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Cavities in Children Reduced Over 60 Percent by New Experimental Chewable Mints
Date:4/8/2008

Results Published in the Journal of Clinical Dentistry Demonstrate Significant Cavity-Fighting Efficacy of New Fluoride-Free BasicMints(TM)

ROSLYN HEIGHTS, N.Y. and STONY BROOK, N.Y., April 8, 2008 /PRNewswire/ -- Ortek Therapeutics, Inc. and Stony Brook University announced today that new data published in the most recent issue of the Journal of Clinical Dentistry demonstrates the effects of a new chewable mint in preventing cavities in children. This investigational product, called BasicMints(TM), contains CaviStat(R), an innovative, fluoride-free, cavity fighting complex. CaviStat is designed to mimic the profound cavity fighting benefits of saliva, by neutralizing harmful plaque acids and simultaneously promoting the remineralization of the tooth structure. The results show the children who were administered BasicMints had 62 percent fewer cavities in their molars after one year compared to children in the placebo group.

CaviStat was developed, clinically tested and patented by researchers in the Department of Oral Biology and Pathology at the State University of New York at Stony Brook and exclusively licensed to Ortek. Ortek is planning to submit an Investigational New Drug application with the U.S. Food and Drug Administration (FDA) later this year. BasicMints are not currently approved for use in the U.S. All of the components of CaviStat are naturally present in the human body.

Cavities are the most prevalent disease in children, with almost half of all children having a cavity by second grade and 80 percent having a cavity by the time they graduate from high school. Approximately 90 percent of cavities in the teeth of children occur in the biting surfaces of the back teeth. By chewing BasicMints and packing CaviStat into these vulnerable surfaces, protection is focused where most cavities form.

"Cavities affect the quality of life for millions of children every year by causing them pain, to miss school days and cost bi
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SOURCE Ortek Therapeutics, Inc.
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