Navigation Links
Case Western Reserve receives $1.6M to study tumor cells and immune cell detection
Date:3/31/2011

Case Western Reserve University School of Medicine has received a $1.6 million grant from the National Cancer Institute (NCI) to study how tumor cells avoid detection by the body's immune system, allowing cancer to develop and spread.

The five-year National Institutes of Health grant will enable researchers led by Alex Y. Huang, MD, PhD, assistant professor of pediatrics, pathology, and biomedical engineering at the School of Medicine, and a hematologist and oncologist at Rainbow Babies & Children's Hospital at University Hospitals Case Medical Center, to examine "immune tolerance." The process keeps tumor cells from being detected by the immune system, even when they invade draining lymph nodes, a place where primary immune activation and surveillance take place. Lymph nodes are part of the body's lymphatic system, which fights off viruses, bacteria, and other disease-causing agents.

The study will also test whether modifying the environment in which tumor and immune cell interactions take place, using a group of proteins called inflammatory chemokines, will activate unresponsive immune cells into fighting off cancer. Using inflammatory chemokines as part of the anti-tumor strategies is a novel approach to cancer treatment.

"This research will provide greater insight into the potential therapeutic utilities of inflammatory chemokines, thereby providing a new direction for the development of immunotherapies that are capable of fighting cancer at the most basic cellular level," Dr. Huang says, who is also an associate member of the Case Comprehensive Cancer Center at the School of Medicine and director of the Pediatric Hematology-Oncology Fellowship Program at Rainbow Babies & Children's Hospital. "Any effective cellular immunotherapy must enhance long-term tumor immunity, effectively concentrating immune cells and priming them to destroy cancer cells anywhere in the body over long periods of time."

Researchers will work to
'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. UT Southwestern research advances fight against kidney cancer
2. Annual sonograms are needed to verify correct IUD position, UT Southwestern obstetricians say
3. Northwestern Medicine multiple sclerosis program earns national designation
4. UT Southwestern receives $36.7 million for cancer research
5. Foster parents receive more support than kinship caregivers, UT Southwestern study finds
6. UT Southwestern launches clinical trial for treatment of breast cancer using CyberKnife
7. Homogeneous tuberculosis treatment ineffective in children, UT Southwestern researchers find
8. Western Diet May Raise Risk of Kidney Function Decline
9. Helping others helps alcoholics stay on the road to recovery, Case Western Reserve shows
10. Case Western Reserve receives $7.8M to study manic symptoms in children
11. Case Western Reserve and Athersys show regenerative benefit of MultiStem after spinal cord injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... Permanent atrial fibrillation (AF) doubles the risk of stroke ... than 6 000 patients presented at ESC Congress today ... that a simple clinical assessment of the type of ... , Ischaemic stroke is the second cause of death ... and many more disabled patients each year. Annual direct ...
(Date:9/1/2014)... York (PRWEB) September 01, 2014 ... retrieve, organize and analyze biological and genetic data. ... the activity of developing software tools to generate ... to be confused with biological computation. While bioinformatics ... understanding of biology can its related concepts, biological ...
(Date:9/1/2014)... Top10BestSEOHosting.com has recently compared many web ... carefully, Top10BestSEOHosting.com is here to announce that JustHost, ... suppliers in 2014. , JustHost ( http://www.justhost.com/track/seohosts ) ... shared hosting plan. The company’s approach to hosting ... affordable, accessible and powerful enough for anyone to ...
(Date:9/1/2014)... San Diego, CA (PRWEB) September 01, 2014 ... website daily regarding all the latest information from the ... , The US FDA announced on August 28, ... are recalled (Class I) as the device ... FDA, the DePuy Synthes Craniomaxillofacial (CMF) Distraction System is ...
(Date:9/1/2014)... Mahwah, NJ (PRWEB) September 01, 2014 ... disorder (NEAD) is a psychological disorder that can have ... look very much like epileptic seizures however, they are ... rather by emotional triggers. It is estimated that ... than those affected by multiple sclerosis. , ...
Breaking Medicine News(10 mins):Health News:Permanent AF doubles risk of stroke compared to paroxysmal AF 2Health News:Bioinformatics Market: A fusion of Computers and Biological Data 2Health News:Bioinformatics Market: A fusion of Computers and Biological Data 3Health News:Bioinformatics Market: A fusion of Computers and Biological Data 4Health News:Why Top10BestSEOHosting.com Calls Them Great Web Hosting Suppliers 2Health News:DePuy Synthes Craniomaxillofacial Distraction System Recalled (Class I): AttorneyOne Monitors and Keeps Consumers Informed 2Health News:DePuy Synthes Craniomaxillofacial Distraction System Recalled (Class I): AttorneyOne Monitors and Keeps Consumers Informed 3Health News:The Northeast Regional Epilepsy Group (NEREG) Offers First Conference on Psychogenic Non-epileptic Seizures (PNES) on September 20, 2014 in New Jersey 2
... Up 23% - Gross Profit Decreases ... - Pre-Tax Income ... - Net income $888,000; EPS $.05, MORTON GROVE, Ill., ... beverage,called kefir, announced today for the first quarter ended March 31, 2008,total sales increased 23% ...
... to Pain and Injury Risk, ALEXANDRIA, Va., May ... that biking to work not only provides,excellent health benefits ... Bike to Work Day on Friday, May 16, the ... lower their,risk of injury by ensuring that their bicycles ...
... /PRNewswire-FirstCall/ - LMS Medical Systems,(TSX:LMZ), a healthcare technology ... systems for obstetrics, today announced that it has,entered ... LLC,(Regional) of New Jersey to license CALM Shoulder ... Obstetricians and Gynecologists in New Jersey,serving over 200,000 ...
... are more likely to suffer from a larger number ... more than 5,000 men and women published in the ... Researchers hope the results will help clinicians to understand ... more effectively. , According to the Boston Area ...
... OmniGuide, Inc., the developer,of the first and ... in,minimally invasive surgery, today announced the closing of ... Group, a healthcare venture capital,and private equity firm, ... Ray Stata, Stata Venture Partners, 3i, Argonaut,Ventures, ESI, ...
... N.J., May 15 Chemical sourcing executives,from the ... issues during the Pharma ChemOutsourcing Conference on September ... that such an impressive gathering of,industry management has ... of materials and services to support R & ...
Cached Medicine News:Health News:Lifeway Foods Reports Record 1st Quarter 2008 Results 2Health News:Lifeway Foods Reports Record 1st Quarter 2008 Results 3Health News:Lifeway Foods Reports Record 1st Quarter 2008 Results 4Health News:Physical Therapists Offer Tips for Proper Bike Fit in Support of National Bike to Work Day 2Health News:Physical Therapists Offer Tips for Proper Bike Fit in Support of National Bike to Work Day 3Health News:Physical Therapists Offer Tips for Proper Bike Fit in Support of National Bike to Work Day 4Health News:LMS CALM Shoulder Screen(TM) selected by New Jersey physician group to minimize obstetrical risks 2Health News:LMS CALM Shoulder Screen(TM) selected by New Jersey physician group to minimize obstetrical risks 3Health News:Obesity and unhealthy lifestyles linked to more complex urinary problems 2Health News:Obesity and unhealthy lifestyles linked to more complex urinary problems 3Health News:Obesity and unhealthy lifestyles linked to more complex urinary problems 4Health News:OmniGuide(R) Secures $25 Million in Funding to Support Continued Growth and New Market Penetration 2Health News:OmniGuide(R) Secures $25 Million in Funding to Support Continued Growth and New Market Penetration 3Health News:11 Pharmaceutical Titans Headline Chemistry Outsourcing Conference Program in September in New Jersey 2
(Date:8/29/2014)... According to the new ... (Equipment, Reagent, Primer, Probe, Custom Oligos), End-User (Research, ... Synthesis, NGS, DNA, RNAi) - Global Forecast to ... Market is expected to reach $1,712.1 Million by ... a CAGR of 9.8% from 2014 to 2019.. ...
(Date:8/29/2014)... -- Research and Markets has announced the ... 2014-2018" report to their offering. ... results in demyelination, axonal transection, and neurodegeneration. The myelin ... the immune system, which targets neurons within the central ... in which the damage of the myelin sheath causes ...
(Date:8/29/2014)... British Columbia and MENLO PARK, ... DelMar Pharmaceuticals, Inc. (OTCQB: DMPI) ("DelMar" "the ... fiscal year-end financial statements.  The Company recently changed its ... facilitate an application to list its common stock on ... DelMar,s financial statements as filed with the ...
Breaking Medicine Technology:Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 3Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 4Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 2Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5
... ... Dysmenorrhea Pain Medication, HOBOKEN, N.J., June 18 A ... periods,affecting millions of women each year, can be reduced naturally ... maritime,pine tree. The multi- center field study, published in the ...
... the Need for Testosterone Screening in At-Risk ... ... from a 12-month,international, multi-center study showed that treatment for low,testosterone with ... and sexual function among,hypogonadal men with Type 2 diabetes and/or Metabolic ...
Cached Medicine Technology:New Study: Pine Bark Significantly Reduces Menstrual Pain 2New Study: Pine Bark Significantly Reduces Menstrual Pain 3Novel Testosterone Gel Significantly Improves Insulin Sensitivity and Sexual Function in Hypogonadal Men With Type 2 Diabetes and Metabolic Syndrome 2Novel Testosterone Gel Significantly Improves Insulin Sensitivity and Sexual Function in Hypogonadal Men With Type 2 Diabetes and Metabolic Syndrome 3
Ideal for nucleus manipulation during phacoemulsification. Also used for manipulating and rotating IOLs within the anterior chamber. Round knurled handle...
Short, narrow paddle angled 45 degree inserts through the side port stab incision and is ideal for effective manipulation of the lens during anterior chamber phacoemulsification....
Nucleus divider with 1.25 mm tip and blade offset at a 60 degree angle is ideal for performing the "Phaco Chop" technique. Round knurled handle. Manufactured in titanium....
#2 10 mm hook. Flat serrated handle with polished finish. Overall length: 5.5 inches....
Medicine Products: