Navigation Links
Celebrex-Lipitor combo may halt prostate cancer
Date:4/14/2008

NEW BRUNSWICK, N.J. Researchers at Rutgers Ernest Mario School of Pharmacy have shown that administering a combination of the widely used drugs Celebrex (celecoxib, a nonsteroidal anti-inflammatory drug) and Lipitor (atorvastatin, a cholesterol lowering drug) stops the transition of early prostate cancer to its more aggressive and potentially fatal stage.

Prostate cancer is the second leading cause of cancer death in men in the United States, with more than a quarter-million new cases appearing each year, according to the American Cancer Society. The findings are being presented by Rutgers Professor Xi Zheng at the annual meeting of the American Association for Cancer Research in San Diego, April 14th.

In the early stage of the disease, when it is typically diagnosed, prostate cancer cells depend on androgen hormones, such as testosterone, to grow. Treatment at this stage involves either decreasing the production of the hormone or blocking its actions on the cancer cells.

Anti-androgen therapy slows the prostate cancer but eventually the cancer becomes androgen-independent, the therapy becomes ineffective and the cancer cells become more aggressive, said Xi Zheng, assistant research professor at Rutgers, The State University of New Jersey, who conducted the study.

Treatments available for the later stage cancers are not very good, said Allan Conney, director of Rutgers Susan Lehman Cullman Laboratory for Cancer Research, another researcher on the project. Oncologists employ classical chemotherapy drugs which are very toxic and dont work all that well.

Zheng and Conneys research objective was to find a way to indefinitely delay the transition to androgen-independence, prolonging the time during which the cancer would be responsive to effective, low-toxicity, anti-hormone therapy.

Zheng explained that their experiments were first conducted on cell cultures in the laboratory, where the researchers tested th
'/>"/>

Contact: Joseph Blumberg
blumberg@ur.rutgers.edu
732-932-7084 x652
Rutgers University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Green Tea, Mushroom Extract Combo Slows Sarcomas
2. Hormone Combo May Provide Reversible Male Birth Control Tool
3. LG Electronics Debuts Unique Allergen-Reducing Steam Washer/Dryer Combo
4. Combo Treatment Ups Survival When Cancer Spreads to Abdominal Lining
5. MRI/PET scanner combo
6. Treatment Combo for Pancreatic Cancer Has Limited Benefit
7. Raised Breast Cancer Risk Persists After Combo HRT Stopped
8. Combo Treatment Best for Melanoma, Advanced Ovarian Cancer
9. Drug Combo Tied to Kidney Risk With Some Cardiac Surgeries
10. Combo Therapy Shows Promise in Treating Brain Tumors
11. Combo Treatment Best for Elderly Lymphoma Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... July 31, 2015 , ... Creating one of the most modern fertility ... a visionary image that goes beyond the boundaries of fertility medicine. , As ... extraordinary heights with dependable patient support, affordable treatments, unending hope, and high fertility success ...
(Date:7/31/2015)... ... , ... The Mount Sinai Health System will work with Columbia Care LLC, ... experimental treatments. The collaboration moves into the next phase with the recent decision by ... state licenses to produce and dispense medical marijuana. , Mount Sinai and Columbia ...
(Date:7/31/2015)... ... July 31, 2015 , ... Recently, ZKB filed ... Ohio, Western Division (Case No. 3:15-cv-00397) involving the Implanon® contraceptive implant . ... migration of their Implanon® implants, inability to locate the implants, unsuccessful and invasive ...
(Date:7/31/2015)... ... 31, 2015 , ... Florida Hospital Tampa has started treating ... for targeted delivery of fluids to selected sites in the peripheral vascular system. ... with the device that provides direct, local delivery of chemotherapy to the pancreas. ...
(Date:7/31/2015)... ... 31, 2015 , ... Awarded to only the Top 10 hair transplant practices ... are the latest recipients of the Center of Clinical Excellence for ARTAS Robotic ... leaders in the science of hair transplant. , Parsa Mohebi Hair Restoration is known ...
Breaking Medicine News(10 mins):Health News:New Hope IVF Now Offers Most Affordable Assisted Reproductive Treatment in the UAE 2Health News:New Hope IVF Now Offers Most Affordable Assisted Reproductive Treatment in the UAE 3Health News:Mount Sinai to Collaborate with Columbia Care on Medical Marijuana Research 2Health News:Mount Sinai to Collaborate with Columbia Care on Medical Marijuana Research 3Health News:Can Implanon® (Etonogestrel Implant) Go Missing? Zoll, Kranz & Borgess, LLC Files Another Lawsuit on Behalf of Women with Lost or Migrated Implanon® Implants 2Health News:Can Implanon® (Etonogestrel Implant) Go Missing? Zoll, Kranz & Borgess, LLC Files Another Lawsuit on Behalf of Women with Lost or Migrated Implanon® Implants 3Health News:Florida Hospital Tampa Expands Treatment Options for Patients with Pancreatic Cancer Using New Catheter Technology 2Health News:Florida Hospital Tampa Expands Treatment Options for Patients with Pancreatic Cancer Using New Catheter Technology 3Health News:Florida Hospital Tampa Expands Treatment Options for Patients with Pancreatic Cancer Using New Catheter Technology 4Health News:Prestigious Medical Award Given To Parsa Mohebi Hair Restoration for Excellence in Hair Transplantation 2
... GENCO Supply Chain Solutions, company, to present, ... during U.S. Environmental Protection Agency,s (Region III) Pharmaceutical ... ... Capital Returns, Inc. (CRI), the,pharmaceutical industry,s leading processor of ...
... WALNUT CREEK, Calif., June 5 Longs Drug,Stores Corporation (NYSE: LDG ) today reported preliminary total retail drug,store sales for the four-week and seventeen-week periods ended ... Periods ended ... ... (4 weeks) (17 weeks), Total retail drug ...
... OSHA ,Star Site, PITTSBURGH, June 5 ... Cranberry, Pa. manufacturing plant has been designated a,national ... Occupational,Safety and Health Administration (OSHA). Fewer than 85 ... the U.S. have earned,this distinction since the VPP ...
... Closer Look at The Value of,MRIs is now ... website, http://www.msassociation.org . This three part video,features: ... first-hand,account on the experience of undergoing an MRI; ... the importance of MRIs to monitor disease,progression; and ...
... Awarded Top Juice Beverage by Health Magazine, SEATTLE, ... and,juice producers, and its Yellow Mango Orchard natural 100 ... Buys in 2008 by Health,Magazine., With the help ... products in beauty, food and fitness to the ultimate ...
... 5 Benchmarking is not a luxury;,it is an ... research,excerpt presents a survey analysis of 30 companies and ... are using benchmarking in a,difficult economy., The complete ... to benchmark, the goals of benchmarking studies, how companies ...
Cached Medicine News:Health News:Pioneering Safe Medication Return Initiative Reviewed During Pharmaceutical Disposal Summit 2Health News:Longs Reports Preliminary May Retail Drug Store Sales 2Health News:MSA Cranberry Plant Named One of Safest in Country 2Health News:MSA Cranberry Plant Named One of Safest in Country 3Health News:Photos: The Multiple Sclerosis Association of America Produces a Web Video on the Importance of MRIs 2Health News:Kagome's Yellow Mango Orchard Blended Juice Named One of America's Healthiest Buys 2Health News:Kagome's Yellow Mango Orchard Blended Juice Named One of America's Healthiest Buys 3Health News:Demonstrating the Value of Benchmarking in an Uncertain Economy 2
(Date:7/30/2015)... -- PTC Therapeutics, Inc. (NASDAQ: PTCT ) today ... the second quarter ending June 30, 2015. ... organization.  We are excited to be near the completion ... conducted with topline results expected in the fourth quarter," ... Therapeutics, Inc. "Translarna is now commercially available in 12 ...
(Date:7/30/2015)... CHENGDU, China , July 30, 2015 ... "Company"), a pharmaceutical company that specializes in the patented ... active pharmaceutical ingredients (API), provided updates regarding the notice ... MKT LLC (the "Exchange") indicating that the Company was ... set forth in Sections 134 and 1101 of the ...
(Date:7/30/2015)... 30, 2015 Eisai Inc. announced today that ... United States , European Union and ... respectively) for eribulin, for the treatment of patients with ... chemotherapy for advanced or metastatic disease. ... pivotal global Phase 3 clinical trial (Study 309), which ...
Breaking Medicine Technology:PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 2PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 3PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 4PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 5PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 6PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 7PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 8PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 9PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 10TPI Provides Update Regarding Non-Compliance with NYSE MKT Continued Listing Requirements 2Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 2Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 3Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 4Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 5
... SUNNYVALE, Calif., Oct. 24, 2011 Accuray Incorporated (Nasdaq: ... that it will report results for its first quarter of ... 8, 2011 after the market closes. A conference ... fiscal year 2012 will begin at 2:00 p.m. PST/5:00 p.m. ...
... Awarepoint Corporation , the leading provider of ... the hiring of four senior management executives to support ... solutions in hospitals and clinics. Merrie Wallace, R.N., B.S.N., ... solutions, reporting to Awarepoint CEO Jay Deady. Chris Cosgrove ...
Cached Medicine Technology:Accuray Incorporated to Report Financial Results for First Quarter of Fiscal 2012 2Awarepoint Expands Senior Management Team 2Awarepoint Expands Senior Management Team 3
We offer small and large pre-gelled Surface Electrodes suitable for EGG or EMG recordings. Surface Electrodes, Skin Preparation and Conductive Cream complete the setup for a EGG study and are essenti...
We offer small and large pre-gelled Surface Electrodes suitable for EGG or EMG recordings. Surface Electrodes, Skin Preparation and Conductive Cream complete the setup for a EGG study and are essenti...
We offer small and large pre-gelled Surface Electrodes suitable for EGG or EMG recordings. Surface Electrodes, Skin Preparation and Conductive Cream complete the setup for a EGG study and are essenti...
... We have water perfused manometric ... vector volume diagnostic tests. All ... made using clear, medical grade ... in the esophagus you will ...
Medicine Products: