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Carrington's DelSite Drug Delivery Technology Granted Patent From Eurasian Patent Office
Date:2/11/2008

nology enables production of vaccines or therapeutics that are preservative-free, room-temperature-stable, needle-free, and patient-friendly. In most cases, the needle-less administration afforded by the technology requires no medical professional. The GelSite(R) polymer is naturally derived and produced under cGMP with high purity, and requires no organic solvent use for production of the finished product. Eurasian countries are fast-developing economies and are obvious choices for obtaining patent protection."

GelSite(R) polymer is a high-molecular-weight-anionic polysaccharide that exhibits distinct chemical and functional properties proprietary to the Company. GelSite(R) polymer is water-based and is capable of in-situ gelation, i.e., changing from a solid or liquid into a gel upon contact with body fluids, leading to sustained release of active biomolecules. GelSite(R) polymer has also demonstrated muco-adhesive properties, making it highly suitable for mucosal delivery.

About GelSite(R) and GelVac(TM)

GelSite(R) polymer is not an adjuvant and is a member of a family of plant polysaccharides classified by the FDA as Generally Regarded As Safe (GRAS). The polymer is currently manufactured to cGMP standards at Carrington's wholly-owned subsidiary, Sabila Industrial, SA.

The GelVac(TM) system is a nasal powder vaccine delivery platform based on GelSite(R) polymer. Dry powder formulations delivered nasally provide several potential advantages, including better stability, room temperature storage, no need for preservatives, no need for needles, and mucoadhesiveness. Nasal immunization induces both systemic and mucosal immune responses. The GelVac(TM) delivery system increases antigen nasal residence time providing for prolonged contact with the mucosal surface, which may improve immune response for many different classes of antigens.

About DelSite

Carrington's wholly-owned subsidiary DelSite Biotechnologies, Inc., is develop
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SOURCE Carrington Laboratories, Inc.
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