Catalyst Biosciences Appoints Dr. Todd Lorenz Chief Medic... ( SOUTH SAN FRANCISCO Calif. Oct. 2...)

Catalyst Biosciences Appoints Dr. Todd Lorenz Chief Medical Officer

Date:10/28/2008

SOUTH SAN FRANCISCO, Calif., Oct. 28 /PRNewswire/ -- Catalyst Biosciences, Inc., a pioneer in the discovery and development of engineered proteases known as Alterase(TM) therapeutics, has appointed Todd Lorenz, M.D., as the company's Chief Medical Officer. Dr. Lorenz's career encompasses nearly 20 years of experience focused on the clinical development of novel medicines.

"We are excited to welcome Dr. Lorenz to the Catalyst team," said Nassim Usman, Ph.D., Chief Executive Officer of Catalyst Biosciences. "Hiring an experienced CMO to lead our development efforts is a critical step as Catalyst expands from drug discovery into clinical development. His expertise in clinical development and operations is particularly welcome as we advance our lead program, CB 813, an improved factor VIIa product for the treatment of acute bleeding in hemophiliacs, toward an IND filing in 2009."

"I am delighted to join Catalyst and have the opportunity to shape the clinical strategy for the company's pipeline of protease therapeutics," said Dr. Lorenz. "CB 813 is a highly promising compound with the potential to become a best-in-class therapeutic for hemophilia patients. Catalyst's protease therapeutics platform is poised to deliver a new class of biologics comparable in depth and scope to monoclonal antibodies."

Throughout his career, Dr. Lorenz has held leadership positions in the biotechnology and pharmaceutical industry with responsibilities across several therapeutic areas. Dr. Lorenz joins Catalyst from Johnson & Johnson (J&J), where he was Vice President and Associate Therapeutic Head for Cardiovascular Development. In this role, he contributed to clinical development efforts in several internal J&J entities including Scios, the Corporate Office of Science and Technology and Peninsula Pharmaceuticals. Dr. Lorenz served as Chief Medical Officer for Orexigen Therapeutics from 2005-2006 and was Chief Medical Officer at Corgentech from 2001-2005 where he
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