Navigation Links
Causes of death in AIDS patients
Date:4/28/2010

The study, by researchers from the University of Bristol and a large group of international collaborators, examined data from the Antiretroviral Therapy Cohort Collaboration (ART-CC) which involved nearly 40,000 patients who started ART between 1996 and 2006 in Europe and North America.

Of the 1,876 deaths that occurred in that time, a definitive cause of death could be assigned to 85% of cases. Overall, almost 50% of patients died from AIDS which remains the most common cause of death.

However, although during the first year of treatment with ART the majority of deaths were AIDS-related, because deaths from AIDS decline with time for patients on ART, non-AIDS-related deaths exceeded AIDS deaths after patients had been taking ART for approximately four years.

Lifestyle-related causes of death such as suicide, drug overdose and liver disease (mainly due to hepatitis) were the most frequent causes (15%) of non-AIDS deaths, and the most common non-AIDS cancer reported was lung cancer (4% of all deaths and 37% of all non-AIDS cancer deaths) which was probably associated with smoking.

Increases in rates of deaths from causes associated with aging, such as other cancers (12%) and cardiovascular disease (6.5%), imply that the process of aging will become a dominant factor in HIV mortality in the next decade.

Dr Margaret May, corresponding author on the paper published online in Clinical Infectious Diseases said, "We also found a strong inverse association of rates of AIDS death with CD4 counts a measure of immune deficiency at the time of starting ART, which supports arguments for earlier initiation of ART."

After the year 2000, the team found lower rates of AIDS deaths that may be the result of newer ART regimens having better potency and tolerability.

Interventions to address risk factors for lifestyle-related causes of death, as well as monitoring for and care of diseases associated with old age will be necessary if the full benefit of ART in decreasing mortality is to continue in the second decade of ART.


'/>"/>

Contact: Hannah Johnson
hannah.johnson@bristol.ac.uk
001-179-288-896
University of Bristol
Source:Eurekalert

Related medicine news :

1. No Surprise to David Perecman And Other Personal Injury Attorneys, Vehicles Lead All Causes of Injury at New York Hospital
2. How sunlight causes skin cells to turn cancerous
3. Economic Crisis Causes Acute Demand for Affordable Drug Addiction Treatment
4. Childhood Lead Exposure Causes Permanent Damage: Study
5. Childhood lead exposure causes permanent brain damage
6. Childhood Lead Exposure Causes Permanent Brain Damage
7. Genetic studies reveal new causes of severe obesity in childhood
8. Popular nanoparticle causes toxicity in fish, study shows
9. EPA's New Lead-Based Paint (LBP) Renovation, Repair and Painting Rule (RRP) Causes Headaches for Contractors and Property Owners Alike
10. Play Putty Blooms New Fundraising Opportunities for Schools and Causes in Need
11. What Causes A Person To Be Mentally Ill? Author Who Has Spent Decades Researching Topic Says He Has the Answer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... 2016 , ... More than 100 business, civic, community and ... the UNCF Dothan-Wiregrass Mayor’s Luncheon Dec. 9, 2016. This inaugural event, hosted by ... support to UNCF-member institutions, including Miles College, Oakwood University, Tuskegee University, Stillman College ...
(Date:12/2/2016)... ... December 02, 2016 , ... U.S. Surgeon General, Dr. Vivek Murthy, graces the ... how he was inspired to practice medicine at an early age by his father, ... than making diagnoses and prescribing medicine,” he states. “It is about building relationships with ...
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet is proud to ... which covers the innovative treatments, therapeutic technologies, and revolutionized nutrition that are helping ... prolonging life 6 years in the last 3 decades,” says Dr. Valentine Fuster, ...
(Date:12/2/2016)... ... 02, 2016 , ... Rijuven Corp launches rejiva ( http://www.rejiva.com ), a unique ... other wearable health technology on the market can deliver all that rejiva can. , ... insights about their health than the usual heart rate and steps taken”, adds Evens ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... organizations to build intelligent, connected applications, was named the best Sales Team of ... The winner announcement was made today by the Software & Information Industry Association ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... December 2, 2016 According ... Diagnostics/IVD Market by Product (Instruments, Reagents, Software), Technology ... Oncology, Cardiology, Nephrology, Infectious Diseases) - Forecast to ... valued at USD 60.22 Billion in 2016. This ... of 5.5% during the forecast period (2016-2021) to ...
(Date:12/2/2016)... 2, 2016  The Addiction Treatment Advisory Group ... Managed Care Pharmacy (AMCP), has released detailed findings ... the opioid addiction crisis, including through improved access ... ATAG,s newly released paper, "The Role of ... addresses many issues around gaps and barriers to ...
(Date:12/2/2016)... , Dec. 2, 2016 Boston Scientific ... definitive agreement to acquire certain manufacturing assets and capabilities ... (TSX: NVC) advanced biological tissue business, as well as ... of $75 million in cash. The Neovasc advanced biological ... including the Boston Scientific Lotus™ Valve System. * ...
Breaking Medicine Technology: