Navigation Links
Cats Can Trigger Eczema in Some Infants
Date:6/25/2008

Babies with a genetic mutation and a cat at home were more likely to develop skin condition before age of 1, study finds

WEDNESDAY, June 25 (HealthDay News) -- Infants who have a certain genetic mutation are more likely to develop eczema if there is a cat in the home, a new study suggests.

The idea that genetic mutations associated with a disease can be triggered by environmental exposures is not a new one, the researchers from Denmark and Great Britain noted.

"It's more of an example of a mechanism that's likely to happen between genes and the environment. It's sort of proof of a concept, or an idea that's been around for years," said study author Dr. Hans Bisgaard, of the Danish Pediatric Asthma Center at the University of Copenhagen. "You can have a gene for many diseases but never have the disease if you aren't exposed to triggers."

In the study, infants with the FLG mutation were studied in two groups, a high-risk group in Denmark and a representative sample in Great Britain. Children with the mutation were twice as likely to develop eczema during their first year of life. Those with the mutation and a cat in their home from the time of their birth had a further increased risk of having eczema. The study was published in the June issue of PLoS Medicine.

Eczema, or atopic dermatitis, begins in the first year of life for 65 percent of the people who have the condition, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases. About 20 percent of all infants and children have symptoms.

Bisgaard explained that the study did not determine how exposure to cats triggered the eczema, but it did demonstrate that the eczema was not an allergic reaction to cats.

"It's probably too early to tell parents to go out and shoot the cat," Bisgaard added, because the finding needs to be replicated. "What is often misleading is that people try to learn some guidance from every new scientific research study. I wouldn't take much guidance from this. I would see it as proof of a concept, the right theory we're working around."

Bisgaard said there are a number of genes that predict asthma and allergies. In the foreseeable future, it is likely "we will be able to profile a child for the risk of these diseases."

In addition to the need to confirm the results before condemning cats, other factors besides the presence of cats need to be considered as potential triggers, added Dr. Marc Riedl, section head for allergy and immunology at the David Geffen School of Medicine at the University of California, Los Angeles. "The cat ownership or exposure could potentially be a surrogate for something else that wasn't measured," he said. For example, there could be a fungal exposure associated with cats, rather than the cats, that sets off the skin reaction, Riedl explained.

Riedl agreed the importance of the study is that "it once again demonstrates gene and environmental interactions in a medical condition. This is another example of how the genetics of an individual convey some susceptibility to environmental exposures."

More information

There's more on atopic dermatitis at National Institutes of Health.



SOURCES: Hans Bisgaard, M.D., University of Copenhagen, Danish Pediatric Asthma Center; Mark Riedl, M.D., assistant professor and section head, allergy and immunology, David Geffen School of Medicine, University of California, Los Angeles; June 2008, PLoS Medicine


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
2. Pollen, Fruits, Veggies Help Trigger Oral Allergy Syndrome
3. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
4. Cell-surface sugar defects may trigger nerve damage in multiple sclerosis patients
5. Kensey Nash Reports Acceleration of Stock Awards Triggered by Shareholder Acquisition of Greater Than 20% of Outstanding Shares
6. Kaiser Permanente study: Alcohol amount, not type -- wine, beer, liquor -- triggers breast cancer
7. Going Back to School Can Trigger Eating Disorders
8. Live Christmas Trees Can Trigger Mold Allergies
9. Global Warming May Trigger Rise in Heart Deaths
10. St. Jude Researchers Identify Key Genetic Trigger of Acute Myeloid Leukemia
11. 3 Common Drugs Trigger Most ER Visits by Seniors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Cats Can Trigger Eczema in Some Infants
(Date:12/2/2016)... ... December 02, 2016 , ... ... Area in Alabama are expected to attend the UNCF Dothan-Wiregrass Mayor’s Luncheon Dec. ... scholarship funds for area students and operating support to UNCF-member institutions, including Miles ...
(Date:12/2/2016)... ... December 02, 2016 , ... Center for Autism and ... of those affected by autism spectrum disorder (ASD) and other developmental disabilities. The group, ... will give parents and other caregivers the opportunity to share stories and advice, seek ...
(Date:12/2/2016)... ... , ... With the number of pain management programs available for people suffering ... one that works for them. When an inventor from Suisun City, Calif., was unsuccessful ... to share it with others. , He developed a prototype for PRO GO MASSAGE ...
(Date:12/2/2016)... ... 02, 2016 , ... More than half of American teens report losing their ... speaking with their child about sex related topics, less than 60 percent spoke about ... to announce the launch of its second edition of the “Sexual Wellness” campaign, aiming ...
(Date:12/2/2016)... Honolulu, Hawaii (PRWEB) , ... December 02, 2016 ... ... 3, 2016 at the Hyatt Regency Waikiki Beach Resort and Spa in Honolulu, ... (CME) in the field of pain management. , The demand for supplemental ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... DUBLIN , Dec 2, 2016 Research ... Pipeline Database" newsletter to their offering. ... , , ... La Merie Publishing,s proprietary R&D Drug Pipeline Database provides 24/7 online ... therapeutic drugs on the market and on investigational drug candidates in ...
(Date:12/2/2016)... the largest share in the ECG Cables And ECG Leadwires ... remote monitoring ECG devices. On the other hand, the ... the highest growth rate during the forecast period. ... Company (U.S.), Medtronic plc ( Ireland ), Koninklijke ... Medical International Limited ( China ), held major ...
(Date:12/2/2016)... Quantum Radiology,s Mobile Breast Center (QR MBC) brings cutting-edge ... at the workplace, thereby maximizing convenience and compliance.  QR ... and SunTrust Bank, and community health groups to provide ... "I think it,s a great service for ... a mammogram without taking a large amount of time ...
Breaking Medicine Technology: