Navigation Links
Catching the early spread of breast cancer
Date:3/19/2014

ells, we could manipulate and measure things inside cells," said Mirkin, of Northwestern University. "Most people said we were wasting our time, but then out of curiosity, we put these particles in cell culture. Not only did we find that they go in, they went in better than any material known to man."

Taking advantage of their ability to enter cells easily, Mirkin's group set out to turn SNAs into a diagnostic tool the nano-flare. Recently, he and Thaxton designed these particles, which enter circulating healthy and unhealthy cells in blood samples, but light up only inside breast cancer cells.

"Nano-flares can detect just a few cancer cells in a sea of healthy cells," Mirkin said. "That's important because when cancer spreads, only a few cells may break off from the original tumor and go into the bloodstream. An added bonus of these particles is that scientists may be able to sample the live cancerous cells and figure out what therapies they might respond to."

The groups have successfully tested the nano-flares' ability to identify metastatic breast cancer cells in blood samples from animals and are currently experimenting with human samples.

"If the work pans out, a commercial diagnostic test could be available in the near future," Thaxton said.

In addition to diagnostics, it turns out nano-flares can be used to perform other unique and valuable tasks.

"Nano-flares represent the only way to measure genetic content in live cells," Mirkin said. This kind of real-time observation could be useful in many areas of research and could lead to clinical advances. For example, using nano-flares, scientists can see how drugs target different genes. This would help them develop better treatments. One company, Millipore, has already commercialized the particles for use in research labs under the name SmartFlaresTM and offers more than 1,200 variations.


'/>"/>

Contact: Michael Bernstein
214-853-8005 (Dallas Press Center, March 14-19)
202-872-6042
m_bernstein@acs.org

Contact: Katie Cottingham, Ph.D.
214-853-8005 (Dallas Press Center, March 14-19)
301-775-8455
k_cottingham@acs.org

American Chemical Society


Source:Eurekalert

Page: 1 2

Related medicine news :

1. Early detection of childhood eye cancer doesnt always improve survival, prevent eye loss
2. Primary androgen deprivation therapy ineffective for most men with early prostate cancer
3. PSA-testing and early treatment decreases risk of prostate cancer death
4. Early detection helps manage a chronic graft-vs.-host disease complication
5. Food allergy nearly doubles among black children
6. Mandatory arrest in domestic violence call-outs causes early death in victims
7. Type 1 diabetes: Vitamin D deficiency occurs in an early stage
8. Study shows preventive ovarian surgery in BRCA1 mutation carriers should be performed early
9. Frequent school moves can increase the risk of psychotic symptoms in early adolescence
10. LGB individuals living in anti-gay communities die early
11. New study explains how dense breast tissue drives the early stages of cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Today, Top10BestSEOHosting.com compares many ... USA and announces that HostMonster, Arvixe and ... Windows web hosting companies in the market. ... high quality WordPress hosting (including VPS and ... HostMonster provides outstanding customer support and a ...
(Date:9/16/2014)... (PRWEB) September 16, 2014 Not all ... they take care to make sure all their patients ... For some, this may include the newly-introduced online therapy. ... program which gives patients the opportunity to seek treatment ... can provide medical and clinical care at a distance. ...
(Date:9/16/2014)... Aspen Advisors, a U.S.-based healthcare IT consulting firm, ... high morale and collaborative culture in the ... Work For 2014.” Consulting magazine publishes the popular ... participating across all major industries, representing more than 350 ... firms were ranked in six categories - firm culture, ...
(Date:9/16/2014)... may one day be able to predict when and ... sexual functioning, thanks in part to new findings that ... American Society for Radiation Oncology,s 56th Annual Meeting on ... more than 17,000 surveys completed by men diagnosed with ... and sexual symptoms changed following each type of treatment, ...
(Date:9/16/2014)... September 16, 2014 Who:, The Pulmonary ... Medical Campus and Children’s Hospital Colorado are ... the country’s leading pulmonary hypertension association that works to find ... disease of the lungs that affects the functioning of the ... mean survivability is only 2.8 years. , What:, Colorado ...
Breaking Medicine News(10 mins):Health News:Best Windows Web Hosting Suppliers Recommended By SEO Hosting Review Site Top10BestSEOHosting.com 2Health News:Millennium Treatment Group Now Offers Online Therapy 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 3Health News:Study identifies when and how much various prostate cancer treatments will impact urinary and sexual functioning 2Health News:Study identifies when and how much various prostate cancer treatments will impact urinary and sexual functioning 3Health News:Help Fight Pulmonary Hypertension at the Colorado PH in the Park 2014 2
... Insurance Convention Expected to Draw ... Protestors to San Francisco,Delgadillo to Discuss Legal Efforts to Crack Down ... and Unfair Business Acts and Practices" of Insurers, SAN ... of,protest against health insurance corporations, Los Angeles City Attorney,Rocky Delgadillo will ...
... the team that made the discovery, Professor Christopher Rowe ... and treatment presents medical practitioners with the best opportunity ... is at an experimental stage, this work places Australia ... Rowe says. , A 2004 Access Economics report calculated ...
... marks, get set go to lane 1? , ... connection between loud sounds and reaction time are reporting findings ... the upcoming Olympics. , Led by Dave Collins, professor ... hypothesized that the loud starter,s pistol at the Olympic Games ...
... Introduces ,The Insight, First ,Webisode, Featuring Guest, Hosts, Live Call-ins, ... ... Dealing With Change, BOCA RATON, Fla., ... Florida,s first weekly webisode -- a,transformational show called "The Insight" ...
... SAN CARLOS, Calif., June 18 Nuvelo, Inc.,(Nasdaq: ... the company,s chairman,and chief executive officer, will present at ... 2008, at 1:30 p.m. ET in New,York City., ... available online via,the Investor Relations portion of Nuvelo,s website ...
... ARAY ), a global leader in the field ... officer, Euan S.,Thomson, Ph.D., is scheduled to present at ... 10:15 a.m. EDT (7:15 a.m. PDT)., A live ... the,investor relations page of the Company,s Web site at, ...
Cached Medicine News:Health News:L.A. City Attorney Rocky Delgadillo, Patient Activists to Unveil New Television Ad Targeting Health Insurers 2Health News:L.A. City Attorney Rocky Delgadillo, Patient Activists to Unveil New Television Ad Targeting Health Insurers 3Health News:Advance towards early Alzheimer's diagnosis 2Health News:Sprinters closest to starter pistol have advantage over those farther away, says study 2Health News:A South Florida Premiere 2Health News:Accuray Incorporated's CEO to Speak at Jefferies Second Annual Healthcare Conference 2
(Date:9/16/2014)... 2014 Surgeons at The Children,s Hospital of ... report the first successful use of a SynCardia temporary ... with failing Fontan circulation to bridge him to a ... old, the patient received a Fontan circulation procedure to ... "The Fontan operation is the final planned palliative operation ...
(Date:9/16/2014)... Va. , Sept. 16, 2014 ... Medical Directors Institute has simultaneously released the NAMCP ... NAMCP Medical Diagnostics Dossier Template © , which ... template formats for either medical devices or diagnostics ... aspects of each of these technology types (instead ...
(Date:9/16/2014)... , Sept. 16, 2014 The Lupus ... LLY ) today released results from UNVEIL: ... sheds light on the lupus journey and the challenges ... for lupus caregivers. The UNVEIL study, which involved over ... devastating impact lupus has on all aspects of life ...
Breaking Medicine Technology:13-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 213-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 3NAMCP Medical Directors Institute releases NAMCP Medical Technologies and Diagnostics Dossier Templates to provide model approach for medical devices or diagnostics 2"UNVEIL" Survey Reveals a Life Interrupted by Lupus 2"UNVEIL" Survey Reveals a Life Interrupted by Lupus 3"UNVEIL" Survey Reveals a Life Interrupted by Lupus 4"UNVEIL" Survey Reveals a Life Interrupted by Lupus 5
... The Netherlands, July 16 Neurofeedback - also,called EEG ... activity in order to,normalize Brain function and treat psychiatric ... 10 years, however the question,whether this treatment should be ... a study will be published in the scientific,journal ,EEG ...
... , , BOSTON and ... IIb multinational study(1) with edoxaban(2) - an investigational oral Factor ... atrial fibrillation (AF) receiving edoxaban once daily (QD) experienced fewer ... The analysis finds that bleeding associated with edoxaban is most ...
Cached Medicine Technology:New Research Shows: Neurofeedback is an 'Evidence-Based' Treatment for ADHD 2Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 2Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 3Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 4Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 5
... compatible with hood installations. ... system for 384-well plates, ... prepares large quantities of ... Wellpro also performs plate ...
... 96 is a compact and self-contained multichannel ... tip manifold can be used in a ... in the optional active wash system. ... and adds safety. Optional ...
... for low volumes. Dispenses volumes down to ... Fast throughput of less than 30 seconds ... features an intuitive user interface that provides ... dispense liquids and suspensions, beads, or cells, ...
... Personal Pipettor is a cost-effective ... pipetting needs, from reagent additions ... more. Systems are available in ... using either fixed or disposable ...
Medicine Products: