Navigation Links
Cautious Optimism for New Alzheimer's Medications, Reports the Harvard Mental Health Letter
Date:10/9/2007

BOSTON, Oct. 9 /PRNewswire-USNewswire/ --- Alzheimer's disease takes a long time to develop, which suggests that it may be possible to design drugs that work early in the disease process, to delay the start of symptoms. Over the past decade, researchers have been testing a number of such "disease-modifying" drugs that target the earliest biological changes in Alzheimer's, reports the October 2007 issue of the Harvard Mental Health Letter.

None of the disease-modifying drugs now in development will cure Alzheimer's. But a number of them are currently in phase III clinical trials, the last stage before the FDA will consider approving the drugs for sale. Media interest has already begun to intensify. In June, for example, the AARP Bulletin trumpeted on its cover: "Finally, new drugs offer real hope for reversing the disease."

Two experts interviewed by the Mental Health Letter temper the optimism with caution.

The experts note that questions remain whether these drugs will be effective enough to block Alzheimer's or safe enough to be taken for a long time and with other medications.

A larger issue is whether the drugs aim at the right targets. The new disease-modifying drugs target early biological abnormalities, especially the sequence of events involved in the creation of amyloid plaques (a hallmark brain lesion in Alzheimer's). Dr. Michael Miller, editor in chief of the Harvard Mental Health Letter, notes that although most of the research effort so far has focused on this stage, researchers are still developing their understanding of how Alzheimer's develops. "Scientists are encouraged by their research into the details of the genetic and environmental causes of Alzheimer's," he says. "They look forward to identifying other interesting targets of treatment as the science evolves."

Also in this issue:

-- Depression and sleep apnea

-- The spiritual aspects of recovery

-- Alcohol abuse and dependence

-- Repeat autism screening

-- Chemistry of fear

-- What is Internet addiction?

The Harvard Mental Health Letter is available from Harvard Health Publications, the publishing division of Harvard Medical School, for $59 per year. Subscribe at http://www.health.harvard.edu/mental or by calling 1-877-649-9457 (toll free).

Media: Contact Christine Junge at Christine_Junge@hms.harvard.edu for a complimentary copy of the newsletter, or to receive our press releases directly.


'/>"/>
SOURCE Harvard Mental Health Letter
Copyright©2007 PR Newswire.
All rights reserved

Related medicine news :

1. Be cautious while on the Trampoline
2. Parents, More Cautious On Food Allergies
3. Precautious Measure Help Tolerate Nausea In Patients
4. Codeine-based painkillers to be used cautiously
5. Testing genes for disease does not cause harm to children of people with Alzheimers
6. Age-Dependent Alterations Not Specific For Alzheimers Disease
7. Killing two birds (cholesterol and Alzheimers disease) with the same stone
8. Exposure To High Aluminum Levels In Tap Water Lead To Rare Form Of Alzheimers
9. Sugar variant may make a world of difference to Alzheimers disease
10. Cancer Causing Protein May Heal Alzheimers
11. GAB2-A New Alzheimers Gene Identified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2017)... PA (PRWEB) , ... May 21, 2017 , ... Following ... 2012, New York became the first state to require that hospitals follow a protocol ... controversy in the medical community as to whether such steps would have saved Rory ...
(Date:5/19/2017)... ... 19, 2017 , ... DMG Productions is proud to announce ... Ed Begley, Jr., airing fourth quarter 2017 on FOX Business. , Based in ... supplement made from naturally occurring ingredients. Innovations will enlighten viewers on RawTrition’s all-in-one ...
(Date:5/19/2017)... ... May 19, 2017 , ... The Miller Agency, ... to families and business owners in the region, is embarking on a cooperative ... and their families. , Multiple sclerosis (MS) is a demyelinating disease that affects ...
(Date:5/19/2017)... ... May 18, 2017 , ... ML Billing, 2016 ... specialties and sizes and specializes in large group practices, is pleased to announce their ... it has also set the standard in all aspects of full-service medical billing. This ...
(Date:5/18/2017)... ... 18, 2017 , ... Dr. Kim Ross supports Stroke Awareness Month by now ... link between this condition and serious systemic health conditions including heart disease and stroke. ... in Annapolis, MD, and seeking treatment with Dr. Ross immediately may prevent bacteria from ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... 2017  A new tight-tolerance microextrusion medical tubing ... materials, is being launched by Natvar, a Tekni-Plex ... in recent years to service a wide variety ... More expensive materials such as glass and fluoropolymers ... to their ability to consistently hold tolerances. This ...
(Date:5/3/2017)... Calif. , May 3, 2017 ... of any hospital or healthcare facility. Commonly referred ... room is equipped with diagnostic imaging technology to ... of the heart. In these spaces, a team ... catheterization, balloon angioplasty, percutaneous coronary intervention, congenital heart ...
(Date:5/3/2017)... , May 3, 2017  Getinge, a ... contribute to quality enhancement and cost efficiency within ... a study of contemporary practice demonstrating that intra-aortic ... therapy for critically ill patients. The single-center, retrospective, ... newer large volume MEGA ® 50cc intra-aortic ...
Breaking Medicine Technology: