Navigation Links
Case Western Reserve and Penn State investigators inhibit corneal inflammation
Date:6/11/2008

Researchers from the Case Western Reserve University School of Medicine and Penn State Hershey College of Medicine identified a novel therapeutic that reduces sterile inflammation within the cornea. Published in the June issue of the Journal of Leukocyte Biology, Dr. Eric Pearlman and Dr. Mark Kester identified a novel ceramide, a natural compound that when delivered in nano-sized packages reduces corneal haze, corneal thickening and inflammation. These nano-sized packages permit the use of ceramide as an eye drop. Drs. Pearlman and Kester are working towards human trials with this reagent.

Inflammation and corneal infections are potential side effects of contact lens wear, especially with extended wear contact lenses that remain in the eye for up to two weeks. Given that there are some 30 million contact lens wearers in the United States and 140 million worldwide, even a small percent of side effects (<5%) such as irritation or pain has an enormous economic effect on contact lens use, as wearers who experience will stop wearing lenses. Although steroids are effective in blocking inflammatory responses and can ease irritation, the major side effects of steroid use include increased ocular pressure that can lead to development of glaucoma. An alternate anti-inflammatory approach is therefore an important clinical target for Drs. Pearlman and Kester.

"This research is an important finding within the visual sciences and an excellent example of collaboration between two highly regarded institutions," said Eric Pearlman, Ph.D., Professor and Director of Research, Case Western Reserve University School of Medicine's department of ophthalmology.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Page: 1

Related medicine news :

1. Single-incision belly-button surgery to remove kidney performed first at UT Southwestern
2. UT Southwesterns obesity research receives $22 million NIH Roadmap grant
3. Evanston Northwestern Healthcare Wins Award For Patient Safety
4. Physician Team at Northwestern Memorial Performs Rare Oral Gallbladder Removal
5. David Ward Joins OrthoSynetics(TM) as Western Region Sales Manager
6. UT Southwestern scientist receives NIH Directors New Innovator Award
7. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
8. 2 UT Southwestern researchers elected to National Academy of Sciences Institute of Medicine
9. UT Southwestern researcher named Howard Hughes Medical Institute investigator
10. Nursing Scholarships Offered by Western Governors University for Masters Degree Programs
11. Northwestern Memorial Hospital Completes Move Into Its New Prentice Womens Hospital
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... ... , ... California Southern University has named Dr. Steven Beazley University President. ... as a core faculty member, teaching master’s and doctoral courses in the university’s School ... University, where he earned his Doctor of Psychology degree in 1998. Dr. Beazley also ...
(Date:1/16/2017)... ... , ... With the Grand Opening Event planned for February 3, 2017, the ... and the general public. Built in five months by Centerpoint, the 60,000 square foot ... or pickleball courts. The space is also suitable for indoor soccer and football training. ...
(Date:1/16/2017)... New York (PRWEB) , ... January 16, 2017 ... ... SightMD today announced the addition of Victor Giamos, MD to their ... of SightMD and Managing Partner at North Shore Eye Care, a division of ...
(Date:1/16/2017)... ... January 16, 2017 , ... ... partnership with an innovator in the wheelchair accessibility industry, BraunAbility . Incentive ... salespeople to sell wheelchair accessible vehicles. With this new incentive plan, BraunAbility plans ...
(Date:1/16/2017)... ... January 16, 2017 , ... Board-certified oculoplastic surgeon ... , the official journal of The American Society for Aesthetic Plastic Surgery, in ... procedure is designed to correct drooping, retracted lower eyelids, which usually result from ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... BAUDETTE, Minn. , Jan. 17, 2017 /PRNewswire/ ... ) today announced the appointment of Karen Quinn ... January 17, 2017.  Karen ... years of leadership experience in Global Regulatory Affairs, ... biologically-derived active pharmaceutical ingredients.  Dr. Quinn worked most ...
(Date:1/17/2017)... pioneer in no-touch UV disinfection has now been validated by ... for "total room ultraviolet disinfection," was the device of choice ... study which was recently published in The Lancet ... transmission of four major superbugs by a cumulative 30 percent. ... we have been committed to innovation and the science behind ...
(Date:1/16/2017)... Research and Markets has announced the addition ... to their offering. ... Global multiple myeloma drugs market to grow at a CAGR ... covers the present scenario and the growth prospects of the global ... the report considers the revenue generated from the sales of branded ...
Breaking Medicine Technology: