Navigation Links
Celiac Disease Provides Clues To Solving Autoimmunity
Date:8/6/2009

DEERFIELD BEACH, Fla., Aug. 6 /PRNewswire/ -- According to an article published in Scientific America, a study of potentially fatal food-triggered disease has uncovered a process that may contribute to many autoimmune disorders.

The epidemiology of celiac disease that once was thought to be in the rage of 1 in 10,000 is now known to be in the neighborhood of 1 in 133, although not all individuals with the disease face the same set of symptoms that makes celiac and other food-related conditions so dangerous and widespread.

Dr. Alessio Fasano, Medical Director with the Center for Celiac Research at the University of Maryland Medical Center, has attributed gluten intolerance to classic gastrointestinal problems including diarrhea, bloating, and indigestion and leading to disruptions in nutrient absorption. For example, failure to properly absorb iron may lead to anemia, whereas failure to absorb folate may lead to a variety of neurological conditions. Malabsorption of specific nutrients may lead to such diverse conditions as osteoporosis, joint pain, chronic fatigue, skin lesions (eczema, psoriasis), epilepsy, dementia, schizophrenia, depression, and seizures. In addition to the above conditions, the following diseases or conditions are considered autoimmune in nature: diabetes, obesity, multiple sclerosis, breast cancer, acute ischemic heart disease, and rheumatoid arthritis.

As researchers have elucidated the precise mechanisms involved in the cascade leading to what is considered autoimmune disease (where the body actually attacks its own tissues), it is apparent that both proteins from foods as well as several genetic components are involved.

"A growing body of evidence suggests that virtually the same trio of factors underpins most, and perhaps all, autoimmune diseases: an environmental substance that is presented to the body, a genetically based tendency of the immune system to overreact to the substance, and an unusually permeable gut," said Dr. Fasano.

The crux of the process involves a leaky gut where partially digested food proteins (the environmental factor) pass or leak through the gut to interact with genetically-sensitive elements of the immune system setting off a cascade of immune reactions.

Fasano has identified a specific protein, zonulin, involved in controlling the spaces at the tight junctions in the gut wall, which is partially responsible for the leaky gut syndrome. He and other researchers are looking for drug therapies to prevent the initiation of the autoimmune cascade.

Since this cascade is triggered by a number of food proteins, another viable and proven approach is to identify the offending culprits and eliminate them from your diet. Cell Science Systems has developed a laboratory technology, the ALCAT Test, involving whole blood which is incubated with various foods to identify specific foods that trigger food intolerance. The solution then involves not eating those offending foods.

Cell Science Systems has hundreds of examples of individuals who have successfully reduced or eliminated autoimmune disease symptoms by simply avoiding certain foods for a specified period of time.

Annette, an ALCAT tester, suffered from multiple sclerosis symptoms for decades. "It was as if I was drunk but I do not drink. Turning over in bed was nearly impossible to do," said Annette. After taking the ALCAT Test and following the recommended rotation diet, her symptoms immediately began to subside. Before long, she realized it had been over a month since her last spell of symptoms. According to her husband, "It was like being married to someone else's wife."

Fasano, Alessio (2009, July 27). Celiac Disease Insights: Clues to Solving Autoimmunity. Scientific American, Retrieved on August 2, 2009 fromhttp://www.scientificamerican.com/article.cfm?id=celiac-disease-insights

About Cell Science Systems

Cell Science Systems (CSS) is a life sciences company and the worldwide market leader in food sensitivity testing as the maker of The ALCAT Test . ALCAT identifies cellular reactions to over 300 foods and chemicals. These inflammatory reactions are linked to chronic health problems like obesity and diabetes, as well as skin, heart, joint, and digestive disorders. Located in Deerfield Beach, Florida, CSS is a FDA-inspected and registered, cGMP medical device manufacturer and operates a CLIA-certified laboratory.

For more information, please call 1-800-US-ALCAT or visit http://www.ALCAT.com

This press release was issued through 24-7PressRelease.com. For further information, visithttp://www.24-7pressrelease.com.


'/>"/>
SOURCE Cell Science Systems
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Cutting Edge iPhone(TM)/iPod(R) Touch Apps Improve Quality of Life for Those With Celiac/Coeliac & Food Allergies
2. Celiac Disease Making Inroads in U.S.
3. Prometheus Launches MyCeliacID(TM), the First Do it Yourself, Saliva-Based Genetic Test Dedicated to Celiac Disease
4. Uno Chicago Grill(R) Partners With American Celiac Disease Alliance to Raise Money During Celiac Awareness Month in May
5. Toddler Health Products Help Children with Celiac Disease
6. Are vitamin supplements effective in celiac disease patients?
7. Genetic Link Between Type 1 Diabetes, Celiac Disease Seen
8. Enjoy Life Foods CEO Tells FDA Grocery Stores Remain A Dangerous Minefield for Food Allergic, Food Intolerant and Celiac Shoppers
9. Intestinal Gluten Receptor Is Gateway for Celiac Disease
10. July 2008 Mayo Clinic Womens HealthSource Highlights Vitamin D, Savvy Use of Sunscreen and Gastrointestinal Upset and Celiac Disease
11. WORLDFOODS Provides All Natural Authentic Asian Sauces That Cater to Vegetarians, Celiacs and Those With Food Allergies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s ... setting the bar too high can result in disappointment, perhaps even self-loathing. However, those ... goal. , Research from PsychTests.com reveals that behind the tendency to ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th Annual ... Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised funds ... been wounded in battle and their families. Venture Construction Group is a 2016 Silver ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and ... Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), ... Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is projected ... CAGR of 6.1% in the forecast period 2016 to ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Global MEMS Devices Medical Market Analysis 2016 - Forecast to ... The report contains up to date financial ... reliable analysis. Assessment of major trends with potential impact on ... dive analysis of market segmentation which comprises of sub markets, ...
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
Breaking Medicine Technology: