Navigation Links
Case Western Reserve and Penn State investigators inhibit corneal inflammation
Date:6/11/2008

Researchers from the Case Western Reserve University School of Medicine and Penn State Hershey College of Medicine identified a novel therapeutic that reduces sterile inflammation within the cornea. Published in the June issue of the Journal of Leukocyte Biology, Dr. Eric Pearlman and Dr. Mark Kester identified a novel ceramide, a natural compound that when delivered in nano-sized packages reduces corneal haze, corneal thickening and inflammation. These nano-sized packages permit the use of ceramide as an eye drop. Drs. Pearlman and Kester are working towards human trials with this reagent.

Inflammation and corneal infections are potential side effects of contact lens wear, especially with extended wear contact lenses that remain in the eye for up to two weeks. Given that there are some 30 million contact lens wearers in the United States and 140 million worldwide, even a small percent of side effects (<5%) such as irritation or pain has an enormous economic effect on contact lens use, as wearers who experience will stop wearing lenses. Although steroids are effective in blocking inflammatory responses and can ease irritation, the major side effects of steroid use include increased ocular pressure that can lead to development of glaucoma. An alternate anti-inflammatory approach is therefore an important clinical target for Drs. Pearlman and Kester.

"This research is an important finding within the visual sciences and an excellent example of collaboration between two highly regarded institutions," said Eric Pearlman, Ph.D., Professor and Director of Research, Case Western Reserve University School of Medicine's department of ophthalmology.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Page: 1

Related medicine news :

1. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
2. UT Southwesterns obesity research receives $22 million NIH Roadmap grant
3. Evanston Northwestern Healthcare Wins Award For Patient Safety
4. Physician Team at Northwestern Memorial Performs Rare Oral Gallbladder Removal
5. David Ward Joins OrthoSynetics(TM) as Western Region Sales Manager
6. UT Southwestern scientist receives NIH Directors New Innovator Award
7. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
8. 2 UT Southwestern researchers elected to National Academy of Sciences Institute of Medicine
9. UT Southwestern researcher named Howard Hughes Medical Institute investigator
10. Nursing Scholarships Offered by Western Governors University for Masters Degree Programs
11. Northwestern Memorial Hospital Completes Move Into Its New Prentice Womens Hospital
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/26/2017)... ... July 26, 2017 , ... A major challenge many labs face is a ... and a lengthy freeze dry cycle are a few common challenges that can overcome ... well as new accessories and advancements in laboratory freeze dryers that will improve quality ...
(Date:7/26/2017)... St. Petersburg, FL (PRWEB) , ... July 27, 2017 , ... It's time to ... "We loaded the club with great benefits," says Kathy Heshelow, founder of Sublime Naturals and ... a full size therapeutic-grade essential oil each month, mailed by the 5th. , ...
(Date:7/26/2017)... Jupiter, Florida (PRWEB) , ... July 26, 2017 ... ... care for dogs and cats has opened in Jupiter. The state of ... patients (cardiology) and class leading treatments with a goal of providing heart patients ...
(Date:7/26/2017)... ... July 26, 2017 , ... Wendy M. Musielak, a partner at the ... as DuPage County Bar Association’s third Vice President earlier this year. She will serve the ... of the second Vice President, in accordance with the organization’s by-laws. , Musielak ...
(Date:7/25/2017)... SPRINGS, California (PRWEB) , ... July 25, 2017 , ... ... involve cranking up the air conditioner — think homemade gourmet ice cream, sparkling pools, ... inside a gift shop featuring fun mugs, journals, and other must-have knick knacks. Ice ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... and EDMONTON, Alberta , ... scientists and the University of Alberta in ... data in Nature,s partner journal, Schizophrenia 1 , ... predict instances of schizophrenia with 74% accuracy. This ... severity of specific symptoms in schizophrenia patients with ...
(Date:7/21/2017)... 21, 2017 Did you know that PhRMA member companies ... that combined spending on brand medicines, generics and the supply chain ... accounting for just half of this (7 percent)? Or that ... the world,s venture capital investments in high-growth biopharmaceutical startups? ... ...
(Date:7/17/2017)... -- MedX Holdings, Inc., the manufacturer and global distributor of ... today announced the national roll out of its MedX ... standard for the treatment of low back injuries and ... How it works: MedX ... who prescribe the MedX Home Back Machine Program for ...
Breaking Medicine Technology: