Navigation Links
Cell Structure Helps Direct Cancer Gene 'Switch'
Date:11/14/2007

The finding might help lead to new treatments, scientists say

WEDNESDAY, Nov. 14 (HealthDay News) -- U.S. scientists say they've have uncovered a biological "switch" for key genes in cancer cells.

They found that genes in cancer cells are silenced by distinct changes in the density of structures called nucleosomes within the cells.

"The study shows for the first time exactly how genes get shut down in cancer cells. It identifies what the target looks like, so that new therapies can be designed to turn them back on," study lead author Peter A. Jones, director of the USC/Norris Comprehensive Cancer Center and Distinguished Professor at the Keck School of Medicine of USC, said in a prepared statement.

According to a statement from the university, "The study showed that silencing of transcription start sites in some cancer cells involves distinct changes in nucleosomal occupancy -- or the density of nucleosomes -- in the cell."

A process called "DNA cytosine methylation -- the addition of a group of specific chemicals to a stretch of DNA that can lock or silence a gene -- may ultimately lead to [gene] silencing by enabling the stable presence of nucleosomes at the start sites of cancer-related genes," the release said.

The study was published in the Nov. 13 issue of the journal Cancer Cell.

More information

The U.S. National Cancer Institute has more about cancer.



-- Robert Preidt



SOURCE: University of Southern California, news release, Nov. 12, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. HIDA Calls for Scrutiny of Group Purchasing Organization Distributor Fee Structure
2. Innocoll Agrees the Sale of its CollaRx(R) GENTAMICIN SURGICAL IMPLANT and European Sales and Marketing Infrastructure to EUSA Pharma
3. Purdue Pharma Selects Systech to Provide Sustainable Infrastructure for Serialization
4. Smart insulin nanostructures pass feasibility test, UT study reports
5. CRC Health Group Announces Acquisition of Durhams Structure House, Weight Loss Facility
6. Fallon Community Health Plan Selects CaseNET to Enhance Care Services Infrastructure
7. Centre De Sante et de Services Sociaux Haut-Richelieu-Rouville in Quebec Selects Alcatel-Lucent and SSP Telecom to Upgrade its Communications Infrastructure
8. Novel semiconductor structure bends light wrong way -- the right direction for many applications
9. Palmer College of Chiropractic Selects Colubris Networks to Provide Wireless Infrastructure at Three U.S. Campuses
10. Pharmos Restructures Operations in Israel
11. Best Practice Database: Complimentary Excerpt of Designing Effective Brand Teams: Structure, Governance, Performance and Operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... "FCPX editors ... customizable inside of Final Cut Pro X," said Christina Austin - CEO of Pixel ... style. Final Cut Pro X users can now reveal the media of ...
(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal ... personalized through a fitness app. The fitness app plans to fix the two major problems ... offer a one size fits all type program , They don’t eliminate all ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: ... and sells medical devices and wearable sleep respiratory products ... cooperation agreement with Hongyuan Supply Chain Management Co., Ltd. ... 20, 2016, to develop Dehaier,s new Internet medical technology ... will leverage Hongyuan Supply Chain,s sales platform to reach ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
Breaking Medicine Technology: