Navigation Links
Case Western Reserve to receive $19.7m to study tuberculosis treatment drugs
Date:12/8/2009

John L. Johnson, M.D., Professor of Medicine at Case Western Reserve University School of Medicine and pulmonologist at University Hospitals Case Medical Center has been awarded a 10 year, $19.7M contract from the U.S. Centers for Disease Control and Prevention (CDC) as an international clinical trials site for the Tuberculosis Trials Consortium (TBTC). TBTC, established in 1993, is a partnership of U.S. and international clinical investigators who conduct research about the diagnosis, medical treatment, and prevention of tuberculosis (TB) infection and disease.

As the principal investigator, Dr. Johnson will lead two research teams in the testing of new drugs and shorter and simpler regimens for the treatment of TB that will benefit patients worldwide.

Case Western Reserve School of Medicine will oversee international trial sites in Uganda and the Philippines. Roy Mugerwa, MBChB, MMed, will lead the TBTC site at the Uganda-CWRU Research Collaboration in Kampala, Uganda, globally, one of the most productive centers for TB research. The contract also supports the addition of a new trial site at the Tropical Disease Foundation in Makati City, Philippines, which will be under the direction of Thelma E. Tupasi, M.D. The two sites will enroll patients for clinical trials and substudies conducted by the TBTC; in addition to participating in working groups, committees and protocol teams of the Consortium; and other work to improve TB treatment for patients and TB control programs worldwide. Finally, Kathleen Eisenach, Ph.D., University of Arkansas for Medical Sciences, will provide microbiology consulting.

"The Case Western Reserve University School of Medicine has a long tradition of excellence in basic, translational and clinical research in tuberculosis and has been at the forefront of international TB research for more than two decades. My lifetime research goal is to shorten the duration of anti-TB treatment required to treat most patients," says Dr. Johnson, who is also a Professor of International Health. "This CDC contract funds TB researchers at Case Western Reserve to continue our work in conducting clinical trials to improve treatment."

According to the World Health Organization, more than nine million people around the world become sick with TB, and almost one million to two million die each year. In some areas, the disease is epidemic, with hundreds of thousands affected in nations such as China, India, and Vietnam, and in many countries of sub-Saharan Africa.

Tuberculosis is a communicable disease that can be fatal if not treated. TB usually affects the lungs, but can also affect other parts of the body, such as the brain, kidneys, or spine. New, more effective drugs and regimens for persons afflicted with TB are needed since treatment with currently available drugs requires at least six months of therapy. In addition, new drugs are urgently needed to treat patients with multi-(MDR) and extensively drug resistant (XDR)-TB, where TB germs are resistant to two or more of the best drugs currently used to treat the disease.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Related medicine news :

1. Frost & Sullivan: E-Healthcare in Western Europe Presents a Significant Market Opportunity for Wireless Technologies
2. Case Western Reserve researchers new pathway discovery published as Paper of the Week
3. Northwestern Mutual Survey Reveals That Most Americans Are Putting Their Income at Risk
4. Western diets turn on fat genes
5. Parent mentors can improve the asthmatic care of minority children, UT Southwestern researchers find
6. Holistic and Western Medicine Combined Can Fight Cancer
7. UT Southwestern receives continued NIH funding for Inner City Asthma Consortium
8. Case Western School of Medicine receives RWJF grant to establish a public health research network
9. Finding Ways for Disabled People to Participate in Research is Goal of Case Western Reserve University Nursing School Study
10. Mastery of Myeloma Continuing Education Training Program for the Multidisciplinary Care Team Set for Western Region
11. Case Western Reserve University receives $20.5 million
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work ... as “patient engagement.” The patient is doing more than filling out a survey; in ... “There is an increasing emphasis in health care and research on the importance of ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional ... action towards gender equality at their inaugural Summit in New York City in June. ... a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the Mission ... lost souls in the Philippines. “The Journey: From the Mountains to the Mission Field” ... the Bible. She has taught all ages and currently teaches a class of ladies ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed a ... and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been ... standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... 2, 2017 The Rebound mobile app is poised ... reverse the tide of prescription drug addiction. The app empowers ... intake and stepping down their dosage in a safe, controlled ... December 2017; the first 100,000 people to sign up will ... http://www.rebound-solution.com/ ...
(Date:9/25/2017)... Sept. 25, 2017   Montrium , an ... solutions, today—from the IQPC Trial Master Files & ... NL)—announced that EastHORN Clinical Services has selected ... and TMF management. EastHORN, a leading European contract ... to increase transparency to enable greater collaboration with ...
(Date:9/19/2017)... ARBOR, Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device ... precise destruction of targeted tissues, announced three leadership team developments today:   ... Stopek, PhD ... ... Veteran medical device executive ...
Breaking Medicine Technology: