Navigation Links
Caucasians are at higher risk of developing Ewing's sarcoma than other races
Date:6/21/2009

The largest analysis of its kind has found that Caucasians are much more likely than people in other racial/ethnic groups to develop a rare bone and soft tissue cancer called Ewing's sarcoma. In addition, among Caucasians with this cancer, men are more likely to die than women. Published in the August 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that examining the gender and racial differences related to Ewing's sarcoma could provide a better understanding of the disease and could lead to improved treatments for patients.

Ewing's sarcoma has historically been a difficult cancer to treat, but evolving strategies with various chemotherapy drugs, surgery, and radiation have improved survival. Limited studies have identified risk factors for the disease, although it is clear that there are racial differences in incidence. Patients of various races also differ in how they are affected by the disease and how they respond to treatment. However, no reports from population-based cancer registries have verified these observations and no studies have addressed the potential impact of race on patients' health after they are diagnosed.

To get a better sense of racial differences in a large population of patients with Ewing's sarcoma, researchers led by Dr. Sean Scully of the University of Miami analyzed patient information from the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) Program, the largest source for cancer statistics in the United States. They identified individuals diagnosed with Ewing's sarcoma from 1973 to 2005 and analyzed various patient- and cancer-related characteristics.

The investigators found that Caucasians had the highest incidence of Ewing's sarcoma (155 cases per 100,000), followed by Asians/Pacific Islanders (82 cases per 100,000) and African Americans (17 cases per 100,000). Those rates indicate that Caucasians are nine times as likely to be diagnosed with the disease than African -Americans. In addition, the incidence of Ewing's sarcoma has increased significantly over the past three decades in Caucasians. While the analysis identified large differences in incidence rates among races, survival rates were similar. Finally, among Caucasiansbut not among other raceswomen had a much higher likelihood of survival than their male counterparts.

The reasons for these racial and gender differences are not clear. However, "the current study constitutes a significant step towards identification of independent demographic and clinical factors associated with improved survival and clarifies some of the associated controversies in incidence patterns that could impact on the treatment of Ewing's sarcoma," the authors wrote. Additional studies are needed to uncover the causes for racial disparities in incidence and for gender differences in survival.


'/>"/>

Contact: Claire Greenwell
claire.greenwell@cancer.org
404-417-5883
American Cancer Society
Source:Eurekalert

Related medicine news :

1. Non-Caucasians at higher risk for severe metastatic breast cancer pain
2. African Americans Show Facial Aging in Eyes Earlier Than Caucasians
3. Video: Cosmetic Procedures Up In All Ethnic Groups Except Caucasians In 2008
4. Patients with Medicaid and those lacking insurance have higher risk of advanced laryngeal cancer
5. New Study Reports High Injury Rates for Hotel Workers, Even Higher Rates for Women and Nonwhites
6. Hushed Genes Might Mean Higher Lung Cancer Risk
7. Higher death rates in kidney patients with newly recognized disease
8. Vulnerable groups are not at higher risk of physician-assisted death
9. Study Determines Breast-Specific Gamma Imaging Has Higher Specificity Than MRI in Patients With Equivocal Mammograms
10. In birds, expecting to mate leads to higher fertilization rates
11. COPD rates, higher than expected in China, will continue to grow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... NY (PRWEB) , ... May 27, 2016 , ... With ... intervention to walk, the demand for a sustainable product to aid in the rehabilitation ... and aid in the recovery of individuals with hemiplegia due to stroke. , Ekso ...
(Date:5/27/2016)... ... May 27, 2016 , ... In response ... many who are unaware of the plight of aphasia. In collaboration with the ... “Stroke Awareness” campaign. , The link between stroke and aphasia is relatively unknown, ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses and employees in ... come courtesy of leaders in the nursing and health care industry. It also provides ... associations—namely Abilene Christian University. , As the nursing industry is coming out of ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... Despite last ... meeting, expect Janet Yellen and company to wait until March 2017 for an interest ... University’s J. Mack Robinson College of Business. , “The Federal Open Market Committee (FOMC) ...
(Date:5/26/2016)... ... 2016 , ... Cabot Corporation, Pfizer, and 3M are responsible ... documents and SEC filings. A jury has returned a verdict of $32.8 ... Case No. BC588866, Los Angeles County, California. The jury awarded $22.8 million in ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... May 27, 2016 Amarantus BioScience Holdings, ... developing products for Regenerative Medicine, Neurology and Orphan Diseases, today announced ... presenting at two upcoming investor conferences: SeeThru Equity ... Avenue, New York City , NY ... Marcum MicroCap Conference   Where: Grand Hyatt Hotel, ...
(Date:5/26/2016)... , May 26, 2016   ... software and analytics, network solutions and technology-enabled ... announced it entered into a strategic channel ... of outpatient software solutions and revenue cycle ... specialty hospitals and rehabilitation clinics to optimize ...
(Date:5/25/2016)... and GERMANTOWN, Maryland , May ... QGEN ; Frankfurt Prime Standard: QIA) today announced that ... with Therawis Diagnostics GmbH to develop and commercialize predictive assays ... market PITX2 as a marker to predict effectiveness of anthracycline ... "We are pleased to partner with Therawis, which ...
Breaking Medicine Technology: