Releases "Healthcare Social Media Week in Review #HSCM: February 11, 2013
9. Rapid Insight New Hire Launches Healthcare Predictive Analytics Division
10. MDWebPro, a division of Digital Solutions, Inc. Releases Information About a New Addition to the MDWebPro Team, Tyler Weber, Public Relations Director
11. Balboa Capital Expands Franchise Financing Division
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... Cary, North Carolina (PRWEB) , ... June 26, 2016 , ... ... the release of a new product that was developed to enhance the health of ... harvested for centuries. , The two main herbs in the PawPaws Cat Kidney ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... ... 2016 , ... Austin residents seeking Mohs surgery services, can now turn to ... Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to ... fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of ...
(Date:6/25/2016)... Aliso Viejo, California (PRWEB) , ... June 25, 2016 , ... ... preset to fit their specific project," said Christina Austin - CEO of Pixel Film ... all fully customizable and all within Final Cut Pro X . Simply select ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 According to a ... (Standard Pen Needles, Safety Pen Needles), Needle Length (4mm, ... Hormone), Mode of Purchase (Retail, Non-Retail) - Trends & ... studies the market for the forecast period of 2016 ... 2.81 Billion by 2021 from USD 1.65 Billion in ...
(Date:6/24/2016)... , June 24, 2016 VolitionRx ... of Dr. Edward Futcher to the ... effective June 23, 2016.Dr. Futcher was also appointed ... Governance Committees.  As a non-executive member of the ... and strategic counsel to VolitionRx in connection with ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced ... as its e-clinical software solution of choice.  This ... best possible value to their clients by offering ... The preferred relationship establishes nowEDC as the EDC ... for MedSource,s full-service clients.  "nowEDC has long been ...
Breaking Medicine Technology: