Navigation Links
Cautious Optimism for New Alzheimer's Medications, Reports the Harvard Mental Health Letter

BOSTON, Oct. 9 /PRNewswire-USNewswire/ --- Alzheimer's disease takes a long time to develop, which suggests that it may be possible to design drugs that work early in the disease process, to delay the start of symptoms. Over the past decade, researchers have been testing a number of such "disease-modifying" drugs that target the earliest biological changes in Alzheimer's, reports the October 2007 issue of the Harvard Mental Health Letter.

None of the disease-modifying drugs now in development will cure Alzheimer's. But a number of them are currently in phase III clinical trials, the last stage before the FDA will consider approving the drugs for sale. Media interest has already begun to intensify. In June, for example, the AARP Bulletin trumpeted on its cover: "Finally, new drugs offer real hope for reversing the disease."

Two experts interviewed by the Mental Health Letter temper the optimism with caution.

The experts note that questions remain whether these drugs will be effective enough to block Alzheimer's or safe enough to be taken for a long time and with other medications.

A larger issue is whether the drugs aim at the right targets. The new disease-modifying drugs target early biological abnormalities, especially the sequence of events involved in the creation of amyloid plaques (a hallmark brain lesion in Alzheimer's). Dr. Michael Miller, editor in chief of the Harvard Mental Health Letter, notes that although most of the research effort so far has focused on this stage, researchers are still developing their understanding of how Alzheimer's develops. "Scientists are encouraged by their research into the details of the genetic and environmental causes of Alzheimer's," he says. "They look forward to identifying other interesting targets of treatment as the science evolves."

Also in this issue:

-- Depression and sleep apnea

-- The spiritual aspects of recovery

-- Alcohol abuse and dependence

-- Repeat autism screening

-- Chemistry of fear

-- What is Internet addiction?

The Harvard Mental Health Letter is available from Harvard Health Publications, the publishing division of Harvard Medical School, for $59 per year. Subscribe at or by calling 1-877-649-9457 (toll free).

Media: Contact Christine Junge at for a complimentary copy of the newsletter, or to receive our press releases directly.

SOURCE Harvard Mental Health Letter
Copyright©2007 PR Newswire.
All rights reserved

Related medicine news :

1. Be cautious while on the Trampoline
2. Parents, More Cautious On Food Allergies
3. Precautious Measure Help Tolerate Nausea In Patients
4. Codeine-based painkillers to be used cautiously
5. Testing genes for disease does not cause harm to children of people with Alzheimers
6. Age-Dependent Alterations Not Specific For Alzheimers Disease
7. Killing two birds (cholesterol and Alzheimers disease) with the same stone
8. Exposure To High Aluminum Levels In Tap Water Lead To Rare Form Of Alzheimers
9. Sugar variant may make a world of difference to Alzheimers disease
10. Cancer Causing Protein May Heal Alzheimers
11. GAB2-A New Alzheimers Gene Identified
Post Your Comments:
(Date:6/27/2016)... , ... June 27, 2016 , ... ... mental health professionals, announced today its affiliation with Tennessee Counseling Association. ... to the network of the Tennessee Counseling Association, adding exclusive benefits and promotional ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... On June ... sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, ... of the city’s history as home to some of the world’s leading providers of ...
(Date:6/25/2016)... Washington, D.C. (PRWEB) , ... June 25, 2016 ... ... will discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June ... share their work on several important health care topics including advance care planning, ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... KNOXVILLE, Tenn. , June 24, 2016 /PRNewswire/ ... market providing less invasive and more durable cerebrospinal ... million in funding.  The Series-A funding is led ... the Lighthouse Fund, and other private investors.  Arkis, ... less-invasive neurosurgical instrumentation and the market release of ...
(Date:6/23/2016)... -- Any dentist who has made an implant supported denture ... of them do not even offer this as a viable ... costs involved. And those who ARE able to offer that ... cost that the majority of today,s patients would not be ... , founder of Dental Evolutions Inc. and inventor of Implanova ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
Breaking Medicine Technology: