Navigation Links
Case Western Reserve to receive $19.7m to study tuberculosis treatment drugs
Date:12/8/2009

John L. Johnson, M.D., Professor of Medicine at Case Western Reserve University School of Medicine and pulmonologist at University Hospitals Case Medical Center has been awarded a 10 year, $19.7M contract from the U.S. Centers for Disease Control and Prevention (CDC) as an international clinical trials site for the Tuberculosis Trials Consortium (TBTC). TBTC, established in 1993, is a partnership of U.S. and international clinical investigators who conduct research about the diagnosis, medical treatment, and prevention of tuberculosis (TB) infection and disease.

As the principal investigator, Dr. Johnson will lead two research teams in the testing of new drugs and shorter and simpler regimens for the treatment of TB that will benefit patients worldwide.

Case Western Reserve School of Medicine will oversee international trial sites in Uganda and the Philippines. Roy Mugerwa, MBChB, MMed, will lead the TBTC site at the Uganda-CWRU Research Collaboration in Kampala, Uganda, globally, one of the most productive centers for TB research. The contract also supports the addition of a new trial site at the Tropical Disease Foundation in Makati City, Philippines, which will be under the direction of Thelma E. Tupasi, M.D. The two sites will enroll patients for clinical trials and substudies conducted by the TBTC; in addition to participating in working groups, committees and protocol teams of the Consortium; and other work to improve TB treatment for patients and TB control programs worldwide. Finally, Kathleen Eisenach, Ph.D., University of Arkansas for Medical Sciences, will provide microbiology consulting.

"The Case Western Reserve University School of Medicine has a long tradition of excellence in basic, translational and clinical research in tuberculosis and has been at the forefront of international TB research for more than two decades. My lifetime research goal is to shorten the duration of anti-TB treatment required to treat most patients," says Dr. Johnson, who is also a Professor of International Health. "This CDC contract funds TB researchers at Case Western Reserve to continue our work in conducting clinical trials to improve treatment."

According to the World Health Organization, more than nine million people around the world become sick with TB, and almost one million to two million die each year. In some areas, the disease is epidemic, with hundreds of thousands affected in nations such as China, India, and Vietnam, and in many countries of sub-Saharan Africa.

Tuberculosis is a communicable disease that can be fatal if not treated. TB usually affects the lungs, but can also affect other parts of the body, such as the brain, kidneys, or spine. New, more effective drugs and regimens for persons afflicted with TB are needed since treatment with currently available drugs requires at least six months of therapy. In addition, new drugs are urgently needed to treat patients with multi-(MDR) and extensively drug resistant (XDR)-TB, where TB germs are resistant to two or more of the best drugs currently used to treat the disease.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Related medicine news :

1. Frost & Sullivan: E-Healthcare in Western Europe Presents a Significant Market Opportunity for Wireless Technologies
2. Case Western Reserve researchers new pathway discovery published as Paper of the Week
3. Northwestern Mutual Survey Reveals That Most Americans Are Putting Their Income at Risk
4. Western diets turn on fat genes
5. Parent mentors can improve the asthmatic care of minority children, UT Southwestern researchers find
6. Holistic and Western Medicine Combined Can Fight Cancer
7. UT Southwestern receives continued NIH funding for Inner City Asthma Consortium
8. Case Western School of Medicine receives RWJF grant to establish a public health research network
9. Finding Ways for Disabled People to Participate in Research is Goal of Case Western Reserve University Nursing School Study
10. Mastery of Myeloma Continuing Education Training Program for the Multidisciplinary Care Team Set for Western Region
11. Case Western Reserve University receives $20.5 million
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... Texas (PRWEB) , ... February 24, 2017 , ... Yisrayl ... that focuses on Bible Prophecy concerning this present generation. Yisrayl makes an astounding ... this current generation. He explains that the Bible details the current times so ...
(Date:2/24/2017)... Emeryville, CA (PRWEB) , ... February 24, 2017 ... ... Esparza for qualifying into the Senior International Elite division on February 12th. ... All Around divisions at the elite qualifier competition held in Las Vegas, Nevada. ...
(Date:2/23/2017)... ... February 23, 2017 , ... ... exclusively to funding innovative lymphoma research and serving the lymphoma community through a ... to the La Gorce Country Club in Miami Beach to host its Swirl: ...
(Date:2/23/2017)... ... February 23, 2017 , ... Rosica Communications, a national ... marketing, social media management, corporate communications, SEO and cause marketing, is opening an ... nearby New Hampshire, Massachusetts and Canada, Rosica will focus on expanding its footprint. ...
(Date:2/23/2017)... ... February 23, 2017 , ... ERT, a ... today announced that Premier Research, a leading clinical development service provider, has selected ... becoming increasingly complex, due in part to an array of circumstances including the ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Im Rahmen seiner Schlüsselwachstumsstrategie arbeitet die ... südwestlichen chinesischen Provinz Guizhou, 2017 mit dem Angebot von Anreize ... der Entwicklung einer eingebetteten Hightech-Schlüsselindustrie. Foto - ... ... ...
(Date:2/23/2017)... , Feb. 23, 2017 AcelRx ... focused on the development and commercialization of innovative ... announced that it will release fourth quarter and ... March 2nd, 2017. AcelRx management will host an ... (1:30 p.m. Pacific Time) on March 2 nd ...
(Date:2/23/2017)... , February 23, 2017 According ... by Product (X-ray Imaging Digital, Analog), MRI (Closed, Open), ... MSK, Cardiology, Oncology), End User (Hospitals, Imaging Centers) - ... studies the global market over the forecast period of ... ~USD 36.43 Billion by 2021, at a CAGR of ...
Breaking Medicine Technology: