Navigation Links
Catching the early spread of breast cancer
Date:3/19/2014

ells, we could manipulate and measure things inside cells," said Mirkin, of Northwestern University. "Most people said we were wasting our time, but then out of curiosity, we put these particles in cell culture. Not only did we find that they go in, they went in better than any material known to man."

Taking advantage of their ability to enter cells easily, Mirkin's group set out to turn SNAs into a diagnostic tool the nano-flare. Recently, he and Thaxton designed these particles, which enter circulating healthy and unhealthy cells in blood samples, but light up only inside breast cancer cells.

"Nano-flares can detect just a few cancer cells in a sea of healthy cells," Mirkin said. "That's important because when cancer spreads, only a few cells may break off from the original tumor and go into the bloodstream. An added bonus of these particles is that scientists may be able to sample the live cancerous cells and figure out what therapies they might respond to."

The groups have successfully tested the nano-flares' ability to identify metastatic breast cancer cells in blood samples from animals and are currently experimenting with human samples.

"If the work pans out, a commercial diagnostic test could be available in the near future," Thaxton said.

In addition to diagnostics, it turns out nano-flares can be used to perform other unique and valuable tasks.

"Nano-flares represent the only way to measure genetic content in live cells," Mirkin said. This kind of real-time observation could be useful in many areas of research and could lead to clinical advances. For example, using nano-flares, scientists can see how drugs target different genes. This would help them develop better treatments. One company, Millipore, has already commercialized the particles for use in research labs under the name SmartFlaresTM and offers more than 1,200 variations.


'/>"/>

Contact: Michael Bernstein
214-853-8005 (Dallas Press Center, March 14-19)
202-872-6042
m_bernstein@acs.org

Contact: Katie Cottingham, Ph.D.
214-853-8005 (Dallas Press Center, March 14-19)
301-775-8455
k_cottingham@acs.org

American Chemical Society


Source:Eurekalert

Page: 1 2

Related medicine news :

1. Early detection of childhood eye cancer doesnt always improve survival, prevent eye loss
2. Primary androgen deprivation therapy ineffective for most men with early prostate cancer
3. PSA-testing and early treatment decreases risk of prostate cancer death
4. Early detection helps manage a chronic graft-vs.-host disease complication
5. Food allergy nearly doubles among black children
6. Mandatory arrest in domestic violence call-outs causes early death in victims
7. Type 1 diabetes: Vitamin D deficiency occurs in an early stage
8. Study shows preventive ovarian surgery in BRCA1 mutation carriers should be performed early
9. Frequent school moves can increase the risk of psychotic symptoms in early adolescence
10. LGB individuals living in anti-gay communities die early
11. New study explains how dense breast tissue drives the early stages of cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... School of Medicine in St. Louis helps explain why ... are more harmful than similar tumors in females. For ... diagnosed twice as often in males, who suffer greater ... long. , The researchers found that retinoblastoma protein (RB), ... less active in male brain cells than in female ...
(Date:8/1/2014)... The U.S. Food and Drug Administration announced on Friday ... fight type 2 diabetes. Jardiance (empagliflozin) "can ... to control blood sugar levels in the overall management ... of Drug Evaluation II in the FDA,s Center for ... The FDA also recommended that Jardiance be used ...
(Date:8/1/2014)... The evolving healthcare landscape presents ... At ThoughtSpot 2014, AmerisourceBergen and Good Neighbor Pharmacy’s ... resources to enhance patient care and profitability. At ... issues to give independent pharmacists the tools they ... ThoughtSpot show attendance experienced a nearly 70% increase ...
(Date:8/1/2014)... 01, 2014 Growing prevalence of ... healthcare reforms are boosting healthcare market growth, although ... discounts and increasing generic consumption is a major ... million in 2013, having grown at a Compound ... The implementation of the Health Transformation Program (Saglikta ...
(Date:8/1/2014)... 2014 (HealthDay News) -- Patients with the progressive, deadly ... have a new weapon to battle the disease, the ... The agency approved a new treatment, an inhaled spray ... killer of Americans. COPD, which is often linked to ... and emphysema. Patients with COPD may experience ...
Breaking Medicine News(10 mins):Health News:Study reveals one reason brain tumors are more common in men 2Health News:FDA Approves New Type 2 Diabetes Drug 2Health News:ThoughtSpot 2014 Inspires as General Session Concludes 2Health News:ThoughtSpot 2014 Inspires as General Session Concludes 3Health News:ThoughtSpot 2014 Inspires as General Session Concludes 4Health News:ThoughtSpot 2014 Inspires as General Session Concludes 5Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 2Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 3Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 4Health News:FDA Approves New Treatment for People With COPD 2
... ROCK, Ark., Oct. 20 Heifer International, http://www.heifer.org, ... gift alternative for the green-minded client, the hard-to-shop-for,person ... tighter gift budgets.,Heifer focuses on doing one thing ... billion people living on less than $2 a ...
... Ride Home" , ... Alameda, California (PRWEB) October 20, 2008 -- Alameda-based ... of holidays for the Safe and Sober Free Cab Ride Home program. ... in Alameda and Luxor Cab in San Francisco to provide free transportation ...
... for treatment for GERD and Erosive ... Esophagitis, ... that Takeda Global Research and,Development Center, Inc., a wholly owned United States ... agency will not be able to complete its review of the TAK-390MR ...
... Young Throats, FARMINGDALE, N.Y., Oct. 18 ... Group, Ltd. (IBG), a manufacturer,of innovative sports and ... Throat Cooler(R). This non-medicated ready-to-freeze,liquid product is a ... a 100%,drug free product to help hydrate and ...
... approximately one,in eight couples of childbearing age are infertile, ... specialist for help trying to conceive,(source: CDC)., Conceive ... who,wants to keep herself healthy so she can achieve ... are thinking about family building,and the new special issue, ...
... CALGARY, Oct. 17 /PRNewswire-FirstCall/ - The Westaim ... between its wholly owned,subsidiary iFire Technology Ltd. ... will sell its equipment, patents and intellectual ... The sale is subject to,several conditions, including ...
Cached Medicine News:Health News:Heifer International: The Greener Good for Holiday Giving 2Health News:Free Cab Rides Home for Halloween in Alameda, Oakland, Berkeley and San Francisco, California 2Health News:Free Cab Rides Home for Halloween in Alameda, Oakland, Berkeley and San Francisco, California 3Health News:FDA Adds Three Months to Review of Takeda's New Drug Application for TAK-390MR 2Health News:Integrated Beverage Group Launches Children's Throat Cooler(R) 2Health News:Integrated Beverage Group Launches Children's Throat Cooler(R) 3Health News:Conceive Magazine Introduces a Special Issue: 'The Birds, The Bees, and Modern Medicine' 2Health News:Westaim announces sale of iFire Technology Ltd. assets 2
(Date:8/1/2014)... , Aug. 1, 2014 MGC ... technologies company, announced today that it has completed ... manufacturer of cardiorespiratory diagnostic products based in Sorinnes, ... has served the European cardiorespiratory diagnostics market since ... revenues of approximately €4.7 million ($6.3 million) and ...
(Date:8/1/2014)... 1, 2014 Dyadic International, Inc. ("Dyadic") (OTCQX: ... technologies are used to develop, manufacture and sell enzymes ... and industrial enzyme industries, announced today that it will ... June 30, 2014 after market close on Thursday, August ... day at 5:00 p.m. Eastern Time to discuss those ...
(Date:7/31/2014)... , July 31, 2014  Sorrento Therapeutics, Inc. (NASDAQ: ... Mr. Amar Singh , Chief Business Officer and Executive ... natural causes on July 30. "Sorrento is deeply ... and colleague. Our immediate thoughts go to Amar,s family and ... Chief Executive Officer. Mr. Singh joined Sorrento ...
Breaking Medicine Technology:MGC Diagnostics Corporation Completes Acquisition of MediSoft SA 2MGC Diagnostics Corporation Completes Acquisition of MediSoft SA 3MGC Diagnostics Corporation Completes Acquisition of MediSoft SA 4Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 2Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 3Sorrento Announces the Unexpected Death of its Chief Business Officer 2
... Research Group (MRG), the global authority on medical ... over $30 million in 2010. Revenues, however, remained ... prices and greater market penetration of refurbished scopes. ... manufacturers are being forced to promote creative options ...
... MORRISTOWN, N.J., Oct. 27 Watson Pharmaceuticals, Inc. (NYSE: ... Watson Laboratories, Inc., filed a new drug application under ... Act (FFDCA) with the U.S. Food and Drug Administration ... 20 and 40 mg tablets.  Watson,s rosuvastatin zinc tablets ...
Cached Medicine Technology:Despite Rising Procedure Volumes, the $30 Million European Arthroscope Market Experienced Nominal Growth in 2010 2Despite Rising Procedure Volumes, the $30 Million European Arthroscope Market Experienced Nominal Growth in 2010 3Watson Confirms Crestor® Patent Challenge 2
... Tip Laryngoscopes are the most ... The articulating tip aids during ... improved view of epiglottis. Available ... styles. We guarantee your complete ...
CCR Medical conventional laryngoscopes....
CCR Medical conventional laryngoscopes....
CCR Medical conventional laryngoscopes....
Medicine Products: