Navigation Links
Cautious Optimism for New Alzheimer's Medications, Reports the Harvard Mental Health Letter
Date:10/9/2007

BOSTON, Oct. 9 /PRNewswire-USNewswire/ --- Alzheimer's disease takes a long time to develop, which suggests that it may be possible to design drugs that work early in the disease process, to delay the start of symptoms. Over the past decade, researchers have been testing a number of such "disease-modifying" drugs that target the earliest biological changes in Alzheimer's, reports the October 2007 issue of the Harvard Mental Health Letter.

None of the disease-modifying drugs now in development will cure Alzheimer's. But a number of them are currently in phase III clinical trials, the last stage before the FDA will consider approving the drugs for sale. Media interest has already begun to intensify. In June, for example, the AARP Bulletin trumpeted on its cover: "Finally, new drugs offer real hope for reversing the disease."

Two experts interviewed by the Mental Health Letter temper the optimism with caution.

The experts note that questions remain whether these drugs will be effective enough to block Alzheimer's or safe enough to be taken for a long time and with other medications.

A larger issue is whether the drugs aim at the right targets. The new disease-modifying drugs target early biological abnormalities, especially the sequence of events involved in the creation of amyloid plaques (a hallmark brain lesion in Alzheimer's). Dr. Michael Miller, editor in chief of the Harvard Mental Health Letter, notes that although most of the research effort so far has focused on this stage, researchers are still developing their understanding of how Alzheimer's develops. "Scientists are encouraged by their research into the details of the genetic and environmental causes of Alzheimer's," he says. "They look forward to identifying other interesting targets of treatment as the science evolves."

Also in this issue:

-- Depression and sleep apnea

-- The spiritual aspects of recovery

-- Alcohol abuse and dependence

--
'/>"/>

SOURCE Harvard Mental Health Letter
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Be cautious while on the Trampoline
2. Parents, More Cautious On Food Allergies
3. Precautious Measure Help Tolerate Nausea In Patients
4. Codeine-based painkillers to be used cautiously
5. Testing genes for disease does not cause harm to children of people with Alzheimers
6. Age-Dependent Alterations Not Specific For Alzheimers Disease
7. Killing two birds (cholesterol and Alzheimers disease) with the same stone
8. Exposure To High Aluminum Levels In Tap Water Lead To Rare Form Of Alzheimers
9. Sugar variant may make a world of difference to Alzheimers disease
10. Cancer Causing Protein May Heal Alzheimers
11. GAB2-A New Alzheimers Gene Identified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... Recently, iFitDress.com, the popular online supplier of wedding dresses ... selection of black one-shoulder cocktail dresses . In addition, ... available at discounted prices, up to 70% off. ... three weeks only. You know, we have thousands of frequent ... our new items can visit our website for more details. ...
(Date:12/25/2014)... 2014 Helen Harris’ RP (Retinitis Pigmentosa) ... California after an 8 year battle with breast cancer. ... evening in her home in Woodland Hills California after ... , As the founder and volunteer ... pioneered and championed many of today's greatest breakthroughs in ...
(Date:12/25/2014)... News) -- Overeating is common during the holidays, but there ... expert says. "Don,t arrive at a party hungry. It ... you,ll be attending a party, but deprivation leads to hunger, ... Northern Westchester Hospital in Mount Kisco, N.Y., said in a ... the day and even to have a snack before attending ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 “ SmileStix ” ... which features the latest and coolest mobile applications on the ... expert and host of NewsWatch, conducted the app review and ... to create personal stickers. , The old saying goes, “A ... lot of words that can describe a single image, because ...
(Date:12/24/2014)... 25, 2014 AlignLife of Wauwatosa ... afford certain items. During the holiday season, AlignLife looks forward ... 70 toys," says Dr. Sara Mahalko-Leonhardt, owner of AlignLife. "It ... joy, knowing that we are able to give kids toys ... not been for the generosity of our patients." , The ...
Breaking Medicine News(10 mins):Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:An Application to Create Custom Stickers was Featured on NewsWatch Television on December 19, 2014 2Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2
... Southeast Florida Market, NORTH HOLLYWOOD, Calif., Aug. ... IPCM ), a leading national hospitalist,physician group practice, ... of Hospitalists of America (HOA). The acquisition,expands IPC,s ... with a network of independent physicians, who perform ...
... InteKrin Therapeutics, Inc.,a clinical stage biopharmaceutical company ... and obesity today announced it has,completed the first ... $18.25,million. The financing was led by Skyline Ventures ... Ph.D. of Skyline will join InteKrin,s Board of,Directors. ...
... (Nasdaq:,EVVV), a global endovascular device company, today announced the,appointment ... effective,immediately. Mr. Kohrs will also serve as a member ... director of ev3 from June 2005,until October 2007 at ... the completion of ev3,s acquisition of FoxHollow Technologies,Inc., ...
... the Virginia Bioinformatics Institute (VBI) at Virginia Tech have ... proteins in oomycete plant pathogens that enables the proteins ... region contains the amino acid sequence motifs RXLR and ... proteins across the membrane surrounding plant cells without any ...
... less rest linked to doubled chance of weight gain, study ... little sleep or not spending enough time in rapid eye ... and teens, a new U.S. study. , For three consecutive ... 7 to 17. They looked at total sleep time, time ...
... Study finds that older patients, concerns often go unspoken and ... ... surgery with,their orthopaedic surgeons, older patients frequently do not raise all of,their ... The Journal of Bone and Joint Surgery found that patients age,60 or ...
Cached Medicine News:Health News:IPC The Hospitalist Company Completes Acquisition of Hospitalists of America 2Health News:InteKrin Therapeutics Announces $20 Million Series C Financing 2Health News:ev3 Inc. Appoints Douglas W. Kohrs to Board of Directors 2Health News:Key to virulence protein entry into host cells discovered 2Health News:Kids Who Sleep Poorly at Risk for Being Overweight 2Health News:Video: Communication is Key to Ease Worry about Orthopaedic Surgery 2Health News:Video: Communication is Key to Ease Worry about Orthopaedic Surgery 3
(Date:12/22/2014)... 22, 2014  CytoSorbents Corporation (OTCQB:CTSOD), a critical ... purification technology to help fight deadly inflammation in ... worldwide, today announced the appointment of Dr. ... its Senior Vice President of Clinical Development, effective ... Di Russo is an accomplished pediatric cardiothoracic ...
(Date:12/22/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/h3xm6q/us ... Self-monitoring Blood Glucose Market" report to their offering. ... This market insight focuses on the developments in the ... States . Reimbursement analysis and the effects of ... more than 73 SMBG meters have been performed, based ...
(Date:12/22/2014)... Dec. 22, 2014  ConvaTec, a privately-held medical products ... been appointed Interim Chief Executive Officer of the company, ... Ken Berger .  "The Board of Directors of ... ConvaTec over the past three years," said Magnus ... "We are confident that the company is well positioned ...
Breaking Medicine Technology:CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5US Self-monitoring Blood Glucose Market 2ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2
... , , , , IRVINE, Calif., Dec. 23 ... CO-Oximetry(TM) and Measure-Through Motion and Low Perfusion pulse oximetry, today announced ... J.P. Morgan Healthcare Conference at the Westin St. Francis Hotel in ... Time. A live audiocast of the presentation will be available ...
... , , , ... leading retail pharmacy, and MinuteClinic, the largest retail health care provider ... The H1N1 vaccine is expected to be widely available in ... from supplies distributed by public health authorities. , (Logo: ...
Cached Medicine Technology:Masimo to Present at the 28th Annual J.P. Morgan Healthcare Conference 2Masimo to Present at the 28th Annual J.P. Morgan Healthcare Conference 3CVS/pharmacy and MinuteClinic to Provide H1N1 Vaccinations Coast to Coast 2CVS/pharmacy and MinuteClinic to Provide H1N1 Vaccinations Coast to Coast 3CVS/pharmacy and MinuteClinic to Provide H1N1 Vaccinations Coast to Coast 4
... Laboratories manufacturers a wide ... lenses (also known as ... Reshaping" Lenses) according to ... demanding standards of orthokeratology ...
... gas permeable contact lenses used for corneal ... nearsightedness (myopia). The patient wears the lenses ... wakening. During the day, nearsightedness is corrected ... Quadra RG contact lenses apply slight pressure ...
... Looking for a way to help your ... cardiovascular disease? Based on the outcomes ... Counterpulsation (ECP) has improved the quality of ... perform normal activities of daily living. , ...
... Considering opening your own cath lab? ... hassles, not to mention the headaches of managing ... MedCath can provide a turnkey service leaving you ... managed cath lab will provide a convenient diagnostic ...
Medicine Products: