Navigation Links
Cell Conversion Shows Promise for Diabetes Treatment
Date:8/7/2009

But researchers must figure out how to keep new beta cells under control

FRIDAY, Aug. 7 (HealthDay News) -- European scientists have identified a transcription factor that plays a key role in the conversion of pancreas cells into insulin-producing beta cells, and the finding could lead to a new treatment for type 1 diabetes.

In tests on mice, the researchers found that when a gene called Pax4 is turned on in pancreatic cells, the cells change their identity to become beta cells. The body senses the loss of alpha cells and replaces them with new ones, which are also converted into beta cells.

With type 1 diabetes, the body destroys beta cells, causing insulin levels to drop and blood sugar levels to soar.

The study, published in the Aug. 7 issue of Cell, also shows that the pancreas is capable of beta cell regeneration.

While this approach was effective in mice, much more research has to be done before it can be determined whether it would work in humans, the researchers said.

One focus of further investigation is determining whether the alpha to beta cell conversion can be kept under control.

"Too many beta cells isn't good either," Ahmed Mansouri of the Max-Planck Institute for Biophysical Chemistry in Germany, said in a news release. "We'll need a strategy to trigger Pax4 and, at a certain point, also stop it."

More information

The American Diabetes Association has more about type 1 diabetes.



-- Robert Preidt



SOURCE: Cell Press, news release, Aug. 6, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Data Conversion Laboratory Supports Newest SPL Requirements For Life Sciences Industry
2. Blood Test Shows Statistically Significant Association With Alzheimers Disease (AD), May Predict Conversion of Mild Cognitive Impairment to AD
3. Leading University Hospital Completes System-Wide Conversion to Masimo SET(R) Pulse Oximetry
4. Patent Issued for UNIVAL(R) D3(TM) Data Conversion System
5. Covidien Canada Streamlines Integration and Processing of Fax-based Orders With GHX G-Fax(TM) Fax Conversion Service
6. Kentucky Medical Services Foundation Completes Successful Charge Capture Technology Conversion
7. Triple-S Management Corporation Announces Conversion of Class A Shares and Commencement of Class B Stock Repurchase Program
8. NJHA: Public Deserves Full Disclosure of Horizon Conversion Plan
9. Bioniche Allows Conversion of Portion of Revolving Credit Facility
10. Aurora Health Care Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology
11. MedeFile Materially Strengthens Balance Sheet Through Equity Financing and Debt Conversion Totaling $4 Million
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cell Conversion Shows Promise for Diabetes Treatment
(Date:4/28/2017)... ... April 28, 2017 , ... ... could substantially improve drug safety and minimize the cost of development. In this ... channel inhibition using cell lines and for cardiac toxicity using induced pluripotent stem ...
(Date:4/28/2017)... , ... April 28, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... name the Creator responds to and which He does not. Yisrayl says with so ... one is the true name, but he says with a little Scripture, backed with a ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... ... their work assisting the Brooke Grove Foundation implement a Microsoft Dynamics GP solution ... Solutions, a leading ERP expert that specializes in long-term care, Brooke Grove now ...
(Date:4/28/2017)... ... April 28, 2017 , ... Rob Lowe is a popular actor that has ... presence to an educational purpose as the host of the “Informed” series. The program ... a recent episode, the series focuses on thyroid cancer. , Although thyroid cancer is ...
(Date:4/27/2017)... and DENVER (PRWEB) , ... April 27, 2017 ... ... Health, the nation’s leading respiratory hospital, based in Denver, Colorado, announced an agreement ... is enabled by the continuing support of the Jane and Leonard Korman Family ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017 ... stimulate an immune response in pets such as ... products are of various types such as Attenuated ... Toxoid Vaccines, DNA Vaccines and Recombinant Vaccines. Attenuated ... as virus or bacteria, which have been weakend ...
(Date:4/19/2017)... OAKS, Calif. , April 19, 2017 /PRNewswire/ ... industrial buildings it is developing at Conejo Spectrum ... , to Atara Biotherapeutics, Inc. , ... with severe and life-threatening diseases that have been ... on allogeneic T-cell therapies for cancer, autoimmune and ...
(Date:4/18/2017)... , April 18, 2017 Viverae ® , ... announce the integration of IBM ® Watson Campaign ... deliver targeted communications for a personalized experience. Through digital ... on their health in real time. The enhanced experience ... most to members, wherever they are in their journey ...
Breaking Medicine Technology: