Navigation Links
Case Western Reserve University grants Thermalin Diabetes exclusive license
Date:11/29/2010

CLEVELAND Case Western Reserve University has granted an exclusive license on a portfolio of insulin analogs to Thermalin Diabetes, LLC, which has assembled more than $3 million to support the development of these important new drugs.

Cleveland-based Thermalin Diabetes is developing treatments that are expected to become an important part of the $12 billion, rapidly growing insulin market. Insulin is a therapeutic protein used to manage blood glucose (sugar) levels. Innovations in the 1990s led to the introduction of insulin analogs with superior therapeutic performance.

Thermalin Diabetes, which previously held an option on the insulin analogs, has now closed more than $2.2 million from private venture capital financing and individual angel investors, including $250,000 from Cleveland-based JumpStart Ventures. In addition, Thermalin has been awarded more than $1.1 million in Phase I SBIR/STTR grants by the National Institutes of Health (NIH). All of these funds are being used to help move innovative new insulin treatments toward the clinic.

Potential for improved treatment of Type 1 and Type 2 diabetes mellitus results from the work of Dr. Michael Weiss, chairman of the Biochemistry Department at Case Western Reserve University's School of Medicine. His approximately 20 years of research into the structure and function of biological molecules has focused on insulin, insulin analogs and insulin receptors.

New and improved insulin analogs will offer attractive alternatives for patients and may also revolutionize the use of insulin pumps. Insulin analogs are faster acting with fewer side effects, have stability without refrigeration, or are long acting with lower potential risk of cancer.

Weiss's scientific work with insulin has been aided students and fellows. Colleagues are Qing-xin Hua, Zhu-li Wan, Nelson Phillips, and Jonathan Whitaker, and long-term collaborators are Panno Katsoyannis, Bruce Frank, Steve Kent and Don Steinner.

The development of this technology was funded in part by the Wallace H. Coulter-Case Western Reserve University Translational Research Partnership.


'/>"/>

Contact: Marv Kropko
mrk107@case.edu
216-368-6890
Case Western Reserve University
Source:Eurekalert

Related medicine news :

1. Lung cancer patients are the centerpiece for Northwestern medicine quality of care study
2. Toronto Western Hospital study demonstrates improved wait times for patients suffering back pain
3. Circuit regulating anti-diabetic actions of serotonin uncovered by UT Southwestern researchers
4. Temperature rhythms keep body clocks in sync, UT Southwestern researchers find
5. UT Southwestern study to determine whether leptin helps type 1 diabetes patients
6. UT Southwestern researchers create experimental vaccine against Alzheimers
7. Blood test could diagnose Alzheimers disease, UT Southwestern researchers find
8. NIH awards $8 million to UT Southwestern to study metabolism, obesity-related inflammation
9. Lung cancer culprit could offer target for therapy, UT Southwestern researchers report
10. UT Southwestern University Hospital -- St. Paul recognized as Primary Stroke Center
11. Amphetamine use increases risk of aortic tears in young adults, UT Southwestern researchers report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/19/2017)... ... 2017 , ... Orbita, Inc., a leading provider ... Healthwise ® at HIMSS 2017 to showcase a breakthrough in remote ... technology and services, will demonstrate a voice-powered knowedge assistant based on Orbita ...
(Date:2/18/2017)... PA (PRWEB) , ... February 17, 2017 , ... Butler ... about the Stannah Stairlift and other Butler products. Ken was impressed with the ... and agreed to endorse the product on his show. This endorsement by Ken ...
(Date:2/18/2017)... ... February 18, 2017 , ... ProParagraph Fashion ... Film Studios ’ ProParagraph Fashion Volume 2 for all multi-line FCPX project needs. ... Users can pick and choose from hand-crafted trend-setting designs with smooth animations that ...
(Date:2/17/2017)... ... February 17, 2017 , ... ... kept pace. Enovate Medical has introduced an innovative workstation designed to reduce nursing ... nurses, the Encore Mobile EHR Workstation offers a lightweight, highly mobile, multi-functional alternative ...
(Date:2/17/2017)... , ... February 17, 2017 , ... ... brings its educational assistance management solution to the exhibit floor for the ... Orlando, Fla. , From Feb. 19–23, 2017, more than 40,000 healthcare industry ...
Breaking Medicine News(10 mins):
(Date:2/19/2017)... SAN FRANCISCO and ORLANDO, Fla. ... (Nasdaq: NKTR ) today announced that positive ... NKTR-214, in patients with renal cell carcinoma (RCC) were ... immuno-stimulatory therapy designed to expand specific cancer-fighting T cells ... tumor micro-environment and increase expression of PD-1 on these ...
(Date:2/18/2017)... , Feb. 17, 2017 Research and Markets has ... report to their offering. ... The report provides separate comprehensive analytics for the US, ... , Asia-Pacific , Latin America , ... period 2015 through 2022. Also, a six-year historic analysis is provided for ...
(Date:2/17/2017)... Cryoablation, Electrical, Endometrial Hydrothermal, Laser/Light, Microwave, Radiofrequency, Ultrasound, Cardiovascular, Gynaecology, ... expected to grow at a CAGR of 9.4% from 2017-2022 and ... at a CAGR of 9.5% from 2017 to 2027. The market ... ... benefit you Read on to discover how you can exploit ...
Breaking Medicine Technology: