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Case Western Reserve University joins BrainGate clinical trial
Date:2/21/2013

the clinical trial in Cleveland, is the medical director of the Deep Brain Stimulation Program and Dr. Miller is the director of Functional and Restorative Neurosurgery at UH Case Medical Center.

To begin this study, called the BrainGate2 pilot clinical trial, Dr. Miller will implant a tiny sensor (about the size of a baby aspirin) containing 96 electrodes to record the activity of neurons in the surface layers of the brain. In people with paralysis, the BrainGate2 study has previously shown that the brain can continue to generate patterns of activity when a person attempts or imagines movement. The system used to record and translate these patterns is called a brain-computer interface.

The Case Western Reserve BrainGate2 site is part of a larger clinical trial assessing the safety and feasibility of the brain-computer interface system in people with paralysis. BrainGate technology was developed in the laboratory of John Donoghue, Ph.D. at Brown University, and the overall trial is directed by Leigh R. Hochberg, MD, Ph.D., of the Massachusetts General Hospital, Brown University, the Center for Neurorestoration and Neurotechnology at Providence VA Medical Center, and Harvard Medical School.

The BrainGate collaboration, recently joined by Stanford University, has used the investigational BrainGate technology to record the patterns of brain activity in people with paralysis. As reported in journals such as Nature and the Journal of Neural Engineering, participants have been able to use the BrainGate system to move a computer cursor or operate an advanced prosthetic arm just by thinking about it.

"By launching a BrainGate trial site with our long-time colleagues at Case Western, we have the opportunity to work toward the long-term dream for this research to reconnect a disconnected nervous system, and to one day allow someone with cervical spinal cord injury to regain intuitive control over her limb," said Dr. Hochberg. "I'm thrille
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Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

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