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Catheter repair of mitral valve improves heart size, symptoms
Date:4/1/2008

CHICAGO, Ill. (April 1, 2008) A catheter-mounted device that acts like a clothespin to clip together the flaps of a leaky heart valve is not only reducing the abnormal backflow of blood from the left ventricle to the left atrium, it is helping to shrink the enlarged, overworked heart and relieving symptoms of fluid overloadall without open-chest surgery. These are the one-year findings in a small group of patients enrolled in the Endovascular Valve Edge-to-Edge Repair Study (EVEREST), which is evaluating the use of the MitraClip for the treatment of mitral regurgitation (MR).

The sub-analysis is being reported today in a Late-Breaking Clinical Trials session at the SCAI Annual Scientific Sessions in Partnership with ACC i2 Summit (SCAI-ACCi2) in Chicago. SCAI-ACCi2 is a scientific meeting for practicing cardiovascular interventionalists sponsored by the Society for Cardiovascular Angiography and Interventions (SCAI) in partnership with the American College of Cardiology (ACC).

One trouble with mitral regurgitation is that the heart has to work harder, and over time, it dilates and enlarges, said James Hermiller, MD, director of the interventional fellowship at St. Vincent Heart Center of Indiana in Indianapolis. Demonstrating that the left ventricular enlargement is actually reversing itself is important objective evidence that the heart is responding favorably. It confirms that theres something real here.

Mounted on the end of a catheter, the MitraClip is threaded through the femoral vein in the groin and into the right atrium. A needle puncture in the wall separating the upper chambers of the heart enables the catheter to pass into the left atrium, where the clip is opened up like a clothespin. It is then passed through the mitral valve into the left ventricle. When the heart contracts, the flaps of the mitral valve are grasped by the clip, which is then closed, securing the edges of the valve flaps together at their centers. The
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Contact: Kathy Boyd David
pr@scai.org
717-422-1181
Weber Shandwick Worldwide
Source:Eurekalert

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