Navigation Links
Case Western Reserve University grants Thermalin Diabetes exclusive license
Date:11/29/2010

CLEVELAND Case Western Reserve University has granted an exclusive license on a portfolio of insulin analogs to Thermalin Diabetes, LLC, which has assembled more than $3 million to support the development of these important new drugs.

Cleveland-based Thermalin Diabetes is developing treatments that are expected to become an important part of the $12 billion, rapidly growing insulin market. Insulin is a therapeutic protein used to manage blood glucose (sugar) levels. Innovations in the 1990s led to the introduction of insulin analogs with superior therapeutic performance.

Thermalin Diabetes, which previously held an option on the insulin analogs, has now closed more than $2.2 million from private venture capital financing and individual angel investors, including $250,000 from Cleveland-based JumpStart Ventures. In addition, Thermalin has been awarded more than $1.1 million in Phase I SBIR/STTR grants by the National Institutes of Health (NIH). All of these funds are being used to help move innovative new insulin treatments toward the clinic.

Potential for improved treatment of Type 1 and Type 2 diabetes mellitus results from the work of Dr. Michael Weiss, chairman of the Biochemistry Department at Case Western Reserve University's School of Medicine. His approximately 20 years of research into the structure and function of biological molecules has focused on insulin, insulin analogs and insulin receptors.

New and improved insulin analogs will offer attractive alternatives for patients and may also revolutionize the use of insulin pumps. Insulin analogs are faster acting with fewer side effects, have stability without refrigeration, or are long acting with lower potential risk of cancer.

Weiss's scientific work with insulin has been aided students and fellows. Colleagues are Qing-xin Hua, Zhu-li Wan, Nelson Phillips, and Jonathan Whitaker, and long-term collaborators are Panno Katsoyannis, Bruce Frank, Steve Kent and Don Steinner.

The development of this technology was funded in part by the Wallace H. Coulter-Case Western Reserve University Translational Research Partnership.


'/>"/>

Contact: Marv Kropko
mrk107@case.edu
216-368-6890
Case Western Reserve University
Source:Eurekalert

Related medicine news :

1. Lung cancer patients are the centerpiece for Northwestern medicine quality of care study
2. Toronto Western Hospital study demonstrates improved wait times for patients suffering back pain
3. Circuit regulating anti-diabetic actions of serotonin uncovered by UT Southwestern researchers
4. Temperature rhythms keep body clocks in sync, UT Southwestern researchers find
5. UT Southwestern study to determine whether leptin helps type 1 diabetes patients
6. UT Southwestern researchers create experimental vaccine against Alzheimers
7. Blood test could diagnose Alzheimers disease, UT Southwestern researchers find
8. NIH awards $8 million to UT Southwestern to study metabolism, obesity-related inflammation
9. Lung cancer culprit could offer target for therapy, UT Southwestern researchers report
10. UT Southwestern University Hospital -- St. Paul recognized as Primary Stroke Center
11. Amphetamine use increases risk of aortic tears in young adults, UT Southwestern researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... 23, 2017 , ... ChenMed, a privately owned medical, management ... strategic executive team expansion needed to further optimize growth and performance. , “We ... Christopher Chen, MD, ChenMed Chief Executive Officer. “George Wheeler and Donald Trexler ...
(Date:3/23/2017)... ... 2017 , ... Sharon Kleyne, host of the nationally syndicated radio program, The ... recently talked on her program about how she is looking forward to World Water ... an important distinction. World Water Day, Kleyne pointed out, is an occasion for looking ...
(Date:3/23/2017)... Los Angeles, CA (PRWEB) , ... March 23, 2017 , ... ... half of all Americans, yet poor sleep is likely not the only cause of ... these undesirable characteristics that make you look older or in poor health are likely ...
(Date:3/23/2017)... ... March 23, 2017 , ... Natural Subsistence, a ... of people’s health and nutrition, announced its product Leyzene is now available for ... develops nutritional supplements that help people improve all aspects of their health so ...
(Date:3/23/2017)... Square, PA (PRWEB) , ... March 23, 2017 , ... ... days. That means many students are thinking about summer internships , which can ... lack thereof). , The pros at Garden Media Group, a boutique public relations firm ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 23, 2017 Global Colposcope Market by Manufacturers, ... Colposcope in Global market, especially in North America ... , South America , Middle East ... the market based on manufacturers, regions, type and application. ... Browse 190 Tables and Figures, ...
(Date:3/23/2017)... March 23, 2017   Casetabs , the pioneer ... mobile app for the iPhone. With this new release, ... and communication for physician offices, ambulatory surgery centers (ASCs) ... offers iPhone users even faster, more reliable access to ... even easier to connect care teams so that surgeries ...
(Date:3/23/2017)... , March 23, 2017 ReNeuron ... its CTX cells in chronic stroke patients, despite not meeting ... primary outcome measure, the Action Research Arm Test (ARAT). As ... to a pivotal controlled clinical study in 2017. Beyond CTX, ... (RP) trial in 2017 and Phase I data from its ...
Breaking Medicine Technology: