Navigation Links
Cell division discovery could offer fresh insight into cancer
Date:1/14/2014

New findings on how the cells in our bodies are able to renew themselves could aid our understanding of health disorders, including cancer.

Scientists have explained a key part of the process of cell division, by which cells are able to keep our organs functioning properly.

They discovered a set of proteins that stabilise the sequence of events in which cells duplicate their DNA and then separate into two new cells, each identical to the original. Flaws in this delicate, complex operation can lead to cancer.

The findings help explain a fundamental process in all living things, in which cells must continually divide to keep the organism alive and well.

Researchers at the University of Edinburgh found that a set of proteins, known as the Ska complex, help anchor DNA, the form of chromosomes, by interacting with strands of cell material. Chromosomes remain attached to these strands as they are separated, in a process that helps distribute DNA correctly to the newly formed cells.

Scientists determined the structure of the relevant part of the protein complex by analysing crystals of it with lab tools and cell-based experiments. This showed how the Ska complex attaches to the strands, helping to bind the DNA material.

The study, published in Nature Communications, was carried out in collaboration with the University of Basel, Technische Universitt Berlin, and the National Institute of Immunology in New Delhi and funded by the Wellcome Trust.

Dr JP Arulanandam, of the University of Edinburgh's School of Biological Sciences, who led the work, said: "Our findings represent a milestone in resolving the mystery of how these key proteins enable new cells to separate properly and equally, in this essential process for life. The findings of our work have the potential to create new avenues in drug discovery towards fighting cancer."


'/>"/>

Contact: Catriona Kelly
Catriona.Kelly@ed.ac.uk
44-131-651-4401
University of Edinburgh
Source:Eurekalert

Page: 1

Related medicine news :

1. Oakworks Medical, a Division of Oakworks Inc., Oakworks.com, Manufacturer of Medical Tables and Positioning Devices Announces ISO 13485 Certification
2. Catalan researchers identify a key component of cell division
3. UMass Amherst cell biologists identify new protein key to asymmetric cell division
4. New form of cell division found
5. More sex for married couples with traditional divisions of housework
6. Stemedica Forms Cardiology Division. Sergey Sikora, PhD Appointed As Division President
7. Dr. Steve Carstensen Presents First Webinar for Dental Division of American Sleep and Breathing Academy
8. MDWebPro, a division of Digital Solutions, Inc. Releases "Healthcare Social Media Week in Review #HSCM: February 11, 2013
9. Rapid Insight New Hire Launches Healthcare Predictive Analytics Division
10. MDWebPro, a division of Digital Solutions, Inc. Releases Information About a New Addition to the MDWebPro Team, Tyler Weber, Public Relations Director
11. Balboa Capital Expands Franchise Financing Division
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... 2014 Conducting Advanced Root Cause ... Skills and Innovative Techniques to Improve the Quality ... FDAnews**, Sept. 17-18, 2014 – Raleigh, NC, ... reason for 483 observations since 1997. , The ... successful CAPA program has never been more important. ...
(Date:7/30/2014)... 30, 2014 Good Neighbor Community ... an upcoming episode of Innovations with Ed Begley ... Dates and show times TBA. , In this ... Community Services’ vision to redefine the traditional approach ... dynamic services. Through passion, innovation, determination, excellence, and ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 SF Cable, ... at the lowest prices on the internet with guaranteed ... in two lengths and two colors. These lightning cords ... , The high quality SF Cable Lightning ... with digital signal delivering faster charging and syncing. Compatible ...
(Date:7/30/2014)... Hamilton Facial Plastic Surgery ... Carmel office on July 30th. After months of planning, ... to the state-of-the-art suite, located only steps away from ... allow for one-on-one patient comfort, shorter wait times, and ... Dr. Hamilton’s new office-suite will continue to provide the ...
(Date:7/30/2014)... ... ... ... , UCLA researchers interviewed people with diverticulitis ... week in the peer-reviewed journal Quality of Life Research , a UCLA team led by Dr. Brennan Spiegel interviewed patients in ...
Breaking Medicine News(10 mins):Health News:FDAnews Workshop: Conducting Advanced Root Cause Analysis CAPA Investigations, Sept. 17-18, 2014, Raleigh, NC 2Health News:FDAnews Workshop: Conducting Advanced Root Cause Analysis CAPA Investigations, Sept. 17-18, 2014, Raleigh, NC 3Health News:FDAnews Workshop: Conducting Advanced Root Cause Analysis CAPA Investigations, Sept. 17-18, 2014, Raleigh, NC 4Health News:Good Neighbor Community Services to be Featured in an Upcoming Episode of Innovations With Ed Begley, Jr. 2Health News:SF Cable Delivers Certified Lightning Cable in Multiple Sizes and Colors 2Health News:Hamilton Facial Plastic Surgery Opens New Carmel Office 2Health News:Diverticulitis patients reveal psychological, physical symptoms long after acute attacks 2Health News:Diverticulitis patients reveal psychological, physical symptoms long after acute attacks 3
... imaging technique developed at the University of Illinois ... neurological problems, such as// Chiari malformations, hydrocephalus and ... through a $1.4 million National Institutes of Health ... which draws on bioengineering, radiology and neurosurgery, will ...
... cells, seem to be obstinate, as scientists have discovered, ... a result, they are extremely// difficult to annihilate. In ... stem cells, warn researchers from the University of California, ... this tendency of stem cells that get radiation resistant ...
... stay fit, old people especially those who are 70 and ... indulge// in brain exercises, to enhance their cognitive abilities to ... ,Previous insights have indicated the benefits of engaging ... led by Sherry Willis, a human-development professor at Penn State ...
... of brain fever has killed 35 children in three months ... ,After Japanese encephalitis and viral encephalitis killed at least ... mysterious but fatal virus is prowling the region claiming children ... large so we are actually at a loss as to ...
... from olive oil, glycerine and egg yolk would ... surgery.// ,The journal of Catheterization and Cardiovascular ... led by Michael Savage, M.D., director, Cardiac Catheterization ... ,The mixture is not swallowed, Dr. Savage explains. ...
... Pradesh legislative assembly will undergo tests to screen for AIDS.// ... R. Suresh Reddy, Health Minister K. Rosaiah and leaders of ... camp held for legislators in the assembly premises. , ... should undergo the tests to set an example for others. ...
Cached Medicine News:Health News:New MRI Technique Measures Intracranial Pressure in Brain Disorder 2Health News:Olive Oil Emulsions Prevent Cardiac Bypass Surgery 2
(Date:7/30/2014)... , July 30, 2014  Today the US Surgeon ... and outdoor sun tanning or sun burns stating they can ... Surgeon, General Boris Lushniak , says that "skin cancer ... and that too much exposure to indoor and outdoor ultraviolet ... Dermatology and Aesthetic Medicine, in Boca Raton, Florida ...
(Date:7/30/2014)... 2014 Research and Markets has ... Aseptic Packaging Industry Report 2014" report to their ... The Global and Chinese Aseptic Packaging Industry Report ... state of the global Aseptic Packaging industry with a ... a basic overview of the industry including definitions, classifications, ...
(Date:7/30/2014)... July 30, 2014  InnoPharma, Inc. today announced the ... generic equivalent of Zyprexa® injection), in Canada.  Olanzapine is ... behaviors in patients with schizophrenia or bipolar I mania. ... drug, InnoPharma has entered into an agreement with Sandoz ... will make, use, sell, market and distribute Olanzapine Injection ...
Breaking Medicine Technology:Indoor and Outdoor Sun Tanning or Sun Burns Directly Linked to Deadly Melanoma Skin Cancer 2Global and Chinese Aseptic Packaging Industry Report 2014 2InnoPharma Announces Launch of Olanzapine for Injection, 10mg/vial in Canada 2
... 2011  MinuteClinic, the retail healthcare division of CVS Caremark ... provides medical services at more than 650 care locations ... clinical collaboration that includes 16 MinuteClinic locations in the ... largest provider of retail healthcare in the United States. ...
... 16, 2011 Thoratec Corporation (Nasdaq: THOR ... therapies to save, support and restore failing hearts, today ... board of directors.  "Bill brings tremendous skill, ... are delighted to add him to our board of ...
Cached Medicine Technology:Carolinas HealthCare System and MinuteClinic Enter Into Clinical Collaboration 2Carolinas HealthCare System and MinuteClinic Enter Into Clinical Collaboration 3Thoratec Announces Appointment of William A. Hawkins to Board of Directors 2Thoratec Announces Appointment of William A. Hawkins to Board of Directors 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: