Navigation Links
Cell death discovery suggests new ways to protect female fertility
Date:9/21/2012

journal Molecular Cell.

Associate Professor Jeff Kerr said that when these egg-producing cells were missing the PUMA protein, they did not die after being exposed to radiation therapy. "This might ordinarily be cause for concern because you want damaged egg cells to die so as not to produce abnormal offspring," he said. "To our great surprise we found that not only did the cells survive being irradiated, they were able to repair the DNA damage they had sustained and could be ovulated and fertilized, producing healthy offspring. When the cells were also missing the NOXA protein, there was even better protection against radiation."

"We were very excited to see healthy offspring could be produced from these cells," Associate Professor Scott said. "It means that in the future, medications that block the function of PUMA could be used to stop the death of egg cells in patients undergoing chemotherapy or radiotherapy. Our results suggest that this could maintain the fertility of these patients."

A joint leader of the study, Professor Jock Findlay, head of the Female Reproductive Biology Group at Prince Henry's Institute, said the study could also have implications for delaying menopause. "We know that the timing of menopause is influenced by how many egg cells a female has," he said. "Interventions that slow the loss of egg cells from the ovaries could delay premature menopause. As well as prolonging female fertility, such a treatment could have the potential to reduce menopause-associated health conditions, such as osteoporosis and heart disease."


'/>"/>

Contact: Vanessa Solomon
solomon@wehi.edu.au
61-393-452-971
Walter and Eliza Hall Institute
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Higher-spending hospitals have fewer deaths for emergency patients
2. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
3. Cancer Diagnosis May Raise Odds for Suicide, Heart Attack Death
4. Death From Accidental Injuries Among Kids Drops 30%: CDC
5. Opioids associated with highest risk of death
6. Study reveals major funding shortfall and high death rates for emergency laparotomy
7. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
8. Additional blood pressure screening may reduce incidence of CVD events and death by up to 3 percent
9. Groundbreaking Nigeria summit results in major commitment to reduce child deaths
10. Measles Deaths Falling Worldwide
11. On-the-job deaths steady in Michigan; Number of burn injuries underreported
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cell death discovery suggests new ways to protect female fertility
(Date:8/4/2015)... ... August 04, 2015 , ... Oriental Trading Company, ... toys, novelties, and school supplies, has developed engaging and affordable teacher supplies based ... includes student rewards, classroom decorations, crafts and educational resources featuring Carle’s vibrant ...
(Date:8/4/2015)... ... , ... It is National Psoriasis Awareness Month, and we are reminded that ... dry, itching, burning or soreness of skin that may crack or bleed. , Typically, ... right for them. Then, what is effective may stop working, so they have to ...
(Date:8/4/2015)... ... August 04, 2015 , ... The goal of looking younger ... desire for invasive surgery to achieve this ideal is not. But minimally invasive procedures ... without the high cost or lengthy recovery time, according to Valerie Goldburt, MD, ...
(Date:8/4/2015)... , ... August 04, 2015 , ... Nathan’s Famous ... takes a look small, medium, and large businesses making an impact in their industry. ... shared with viewers how the famous hot dog maker now offers a 50% ...
(Date:8/4/2015)... , ... August 04, 2015 , ... ... the most recent episode which spotlights treating depression. Depression affects millions of Americans ... "In America" wants to inform and enlighten viewers with the latest segment produced ...
Breaking Medicine News(10 mins):Health News:Oriental Trading Company Brings The World of Eric Carle Characters to Educators Through Classroom Supplies 2Health News:Oriental Trading Company Brings The World of Eric Carle Characters to Educators Through Classroom Supplies 3Health News:USA Medical Card Offers a Solution During National Psoriasis Awareness Month 2Health News:USA Medical Card Offers a Solution During National Psoriasis Awareness Month 3Health News:Considering fillers, tighteners or laser resurfacing? 2Health News:Considering fillers, tighteners or laser resurfacing? 3Health News:Considering fillers, tighteners or laser resurfacing? 4Health News:Celebrate Summer with Nathan’s Famous Original Selfie Sweepstakes 2Health News:Celebrate Summer with Nathan’s Famous Original Selfie Sweepstakes 3
... Customer Diversity and Related Strategic Opportunities , , ... has named Carolyn H. Clift as senior vice president ... be responsible for leading the company,s diversity-related strategic operations ... and fourth largest health insurer overall, HCSC has been ...
... the Implicit Association Test was introduced, its most surprising ... percent of those who took a version of the ... implicit, preference for white people compared to blacks. ... self report, or survey, measures of race bias. A ...
... and Low Metals Levels Cited as Key Reasons ... 17 Valensa International has selected Parry Nutraceuticals, ... for its range of new value-added nutrition products. ... phyto-nutrients that consumers want from their spirulina products ...
... sheds light on cause of lethal cancer, expert says, , ... genetic trait that appears to boost the risk that a ... system. , The findings don,t point toward a treatment, but ... co-author Dr. John Maris. , "We,ve learned a lot more ...
... the National Multiple Sclerosis Society - Wisconsin Chapter recognized ... Appreciation Award. The recognition commends Dr. Khatri for his ... research to treat it. , , (Logo: ... receive this recognition," says Dr. Khatri, medical director of ...
... executive director of the President,s Council on Physical Fitness ... and inventor George P. Nissen; and Olympic coach Dr. ... Achievement Awards given annually by the President,s Council. , ... to individuals whose careers have greatly contributed to the ...
Cached Medicine News:Health News:Health Care Service Corporation Names Carolyn H. Clift as Senior Vice President and First Chief Diversity Officer 2Health News:Study supports validity of test that indicates widespread unconscious bias 2Health News:Valensa Selects Parry Organic Spirulina as Ingredient of Choice for Premium Product Development 2Health News:Valensa Selects Parry Organic Spirulina as Ingredient of Choice for Premium Product Development 3Health News:Valensa Selects Parry Organic Spirulina as Ingredient of Choice for Premium Product Development 4Health News:Genes May Raise Risk of Neuroblastoma in Kids 2Health News:Genes May Raise Risk of Neuroblastoma in Kids 3Health News:Aurora Physician Recognized for Multiple Sclerosis Care 2Health News:The President's Council on Physical Fitness and Sports Announces 2009 Lifetime Achievement Award Winners 2Health News:The President's Council on Physical Fitness and Sports Announces 2009 Lifetime Achievement Award Winners 3
(Date:8/4/2015)... Aug. 4, 2015  ContraVir Pharmaceuticals, Inc. (NASDAQ: ... the development and commercialization of targeted antiviral therapies, ... Officer, will present live at VirtualInvestorConferences.com on August ... 2015 TIME: 12:15PM EDT LINK: http://tinyurl.com/aug6-pre-ctrv ... interactive online event where investors are invited to ...
(Date:8/4/2015)... Ltd. (NASDAQ: ELOS ), a leading global aesthetic device ... ended June 30, 2015. Second Quarter ... , Revenue of $73.5 million, up 14% year-over-year, or ... grew 45% year-over-year. , International sales grew 8% year-over-year, ... the EMEA region and 25% product growth in the Asia-Pacific ...
(Date:8/3/2015)... GLENWOOD, Ill. , Aug. 3, 2015  Landauer, ... personal and environmental radiation measurement and monitoring, outsourced medical ... announced it will release financial results for the fiscal ... August 10, 2015. The Company will ... August 11, 2015 at 9:00 a.m. Central Time (10:00 ...
Breaking Medicine Technology:ContraVir to Webcast Investor Presentation on August 6: VirtualInvestorConferences.com 2ContraVir to Webcast Investor Presentation on August 6: VirtualInvestorConferences.com 3Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 2Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 3Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 4Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 5Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 6Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 7Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 8Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 9Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 10Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 11Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 12Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 13Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 14Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 15Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 16Syneron Medical Reports Revenue of $73.5 Million for the Second Quarter 2015 17Landauer, Inc. Announces Date And Time For Announcement Of Fiscal Third Quarter 2015 Results And Conference Call 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: