Navigation Links
Cell Conversion Shows Promise for Diabetes Treatment
Date:8/7/2009

But researchers must figure out how to keep new beta cells under control

FRIDAY, Aug. 7 (HealthDay News) -- European scientists have identified a transcription factor that plays a key role in the conversion of pancreas cells into insulin-producing beta cells, and the finding could lead to a new treatment for type 1 diabetes.

In tests on mice, the researchers found that when a gene called Pax4 is turned on in pancreatic cells, the cells change their identity to become beta cells. The body senses the loss of alpha cells and replaces them with new ones, which are also converted into beta cells.

With type 1 diabetes, the body destroys beta cells, causing insulin levels to drop and blood sugar levels to soar.

The study, published in the Aug. 7 issue of Cell, also shows that the pancreas is capable of beta cell regeneration.

While this approach was effective in mice, much more research has to be done before it can be determined whether it would work in humans, the researchers said.

One focus of further investigation is determining whether the alpha to beta cell conversion can be kept under control.

"Too many beta cells isn't good either," Ahmed Mansouri of the Max-Planck Institute for Biophysical Chemistry in Germany, said in a news release. "We'll need a strategy to trigger Pax4 and, at a certain point, also stop it."

More information

The American Diabetes Association has more about type 1 diabetes.



-- Robert Preidt



SOURCE: Cell Press, news release, Aug. 6, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Data Conversion Laboratory Supports Newest SPL Requirements For Life Sciences Industry
2. Blood Test Shows Statistically Significant Association With Alzheimers Disease (AD), May Predict Conversion of Mild Cognitive Impairment to AD
3. Leading University Hospital Completes System-Wide Conversion to Masimo SET(R) Pulse Oximetry
4. Patent Issued for UNIVAL(R) D3(TM) Data Conversion System
5. Covidien Canada Streamlines Integration and Processing of Fax-based Orders With GHX G-Fax(TM) Fax Conversion Service
6. Kentucky Medical Services Foundation Completes Successful Charge Capture Technology Conversion
7. Triple-S Management Corporation Announces Conversion of Class A Shares and Commencement of Class B Stock Repurchase Program
8. NJHA: Public Deserves Full Disclosure of Horizon Conversion Plan
9. Bioniche Allows Conversion of Portion of Revolving Credit Facility
10. Aurora Health Care Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology
11. MedeFile Materially Strengthens Balance Sheet Through Equity Financing and Debt Conversion Totaling $4 Million
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cell Conversion Shows Promise for Diabetes Treatment
(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his ... David Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps ... in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set ... drug or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, ... traumatic event. , Trauma sufferers tend to feel a range of emotions, from depression, ...
(Date:6/24/2016)... Francisco, CA (PRWEB) , ... June 24, 2016 ... ... CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive ... self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... , June 23, 2016 , ... on Thursday, July 7, 2016 , , , , LOCATION: ... , , , , EXPERT PANELISTS:  , , , ... Senior Industry Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and ... The global pharmaceutical industry is witnessing an exceptional era. ...
(Date:6/23/2016)... LONDON , June 23, 2016 ... environments  Oticon , industry leaders in ... the launch of Oticon Opn ™, the world,s ... world of possibilities for IoT devices.      ... Opn, Oticon introduces a number of ,world firsts,: ...
Breaking Medicine Technology: